No abstract available.
Myasthenia Gravis* ; Thymectomy*

Palliative open nephrostomy was done on 50 cases with advanced pelvic malignancy and benign conditions in the Department of Urology, Seoul National University Hospital during the period of March, 1979 to July, 1982. The results were as follows: 1. 20.5% (9/44) of our patients died without being discharged from the hospital after nephrostomy. 2. In advanced pelvic malignancy, only 52.6% of patients alive at 3 months and only 26.3% alive 6 months. 3. In advanced pelvic malignancy, the post-nephrostomy complication was 46.7% and the most common complication was various urinary problems. 4. The cause of death was multifactorical and impossible to define precisely. The nephrostomy complications were at least in part contributory to the deaths. 5. The terminal malignancy patients who might not expected to live six months and to lead a useful, relatively comfortable life outside the hospital after treatment could not have benefited from nephrostomy. Unavoidable cases, we recommended percutaneous nephrostomy and passage of ureteral catheters instead of open nephrostomy.
Cause of Death ; Humans ; Nephrostomy, Percutaneous ; Seoul ; Urinary Catheters ; Urology

To investigate long term effects of CAPD on the left ventricular function in end-stage renal disease patients, M-mode echocardiographic studies and measurement o fsystolic time intervals were performed in 20 CAPD cases, 28 hemodialysis cases and 29 uremic controls. Compared to the uremic control grup, the patients on CAPD treatment revealed significant improvement of ventricular contractility and reduction of volume. On the other hand in hemodialysis group, even though there was improvement of ventricular contractility, volume control was not adequate. In the systolic time interval measurement, it is postulated that increase of PEP/LVET ratio in CAPD group probably results from reduction of volume(preload) rather than from deranged ventricular function.
Echocardiography ; Hand ; Humans ; Kidney Failure, Chronic* ; Peritoneal Dialysis, Continuous Ambulatory* ; Renal Dialysis* ; Systole ; Ventricular Function ; Ventricular Function, Left

Endoscopic injection therapy using various different agents(ethanol, polidocanol, epinephrine with and without hypertonic saline, etc.) is considered as the least expensive and effective technique to obtain hemostasis in peptic ulcer bleeding, however most of these agents induce tissue necrosis or degeneration. Theoretically the injection of fibrin glue in peptic ulcer bleeding may be safer than that of other agents, however, to date, there have been no data from randomized clinical trials on the comparison of the efficacies between these agents. To compare the hemostatic efficacy between FG[Beriplast P, Behring, Germany] and HSE[3% saline and epinephrine(1: 10,000)], we conducted a prospective, randomized, clinical trial among one hundred twenty-seven patients with peptic ulcer bleeding from March, 1992 to December, 1993 and in whom a visible vessel or active bleeding was identified.
Epinephrine* ; Fibrin Tissue Adhesive* ; Fibrin* ; Hemorrhage* ; Hemostasis ; Humans ; Necrosis ; Peptic Ulcer* ; Prospective Studies*

Recently, the capability cannulating the ampulla of Vater through the endoscope makes it possible introduce the recording ctheter deeply into the common bile and main pancreatic duct. Using these techniques, several authors have measured intraductal pressures in controls and in patients with various biliary and pancreatic diseases. Csendes et al. (continue...)
Ampulla of Vater ; Bile ; Endoscopes ; Humans ; Manometry* ; Pancreatic Diseases ; Pancreatic Ducts ; Sphincter of Oddi*

BACKGROUND: The apolipoprotein E (APOE) epsilon4 allele is over-represented in Alzheimer's disease, atherosclerosis, and ischemic heart disease. We investigated whether specific APOE polymorphism is a risk factor for ischemic cerebrovas-cular disease in the Korean population. METHODS: We compared 98 patients with ischemic cerebrovascular disease with 209 controls similar in age and dwelling areas. APOE genotypes were determined by restriction fragment-length poly-morphism analysis. The association of the APOE with: stroke subtypes, white matter hyperintensities, lipid profiles, and potential vascular risk factors, including: age, sex, hypertension, diabetes mellitus, lipid disorders, smoking habit, cardiac diseases, presence of past history and family history of ischemic cerebrovascular diseases, was examined. RESULTS: Overall, patients with ischemic cerebrovascular disease had no difference in APOE allele frequency with controls (p>0.05). Also, neither stroke subtypes nor white matter high signal intensities were associated with APOE polymorphism (p>0.05). APOE epsilon4 carriers exhibited more frequent personal stroke histories compared with non-epsilon4 subjects (p<0.01). CONCLUSIONS: Our data suggests that the APOE epsilon4 is not associated with ischemic cerebrovascular disease in the Korean population. However, an association between APOE epsilon4 and personal history supports the possibility that the APOE is a susceptibility locus for the risk of ischemic cerebrovascular diseases. (J Korean Neurol Assoc 19(1):19~23, 2001
Alleles ; Alzheimer Disease ; Apolipoprotein E4* ; Apolipoproteins E ; Apolipoproteins* ; Atherosclerosis ; Diabetes Mellitus ; Gene Frequency ; Genotype* ; Heart Diseases ; Humans ; Hypertension ; Korea* ; Myocardial Ischemia ; Risk Factors ; Smoke ; Smoking ; Stroke

BACKGROUND: Radiofrequency(RF) catheter ablation has been widely and successfully employed to cure young adult and old aged patients of a variety of arrhythmias. Only limited data exist which compare the results in two groups. The aim of this study was to compare the efficacy and safety of RF catheter ablation in old-aged patients(Group 1. older than 65 years old) versus young adult patients(Group 2. younger than 65 years old). METHOD: Clinical and electrophysiologic data were reviewd retrospectively in 385 patients who underwent radiofrequency catheter ablation from December. 1997 through May 2004. Procedure ralated results were used to compare 2 groups RESULTS: Mean age of each groups was 68.4+/-3.37 in group 1 versus 37.5+/-14.04 in group 2. There was no difference between two groups in gender, types of tachyarrhythmia, success rate, rate of complication and recurrence. No severe complications, such as death, vascular dissection, rupture, and major cerebrovascular accidents were present in either group. Procedure related variables, including fluroscopic time, were similar between 2 groups. CONCLUSION: RF catheter ablation is a safe and feasible primary treatment method for tachyarrhythmia in elderly patients, results similar to those achived with younger patients.
Aged* ; Arrhythmias, Cardiac ; Catheter Ablation* ; Electrophysiology ; Humans ; Recurrence ; Retrospective Studies ; Rupture ; Stroke ; Tachycardia* ; Young Adult

BACKGROUND: Radiofrequency(RF) catheter ablation has been widely and successfully employed to cure young adult and old aged patients of a variety of arrhythmias. Only limited data exist which compare the results in two groups. The aim of this study was to compare the efficacy and safety of RF catheter ablation in old-aged patients(Group 1. older than 65 years old) versus young adult patients(Group 2. younger than 65 years old). METHOD: Clinical and electrophysiologic data were reviewd retrospectively in 385 patients who underwent radiofrequency catheter ablation from December. 1997 through May 2004. Procedure ralated results were used to compare 2 groups RESULTS: Mean age of each groups was 68.4+/-3.37 in group 1 versus 37.5+/-14.04 in group 2. There was no difference between two groups in gender, types of tachyarrhythmia, success rate, rate of complication and recurrence. No severe complications, such as death, vascular dissection, rupture, and major cerebrovascular accidents were present in either group. Procedure related variables, including fluroscopic time, were similar between 2 groups. CONCLUSION: RF catheter ablation is a safe and feasible primary treatment method for tachyarrhythmia in elderly patients, results similar to those achived with younger patients.
Aged* ; Arrhythmias, Cardiac ; Catheter Ablation* ; Electrophysiology ; Humans ; Recurrence ; Retrospective Studies ; Rupture ; Stroke ; Tachycardia* ; Young Adult

The phenomenon of spontaneous regression, which is one of the characteristics of primary cutaneous CD 30 positive large cell lymphoma, has been observed in approximately one fourth of patients. However, complete regression is far less frequent than partial regression. We report a case of primary cutaneous CD 30 positive large cell lymphoma in a 53-year-old male patient who showed spontaneous complete regression without any treatment.
Humans ; Lymphoma* ; Male ; Middle Aged

Free muscle flap for the simultaneous coverage of two anatomically distant sites has previously entailed the harvest of tissue from separate donor areas, Although it may be possible to achieve this goal with a variety of available donor site, the transfer of a single donor muscle to two different sites has been considered. The gracilis muscle is commonly usef by reconstructive surgeon in a variety of application as pedicled muscle or musculocutaneous flap and as a free tissue transfer for soft tissue coverage or a functioning muscle transfer. The gracilis muscle is classified as having a type II blood supply that anatomy is reliable. The main arterial supply to the gracilis muscle is a branch of the profunda femoris, which enters the muscle 10+/-1cm from its attachment to the pubis on its deep(lateral) surface. The distal portion of muscle between the main arterial pedicle and musculotendinous junction is supplied by one to three small arterial branches of the superficial femoral artery. The first minor pedicle located approximately 20 cm from the pubis. In 1990 Tadeusz reported the successful treatment of patient with bilateral calcaneal fractures and posttraumatic osteomyelitis using a longitudinal single split free gracilis muscle transfer. In 2001 We performed a transversely dividing gracilis muscle free flap in the patient with two soft tissue defects and osteomyelitis in anterior tibial region and foot.
Femoral Artery ; Foot ; Free Tissue Flaps* ; Humans ; Myocutaneous Flap ; Osteomyelitis ; Tissue Donors