1.Induction of TCSA Photocontact Hypersensitivity in Guinea Pigs.
Gwang Yoon CHO ; Si Yong KIM ; Won HOUH
Korean Journal of Dermatology 1985;23(2):199-203
S.I. of TCSA PCH (group B) and musk ambrette PCH (group D) were respectively g3 49% and 75.00 S.I. of group A and B, which were only challenged with TCSA and musk ambrette respectively without prior sensitization, were 33, 33% and 27. 78%. These data indicated the TCSA PCH (group B) was experimentally produced in guinea pigs when it compared to musk ambrette PCH (group D) and controls (group A and C) (Table 1). However, S.I. of TCSA PCH was somewhat lower than index of musk ambrette PCH.
Animals
;
Guinea Pigs*
;
Guinea*
;
Hypersensitivity*
2.Subperiostedal Ganglion of the Tibia: A Case Report
Won Kap LEE ; Hak Yoon OH ; Si Youl LEE
The Journal of the Korean Orthopaedic Association 1979;14(4):688-690
Subperiosteal Ganglion is a rare cystic lession, although ganglions are frequently found in close proximities to joints and tendon sheaths. It is characterized by a thin-walled cyst containing tenacious mucoid fluid and by the pedicle attached to periosteum. This report describes a middle-aged man with a subperiosteal ganglion which occured beneath the periosteam of the tibia. Presenting symptoms were pain and circumscribed swelling over the anteromedial aspect of the right proximal tibia.
Ganglion Cysts
;
Joints
;
Periosteum
;
Tendons
;
Tibia
3.Epidermolytic Hyperkeratosis Treated with Oral Vitamin A Palmitate.
Tae Yoon KIM ; Si Yong KIM ; Chung Won KIM ; Won HOUH
Korean Journal of Dermatology 1985;23(4):511-520
20-year-old patient presented with the episodes of generalized hyperkeratotic lesions with bullae since her early life, without family history. Histopathological examination by light and electron microscopes showed the characteristic features of epidermolytic hyperkeratosis. Primarily, she failed to respond to the treatment with propylene glycol. Vitamine A palmitate(A-Mulsin) per os appears to be a beneficial remedy for epidermolytic hyperkeratosis, although its availability is limited due to the side effects on a long term therapy. Repeated biopsies in the normal appearing lesions 2 months after treatment of vitarnin .A palmitate showed a substantial reduction of the horny layer on the light microscope and orderly arrangement of the tonofilaments, and properly formed keratohyaline granules on EM, but the underlying disorder of keratinization remained unchanged. Treattnent of 2 months with vitamin A was interrupted by side effects of nasal bleealing, chelitis and xerosis.
Biopsy
;
Humans
;
Hyperkeratosis, Epidermolytic*
;
Intermediate Filaments
;
Propylene Glycol
;
Vitamin A*
;
Vitamins*
;
Young Adult
4.A case of lichen aureus.
Sang Hyun CHO ; Tae Yoon KIM ; Si Yong KIM ; Baik Kee CHO ; Won HOUH
Korean Journal of Dermatology 1992;30(3):402-406
No abstract available.
Lichens*
5.Predictors of Left Atrial Thrombus in Mitral Stenosis A Transthoracic and Transesophageal Echocardiographic Study.
Han Soo KIM ; Namsik CHUNG ; Si Hoon PARK ; Junghan YOON ; Won Heum SHIM ; Seung Yun CHO ; Woong Ku LEE
Korean Circulation Journal 1992;22(5):791-797
BACKGROUND: Left atrial thrombus(LAT) has long been recognized as a complication of mitral stenosis(MS).The transesophageal echocardiographic approach readily visualize LAT. We evaluated the risk factors for left atrial thrombus in patients with MS using transthoracic(TTE) and transesophageal echocardiography(TEE). METHODS AND RESULTS: One hundred and forty-three(patients) who had moderate to severe MS were consecutively studied with TTE and TEE. They were 43 males(30%) and 100 females(70%).The mean age was 44+/-11 years(range 21-70). Twenty-five patients had at least one episode of embolic events. Ninety-six patients were in atrial fibrillation(AF). LAT was detected in 30 pts(21%) : 16 had thrombus confined to the LA appenge(LAA), 14 to true LA cavity and/or LAA. TTE variables were compared between LAT group and non-LAT group. Univariate predictors of LAT were mitral valve area(MVA)(0.78+/-0.22cm2 vs 1.05+/-0.32cm2, p=0.001), pressure half time(353+/-88ms vs 258+/-118ms, p=0.002). LV ejection fraction(EF)(55+/-11% vs 62+/-8%,p=0.008), LA size (58+/-11mm vs 52+/-7mm, p=0.033) and AF(p=0.001). Stepwise logistic regression analysis revealed significant independent predictors of LAT to be AF(p=0.02), MVA(p=0.02) and EF(p=0.03). CONCLUSION: Left atrial thrombus was not uncommon in patients with rheumatic mitral stenosis. Small mitral valve area and reduced ejection fraction of left ventricle appear to be significant predictors of LAT in mitral stenosis with atrial fibrillation.
Atrial Fibrillation
;
Echocardiography*
;
Heart Ventricles
;
Humans
;
Logistic Models
;
Mitral Valve
;
Mitral Valve Stenosis*
;
Risk Factors
;
Thrombosis*
6.A Case of Cutaneous Larva Migrans Improved by Oral Ivermectin
Hee Seong YOON ; Si Hyub LEE ; Seung Dohn YEOM ; Jeonghyun SHIN ; Gwang Seong CHOI ; Ji Won BYUN
Korean Journal of Dermatology 2018;56(1):70-72
No abstract available.
Ivermectin
;
Larva Migrans
7.Comparison of Hemostatic Effect of Endoscopic Injection with Fibrin Glue (FG) and Hypertonic Saline - epinephrine (HSE) for Peptic Ulcer Bleeding: A prospective randomized trial.
Young Myung MOON ; Jin Kyung KANG ; In Suh PARK ; Chae Yoon CHON ; Jae Bock CHUNG ; Kwang Hyub HAN ; Won Ho KIM ; Si Young SONG ; Wook Hee WON
Korean Journal of Gastrointestinal Endoscopy 1995;15(1):12-25
Endoscopic injection therapy using various different agents(ethanol, polidocanol, epinephrine with and without hypertonic saline, etc.) is considered as the least expensive and effective technique to obtain hemostasis in peptic ulcer bleeding, however most of these agents induce tissue necrosis or degeneration. Theoretically the injection of fibrin glue in peptic ulcer bleeding may be safer than that of other agents, however, to date, there have been no data from randomized clinical trials on the comparison of the efficacies between these agents. To compare the hemostatic efficacy between FG[Beriplast P, Behring, Germany] and HSE[3% saline and epinephrine(1: 10,000)], we conducted a prospective, randomized, clinical trial among one hundred twenty-seven patients with peptic ulcer bleeding from March, 1992 to December, 1993 and in whom a visible vessel or active bleeding was identified.
Epinephrine*
;
Fibrin Tissue Adhesive*
;
Fibrin*
;
Hemorrhage*
;
Hemostasis
;
Humans
;
Necrosis
;
Peptic Ulcer*
;
Prospective Studies*
8.Colon Cancer Secondary to Hematologic Disease.
Do Hyoung KIM ; Sung Bae JEE ; Youn SI ; Yoon Suk LEE ; Won Kyung KANG ; Seong Taek OH ; In Kyu LEE
Journal of the Korean Society of Coloproctology 2009;25(4):248-251
PURPOSE: The incidence of secondary malignancies in hematologic patients is known to be higher than it is in other patients. However, the characteristics of secondary malignancy and surveillance have not yet been established for colorectal cancer in leukemic patients. METHODS: From 1995 to 2007, 6,030 patients who were diagnosed with acute myeloid leukemia (AML), acute lymphoid leukemia (ALL), chronic myeloid leukemia (CML), chronic lymphoid leukemia (CLL), and multiple myeloma (MM) were enrolled in this study. Among them, 9 patients were diagnosed with colorectal cancer at St. Mary's Hospital and were analyzed retrospectively. RESULTS: Three of the 2,570 patients with AML, 1 of the 1,158 patients with CML, 2 of the 83 patients with CLL, 2 of the 422 patients with MM, and none of the 1,797 patients with ALL were found to have colorectal cancer. There were no operative mortalities, but 2 patients refused to have surgery. The ratio of observed to expected subsequent colorectal cancer in CLL was higher than it was in the other groups, indicating that the relative risk of colorectal cancer is higher in patients with CLL. CONCLUSION: Compared to the Surveillance, Epidemiology and End-Result (SEER) program at the National Cancer Institute (NCI) in the United State, we have the same high relatively risk in CLL patients. Careful attention should be paid to the possibility of colorectal cancer in CLL patients.
Colon
;
Colonic Neoplasms
;
Colorectal Neoplasms
;
Hematologic Diseases
;
Humans
;
Incidence
;
Leukemia
;
Leukemia, Lymphoid
;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
;
Leukemia, Myeloid, Acute
;
Multiple Myeloma
;
National Cancer Institute (U.S.)
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
Retrospective Studies
9.Efficacy of Transesophageal Echocardiography in Detecting Aortic Dissection.
Han Soo KIM ; Jung Han YOON ; Si Hoon PARK ; Byung Ok KIM ; Namsik CHUNG ; Won Heum SHIM ; Seung Yun CHO ; Sung Soon KIM ; Woong Ku LEE
Korean Circulation Journal 1992;22(1):105-112
Aortic dissection is a medical emergency requiring prompt diagnosis and maybe emergency surgery especially if the ascending aorta is involved. We have performed transesophageal echocardiography(TEE) in 22 consecutive patients with suspected aortic dissection. The diagnosis was subsequently proven in 14 patients(9 males, 2 females, mean age 51+/-11years) on the basis of TEE. The results and effectiveness were compared with computed tomography (CT) and aortography. Seven patients had type I aortic dissection, three had type II and four had type III. Twelve patients had hypertension. There was aortic regurgitation in five of seven patients with type I dissection and in all three patients with type II dissection. Type I dissection was found by TEE in seven patients who had intimal flap showing parallel movement to the aortic wall. CT was positive in only three of five of these patients. Type II dissection was seen in three patients by TEE. CT demonstrated dissection in one of three of these patients. In one patient the false lumen was filled with a thrombus, which was negative at angiography. Type III dissection was found by TEE in four patients. CT was positive in two of four patients. Aortography was performed and positive in one patient. The starting point of aortic dissection could be demonstrated in all four patients by TEE. TEE was well tolerated by patients with aortic dissection and associated with no major complications. In conclusion. TEE was very useful in detecting aortic dissection and in providing a dynamic information of the intimal flap and of the presence and extent of luminal thrombus with flow dynamics.
Angiography
;
Aorta
;
Aortic Valve Insufficiency
;
Aortography
;
Diagnosis
;
Echocardiography, Transesophageal*
;
Emergencies
;
Female
;
Humans
;
Hypertension
;
Male
;
Phenobarbital
;
Thrombosis
10.A case of pulmonary epithelioid hemangioendothelioma.
Sang Hoon KIM ; Dae Jung SHIM ; Won Tae SEO ; Si Young LIM ; Seung Sei LEE ; Shin Ho KOOK ; Joo Seob KEUM ; Tae Yoon OH ; Woon Ha CHANG
Korean Journal of Medicine 1999;57(1):108-113
Epithelioid hemangioendothelioma(EH) is a rare vascular tumor of low-grade malignancy. It was previously described as intravascular bronchioloalveolar tumor (IVBAT). But electron microscopic study and immunohistochemical staining results have proved endothelial origin. Patients are usually asymptomatic and the tumors are found incidentally on routine chest X-rays. Most patients show a slowly progressive clinical course, even though some patients occasionally die as results of respiratory failure or extrathoracic complications. Confirmative diagnosis is made through thoracoscopic or open-lung biopsy. There is still no effective therapeutic modality for pulmonary EH. We have experienced a 55-year-old woman whose simple chest x-ray film revealed bilateral multiple small nodules. The nodules were histopathologically and immunohistochemically diagnosed as primary epithelioid hemangioendothelioma of the lung. The possibility of metastatic disease was excluded thorough clinical, laboratory and radiological studies. Comparison of radiographic chest film taken 3 years ago showed no significant progression of the pulmonary nodular lesions. Conservative management was instituted and careful 4 months follow-up showed no significant changes.
Biopsy
;
Diagnosis
;
Female
;
Follow-Up Studies
;
Hemangioendothelioma, Epithelioid*
;
Humans
;
Lung
;
Middle Aged
;
Respiratory Insufficiency
;
Thorax
;
X-Ray Film