No abstract available.
Cheilitis ; Lip ; Sialadenitis

Humans ; Immunoglobulin G ; Sialadenitis

Isolated submandibular suppurative sialadenitis occurring in the neonatal period is extremely rare. At present, only 15 cases of isolated submandibular sialadenitis in the neonatal period have been reported in the literature. We report a rare case of multiple deep neck abscess in association with both submandibular suppurative sialadenitis in a term neonate.
Abscess* ; Humans ; Infant, Newborn ; Neck* ; Sialadenitis*

PURPOSE: Obstructive and inflammatory disease often occurs in the major salivary glands, and no predictive treatment has yet been developed for this condition. The aim of this report was to introduce an intraductal irrigation procedure and to illustrate its application to practical patient cases. MATERIALS AND METHODS: Two patients complaining of pain and swelling in the parotid gland during meals who underwent sialography were diagnosed as having sialodochitis with sialadenitis. Intraductal irrigation was then performed on the parotid gland on the side of the complaint. The irrigation procedure was conducted in the same manner as the sialography procedure, except that saline was used as the filling solution. Symptom severity was evaluated with a numerical rating scale (NRS) at the initial visit and a month after the irrigation. RESULTS: The initial NRS value of patient 1 was 10. The value decreased to 6 and then to 0 after 2 irrigation procedures. The NRS value of patient 2 regarding the symptoms involving the left parotid gland decreased from 4-5 to 1 after 4 irrigation procedures performed at 1-month intervals. CONCLUSION: Intraductal irrigation of the salivary gland may be a simple, safe, and effective treatment option for patients with obstructive and inflammatory disease of the salivary gland that is capable of resolving their symptoms.
Humans ; Meals ; Parotid Gland ; Salivary Glands* ; Sialadenitis ; Sialography ; Therapeutic Irrigation

A cavernous hemangioma of the submandibular gland is extremely rare. Cavernous hemangiomas often contain thrombi or phleboliths, which make it difficult for imaging to differentiate them from sialadenitis with calcification. We present two female patients, I and II, 41 and 16 years of age, respectively. They were referred for recurrent swelling in the submandibular area. A computed tomography scan demonstrated a cystic lesion with contrast enhancing vasculature and multiple nodular calcifications in the submandibular region. After surgical removal of the lesion, histopathological examination showed a cavernous hemangioma with phlebolith. The clinical feature of cavernous hemangioma of submandibular gland shows that repeated painful swelling is not related with eating. Histologically, phleboliths are calcified nodules that can be regarded as a pathognomic feature of a cavernous hemangioma.
Caves ; Eating ; Female ; Hemangioma, Cavernous ; Humans ; Sialadenitis ; Submandibular Gland

Chronic Disease ; Female ; Humans ; Middle Aged ; Sialadenitis ; Submandibular Gland Diseases

Salivary gland obstruction excluding neoplastic cause is the most common complaint affecting this organ, and it is usually due to sialadenitis, salivary stones, stenosis, inflammatory, or autoimmune etiology. Traditionally, when conservative management fails, surgical intervention was required afterward. The last 20 years have seen rapid development of minimally invasive sialendoscopy in diagnosing and treating salivary gland duct obstructions. Sialendoscopy is an excellent procedure that allows endoscopic visualization of the salivary ductal system, and it also provides an alternative in treatment choice before considering an open surgery which usually make surgeons to hesitate due to its invasiveness and its related complications. The goal of treatment now is to remain a physiologically intact gland, and at the same time to resolve the obstruction of the gland. In this article, the authors reviewed the current status of minimally invasive sialendoscopy.
Constriction, Pathologic ; Salivary Calculi ; Salivary Ducts ; Salivary Glands ; Sialadenitis

Immunoglobulin G4-related sialadenitis (IgG4-RS) is a newly recognized immune-mediated disease and one of immunoglobulin G4-related diseases (IgG4-RD). Our multidisciplinary research group investigated the clinicopathological characteristics and diagnosis of IgG4-RS during the past 10 years. Clinically, it showed multiple bilateral enlargement of major salivary glands (including sublingual and accessory parotid glands) and lacrimal glands. The comorbid diseases of head and neck region including rhinosinusitis, allergic rhinitis, and lymphadenopathy were commonly seen, which could occur more early than enlargement of major salivary glands. Internal organ involvements, such as autoimmune pancreatitis, sclerosing cholangitis, and interstitial pneumonia could also be seen. Thirty-five (38.5%) patients had the symptom of xerostomia. Saliva flow at rest was lower than normal. Secretory function was reduced more severely in the submandibular glands than in the parotid glands. Serum levels of IgG4 were elevated in almost all the cases and the majority of the patients had increased IgE levels. CT, ultrasonography, and sialography showed their imaging characteristics. Histologically it showed marked lymphoplasmacytic inflammation, large irregular lymphoid follicles with expanded germinal centers, prominent cellular interlobular fibrosis, eosinophil infiltration, and obliterative phlebitis. Their immunohistological examination showed marked IgG-positive and IgG4-positive plasma cell infiltration and high IgG4/IgG ratio. The disease could be divided into three stages according to severity of glandular fibrosis. The serum IgG4 level was higher and the saliva secretion lower as glandular fibrosis increased. IgG4-RS should be differentiated from other diseases with enlargement of major salivary gland and lacrimal gland, such as primary Sjögren syndrome, chronic obstructive submandibular sialadenitis, and eosinophilic hyperplastic lymphogranuloma.
Autoimmune Diseases ; Humans ; Immunoglobulin G ; Sialadenitis ; Sjogren's Syndrome ; Submandibular Gland

Salivary glands, major and minor, are susceptible to a wide variety of pathologic conditions. Excision of the submandibular gland is a surgical procedure often undertaken. The procedure is the treatment of choice for patients with neoplasm of the submandibular gland and those with non-neoplastic submandibular disorders which are not controlled with conservative medical measures. Extirpation of the submandibular gland may also be undertaken for diagnostic purposes. We evaluated 84 patients who had been admitted to the Dept. of oral and maxillofacial surgery of Pusan National University Hospital from January, 1989 to December, 2002 and had been performed submandibular gland excision. The results are as follows : 1. The patients undertaken the excision of the submandibular gland showed an age range of 16 to 71 years. The average was 49.1. 2. They consisted of 60 males(71.4%) and 24 females(28.6%), having 2.5 : 1 of genda ratio. 3. The most common symptom was swelling in 41 cases(48.8%), followed by the pain in 23 cases(27.4%). Other symptoms included mass, dysphagia, facial abnormaly and neck dyscinesia. 4. 42 cases(50.0%) showed sialadenitis and sialodochitis associated with salivary calculus. 5. According to the histopathologic study, all cases consisted of 17 neoplasmatic conditions(20.3%) and 67 non-neoplasmatic(79.7%). The neoplasmatic cases included 13 benign tumors and 4 primary malignant tumors. Sialadenitis and sialodochitis associated with or without salivary calculus were most marked, found in 50 cases(59.3%), in the non-neoplasmatic conditions. Pleoomorphic adenoma showed the highest frequency of the benign tumor.
Adenoma ; Busan ; Deglutition Disorders ; Humans ; Neck ; Salivary Calculi ; Salivary Glands ; Sialadenitis ; Submandibular Gland* ; Surgery, Oral

The purpose of this study was to established the characteristic radiographic features in salivary gland diseases by means of sialography and scintigraphy. Sialograms and scintigrams with diseases of salivary gland were examined. In this group were 5 salivary stones, 14 sialadenitis, 17 Sj gren's syndromes and 8 benign tumors. The obtained results were as follows; 1. In the configuration of the shape of main duct, those revealed that modified curvilinear and curvilinear types were predominant in Sj gren's syndromes but reverse sigmoid and angular types were in sialolithiasis and sialadenitis combined with sialodochitis. 2. In the configuration of the course of main duct, those revealed that smooth types were predominant in sialadenitis and irregular types were predominant in Sj gren's syndromes and benign tumors and irregular types were seen in all salivary stones and sialadenitis combined with sialodochitis, 3. In the type of intraglandular pattern, those revealed that destructive changes of salivary duct system and parenchyma were severe in sialadenitis and salivary stones and predominantly severe in Sj gren's syndromes. 4. The function of salivary gland was decreased severely in Sj gren's syndrome. and also decrease in salivary stone and sialadenitis. In benign tumor, the uptake of radioisotope was not seen in lesion and the function of salivary gland decreased in its remaining normal parenchyma.
Colon, Sigmoid ; Radionuclide Imaging ; Salivary Ducts ; Salivary Gland Calculi ; Salivary Gland Diseases ; Salivary Glands ; Sialadenitis ; Sialography*