Necrotizing sialometaplasia (NS) is a rare, benign, self-limiting lesion, but it mimics carcinoma both clinically and histologically. Authors present a case of NS on the right posterior hard palate in a 16-year-old boy. This case showed underlying erosive bone change on CT images. We supposed this lesion resulted from the local anesthesia for dental treatment. Presented NS is the only one case from approximately 1, 500 oral and maxillofacial biopsies (0.07%) at Chonnam National University Hospital during the period from 1999 to 2004.
Adolescent ; Anesthesia, Local ; Biopsy ; Humans ; Incidence* ; Jeollanam-do ; Male ; Palate, Hard ; Sialometaplasia, Necrotizing

Necrotizing sialometaplasia is a rare, benign, variably ulcerated, self-limiting disease of minor salivary glands. It may be frequently confused both clinically and histologically with squamous cell carcinoma or a minor salivary gland neoplasm. We present a case of necrotizing sialometaplasia on the inner surface of the lower lip developed in a 16-year-old man. To our knowledge, this is the first case repoit of necrotizing sialometaplasia in the Korean literature.
Adolescent ; Carcinoma, Squamous Cell ; Humans ; Lip ; Salivary Glands, Minor ; Sialometaplasia, Necrotizing* ; Ulcer

Necrotizing Sialometaplasia (NS) is a benign, self-limiting inflammatory disease of the mucus-secreting glands, and this illness mainly involves the minor salivary glands. The significance of NS resides in its clinical and histopathological resemblance to malignancy. We present here a case of necrotizing sialometaplasia on the soft palate, and this was accompanied by adenoid cystic carcinoma. We report here on this case to draw attention to the difficulty for deciding the extent of resecting a malignancy, and especially when the malignancy is simultaneously accompanied by necrotizing sialometaplasia.
Adenoids ; Carcinoma, Adenoid Cystic ; Palate, Soft ; Salivary Glands, Minor ; Sialometaplasia, Necrotizing

Necrotizing sialometaplasia (NS) which mimics malignancy both clinically and histopathologically is an uncommon benign, self-limiting inflammatory disease of the mucus-secreting minor salivary glands. The lesion is believed to be the result of vascular ischemia that may be initiated by trauma. Till date, the diagnosis of NS remains a challenge. This report demonstrates a case of NS in a 73-year-old male patient who presented with an ulcerative lesion in his palate. He had a history of local trauma and was long-term user of salbutamol inhaler. An incisional biopsy was carried out and the diagnosis was established through history, clinical examination, histopathology using Hematoxylin and Eosin stain. The patient was given symptomatic treatment and the lesion healed in about 7 weeks.
Aged ; Albuterol ; Biopsy ; Eosine Yellowish-(YS) ; Hematoxylin ; Humans ; Ischemia ; Male ; Nebulizers and Vaporizers ; Palate ; Saliva ; Salivary Glands, Minor ; Sialometaplasia, Necrotizing ; Ulcer

Necrotizing sialometaplasia (NS) was defined by Abrams et al. in 1973 as a reactive necrotizing inflammatory process involving minor salivary glands of the hard palate. Before that recognition, many patients with this condition had been improperly treated because of its clinical and histologic resemblance to malignancy such as mucoepidermoid carcinoma and squamous cell carcinoma. We report two cases of necrotizing sialometaplasia. One case involved a 58-year-old male who had an ulcerative palatal lesion exposing underlying bone which has the typical features of the above mentioned condition. Another case involved a 59-year-old male who developed a necrotizing sialometaplasia in association with a dome-shaped palatal swelling which was proved as an adenoid cystic carcinoma after operation biopsy.
Biopsy ; Carcinoma, Adenoid Cystic ; Carcinoma, Mucoepidermoid ; Carcinoma, Squamous Cell ; Humans ; Male ; Middle Aged ; Palate ; Palate, Hard ; Salivary Gland Diseases ; Salivary Glands, Minor ; Sialometaplasia, Necrotizing* ; Ulcer

Necrotizing sialometaplasia usually heals within 4 to 10 weeks with conservative treatment, and rarely recurs. When necrotizing sialometaplasia is present on the hard palate it may occur unilaterally or bilaterally. In this case, necrotizing ulceration occurred on the left hard palate of a 36-year-old woman after root canal treatment of the upper left first premolar under local anesthesia. After only saline irrigation the defect of the lesion completely healed and filled with soft tissue. After 5 months, however, a similar focal necrosis was found on the contralateral hard palate without any dental treatment having been performed on that side and progressed in similar fashion as the former lesion. We conducted an incisional biopsy and obtained a final pathological diagnosis for the palatal mass of necrotizing sialometaplasia. At the 3-year follow-up, the patient's oral mucosa of the hard palate was normal, without any signs and symptoms of the condition. We report a case of a second occurrence of necrotizing sialometaplasia on the contralateral side from the first, with a time lapse between the first and second occurrence.
Adult ; Anesthesia, Local ; Bicuspid ; Biopsy ; Dental Pulp Cavity ; Diagnosis ; Female ; Follow-Up Studies ; Humans ; Mouth Mucosa ; Necrosis ; Palate ; Palate, Hard* ; Recurrence* ; Sialometaplasia, Necrotizing* ; Ulcer