Meta-Analysis as Topic

Humans ; Practice Guidelines as Topic ; Research Design

Due to the serious shortage of donor cornea materials and the donor limit, clinical popularization of penetrating keratoplasty is severely restricted. lt is a hot spot of current research that applying tissue engineering in vitro to culture corneal endothelial cells ( CEC ) with high density, regular hexagonal shape and healthy endothelial function. ln this article, we reviewed the latest progress in the study of source of CEC seeder cells, selection of cultivating carries, type of CEC transplantation and immune mechanism that summarized the current research problems and made a prospect to the future.

Animals ; Evidence-Based Medicine ; Health Knowledge, Attitudes, Practice ; Humans ; Infant ; Meta-Analysis as Topic ; Milk Hypersensitivity ; diagnosis ; prevention & control ; Milk Proteins ; adverse effects ; Practice Guidelines as Topic ; standards ; Professional Staff Committees ; organization & administration

Child ; Humans ; Incisor ; abnormalities ; Maxilla ; Occlusal Adjustment ; Orthodontic Extrusion ; Tooth Abnormalities ; diagnosis ; etiology ; therapy ; Tooth, Impacted ; diagnosis ; etiology ; therapy

Objective To investigate the diagnostic method and surgical therapeutic outcome of small peripheral pulmonary nodules (diameter ���2cm). Methods The data of 122 patients with small peripheral pulmonary nodules who were admitted from Jan. 2001 to Oct. 2010 and diagnosed by pathology postoperatively were retrospectively analyzed. The nodule diameter of nodules in 101 cases were 1-2 cm, and they were less than 1 cm in 21 cases. All the patients were examined by multislice spiral computed tomographic angiography (MSCTA), while 52 patients were examined by positron emission tomography/computed tomography (PET/CT), and 49 patients were subjected to CT-guided transthoracic needle biopsy (CTNB). The sensitivity, specificity and diagnostic accuracy were compared between the three methods for the diagnosis of lung cancer. Results Confirmed by postoperative pathological examination, 29 patients were suffering from benign lesions (23.8%), and 93 were with malignant lesions (76.2%). In the 85 patients with non-small cell lung cancer, only 56 (65.9%) were in early stage (Ia), and in 12(14.1%) hilar and mediastinal lymph node metastases were found. The sensitivity, specificity and diagnostic accuracy was 80.3%, 81.7% and 75.9% by MSCTA, 84.6%, 86.5% and 80.1% by PET/CT, and 91.8%, 88.6% and 100% by CTNB, respectively. The specificity of CTNB was better than that of MSCTA (P=0.045), and no significant difference was found in other indexes between MSCTA, PET/CT and CTNB (P>0.05). Conclusions MSCTA can serve as the first choice for the non-invasive diagnosis of small peripheral pulmonary nodules. Surgical operation is necessary for suspected malignant lesions, and CTNB can be selectively performed in patients who are considered to have benign lesions. In order to improve the speed and accuracy in locating the pulmonary nodules during the operation, the CT imaging should be carefully reviewed before operation in order to identify the location of the lesion, and CTguided transthoracic needle biopsy could be done when necessary.

Objective: To study the significance of DNA content in oral squamous cell carcinoma (SCC).Methods: DNA content and cell cycle of the cells in 18 cases of oral SCC were analized by image cytometry (ICM). Results: The DNA index (DI) and proliferation index (PI) were remarkably heigher in SCC than in normal epithelium ( P

Objective:To compare the characteristics of Dean's index(DI) and tooth surface index of fluorosis(TSIF). Methods:416 inhabitants of 12, 15 and 35~44 years old were sampled randomly to receive epidemiological survey assessed by DI in fluorosis endemic areas of Xingtai City, Hebei Province. Then TSIF was used to investigate the 178 samples selected randomly from the 416 subjects. Two examiners(S/C) were trained by an experienced specialist of epidemiology(W) before investigation. SPSS 10.0 software and Excel database were used to analyze the data.Results:Weighted Kappa of theoretic calibration of DI and TSIF was ranging from 0.86 to 0.96. The results of TSIF were lower than DI in clinical calibration test. With the increase of the number of tooth surfaces concerned, strength of agreement declined, ranging from “very good” to “moderate”. Prevalence of fluorosis according to DI was lower than that accoding to TSIF.In 35-44 years old people difference of fluorosis prevalence calculating between DI and TSIF was almost 40%. The most probably reason for this phenomenon was that a person with “questionable” fluorosis wouldn't be calculated as a fluorosis patient. The proportion of “questionable” in 35-44 age group was the highest (40.3%). Conclusion:DI is suitable for large-scale epidemiology survey, and should be combined with community fluorosis index (CFI), while TSIF is suitable for esthetic study, especially for severe fluorosis patients.

0.05). When comparing the pH value of xylitol gum with the pH value of 0.1 kg/L sucrose solution, and comparing that with the sucrose gum, significant difference could be found between the changes of pH values at different time points (P

[Abstract ] Objective Explore the clinical pathological characteristics and diagnostic methods on ent mucous epidermoid carcinoma.Methods Collection of 20 cases with ent mucous epidermoid carcinoma in our hospital,using immunohistochemical method to detect patients with CK and EMA,CEA and CK8 ex-pression.Results Twenty patients were men,of which the high differentiation of 17 cases,3 cases of poorly differentiated.CK ,EMA and CEA in patients with tumor tissue and CK8 were positive expression. Conclusions Ent mucous epidermoid carcinoma is a kind of relatively rare ent tumor,its clinical patholog-ical features and tumor tissue in CK and EMA,CEA and CK8 expressed help to identify and diagnosis.