Lichen planus is a common, usually intensely pruritic papulosquamous dermatosis with unknown etiology, which may involve the skin, mucous membranes, hair follicles, and nails. Its lesions are usually a localized form but generalized ones are an unusual presentation of lichen planus. We report herein three cases of generalized lichen planus in one male and two female patients, which was diagnosed on clinical and histopathological examinations in all cases.
Female ; Hair Follicle ; Humans ; Lichen Planus* ; Lichens* ; Male ; Mucous Membrane ; Skin ; Skin Diseases

No abstract available.
Estradiol* ; Female ; Humans ; Plasma* ; Progesterone*

Endoscopic retrograde cholangiopancreatography (ERCP) is one of the most useful diagnostic tool in biliary and pancreatic disease. However, ERCP cannot be performed successfully in all patients. Cannulation failure is the most common cause of failure of ERCP. Mechanical pathologies, such as peri-Vater diverticulum, cancer of the papilla of Vater, and impacted stone were the common causes of cannulation failure. We experienced two cases of carcinoma of the papilla of Vater in whom cholangiography and insertion of the nasobiliary tube were performed througth an artificial choledoehoduodenal fistula made by a needle type diathermy knife, beacuse cannulation to the duct was failed due to the tumor.
Catheterization ; Cholangiography* ; Cholangiopancreatography, Endoscopic Retrograde ; Diathermy ; Diverticulum ; Fistula* ; Humans ; Needles ; Pancreatic Diseases ; Pathology

To date several agents have been used to achieve hemostasis in patients with bleeding peptic ulcers using endoscopic sclerotherapy techniques. In this study, the efficacy of endoscopic local injections of hypertonie saline-epinephrine(HS-E) solution, consisting of 9 volume of 3% sodium chloride and 1 volume of 1: 1000 epinephrine, on the base of the ulcer around bleeding vessel was assessed. During the period between April 1989 and July l992, 127 patients were admitted to the study. Ninety-six of these patients underwent endoscopic treatmeat(endoscopic treatment group), while the other 31 cases received conservative treatment only(conservative treatment group). (continue...)
Epinephrine* ; Hemorrhage* ; Hemostasis ; Humans ; Peptic Ulcer* ; Sclerotherapy ; Sodium Chloride ; Ulcer

PURPOSE: To compare the influences on the cornea between the WhiteStar mode and the continuous mode in the Sovereign(R) phacoemulsification unit after cataract surgery using temporal clear corneal incisions. METHODS: This study comprised 46 eyes of 23 patients who had cataracts in both eyes with similar grades of nucleosclerosis. The WhiteStar mode was used in one eye, and the continuous mode was used in the other eye. Pachymetry at the corneal center and 2 mm from the temporal limbus was performed. Topography and specular microscopy were performed, and surgically induced astigmatism was calculated using the Holladay-Cravy-Koch formula by simulated keratometric readings of Humphrey topography. Effective phaco time and average phaco power were recorded. RESULTS: Changes of corneal thickness at the center of the eye and at the incision site were significantly lower in the WhiteStar mode than in the continuous mode at 1 month postoperatively. However, there was no significant difference in corneal thickness at either site and in other parameters measured at 2 months postoperatively. The effective phaco time in the WhiteStar mode was significantly lower than in the continuous mode for cataracts with a high grade of nucleosclerosis. CONCLUSIONS: The early postoperative corneal edema in the WhiteStar mode was less than in the continuous mode. However, there was no remarkable difference in corneal endothelial damage. The effectiveness of phacoemulsification in the WhiteStar mode was superior to that in the continuous mode, especially for dense cataracts.
Astigmatism ; Cataract ; Cornea* ; Corneal Edema ; Endothelium, Corneal ; Humans ; Microscopy ; Phacoemulsification ; Reading

BACKGROUND AND OBJECTIVES: Platelets play an important role in the pathogenesis of acute coronary syndrome. Prostacyclin inhibits platelet aggregation, smooth muscle cell proliferation and vasoconstriction, and it counteracts thromboxane A2 activity. The purpose of this study is to evaluate the association between a single nucleotide polymorphism in the prostacyclin synthase gene and myocardial infarction in Koreans. SUBJECTS AND METHODS: We studied total 119 patients (M: F=72: 47, mean ages=57.9). We compared 60 acute coronary syndrome patients who underwent coronary angiography with the diagnosis of acute myocardial infarction (MI), with 59 normal control group patients who had normal coronary angiograms. With the use of polymerase chain reaction-restriction fragment length polymorphism analysis, we identified a single nucleotide polymorphism, C1117A, in exon 8. RESULTS: The genotype distribution and allele frequencies were significantly different between the control group and MI group. Frequency of the genotype C1117A was: AA: AC: CC=3.4%: 30.5%: 66.1% in control group, respectively, and AA: AC: CC=1.7%: 10.0%: 88.3% in MI group, respectively. Prostacyclin synthase polymorphism was observed in the MI group and the control group, but the frequency of the CC genotype was high in MI group (odds ratio, 3.88; 95% CI 1.49-10.88, p=0.003). Compared to control group, being male, having diabetes, hypertension or obesity, and the smoking rate were high in MI group. There were not significantly differences between genotypes for clinical characteristics. CONCLUSION: We conclude that the C1117A polymorphism in exon 8 of the prostacyclin synthase gene is associated with MI, and it may be a genetic marker of MI in Koreans.
Acute Coronary Syndrome* ; Coronary Angiography ; Diagnosis ; Epoprostenol* ; Exons ; Gene Frequency ; Genetic Markers ; Genotype ; Humans ; Hypertension ; Male ; Myocardial Infarction ; Myocytes, Smooth Muscle ; Obesity ; Platelet Aggregation ; Polymorphism, Single Nucleotide ; Smoke ; Smoking ; Thromboxane A2 ; Vasoconstriction

PURPOSE: To evaluate the efficacy of two excimer laser systems with eye-tracker in the term of decentration amount. METHODS: We performed LASIK with LaserScan LSX(TM) (group 1, 39 eyes) and Allegretto Wave(TM) (group 2, 94 eyes), both of which were equipped with eye-tracker. The amount of decentration was measured on a difference map that was obtained from preoperative and postoperative corneal topography, and was compared between the two groups. RESULTS: The amount of decentration was significantly higher in group 1 (0.39 +/- 0.22 mm) than in group 2 (0.29 +/- 0.18 mm) (p=0.018). When these groups were subdivided by preoperative spherical equivalent, in case of under -6.0 D, the amount of decentration between the two groups (0.31 +/- 0.16 mm in group 1, 0.28 +/- 0.15 mm in group 2, p=0.380), whereas in case of over -6.0 D, the amount of decentration was significantly higher in group 1 (0.48 +/- 0.26 mm) than in group 2 (0.30 +/- 0.21 mm) (p=0.020). CONCLUSIONS: Allegretto Wave(TM) showed better centration ability than LaserScan LSX(TM) and this superiority was more profound in highly myopic eyes.
Corneal Topography ; Keratomileusis, Laser In Situ* ; Lasers, Excimer

PURPOSE: To evaluate the cause of dark arcuate striae observed in infrared photographs in idiopathic epiretinal membrane (ERM) and macular hole patients after internal limiting membrane (ILM) peeling. METHODS: Forty patients (41 eyes) of idiopathic ERM and macular hole who underwent trans pars plana vitrectomy with ILM peeling and gas tamponade were included in the present study. The best corrected visual acuity (BCVA) was recorded at preoperative and postoperative 6 months. Infrared (IR) photography with spectral domain optical coherence tomography (SD-OCT) were obtained at preoperative and postoperative 1 week, 1 month, 3 months, and 6 months. When abnormal findings were visible on IR photographs, additional SD-OCT was performed at the corresponding sites. RESULTS: Of 40 patients, 4 patients demonstrated dark striae extending from the optic nerve to near macular area in IR photographs at 1 week postoperatively. SD-OCT images of the dark striae region revealed the swelling of retinal nerve fiber layer (RNFL). At postoperative 6 months, however, RNFL swelling previously observed subsided in all 4 cases, while temporal retinal thinning and dimples were observed in 3 cases. The preoperative and postoperative BCVA did not show any statistical difference between the patients with the RNFL swelling and the patients without the swelling. CONCLUSIONS: Swelling of RNFL may occur in idiopathic ERM and macular hole patients after pars plana vitrectomy and ILM peeling, which may present as dark striae in IR photographs.
Epiretinal Membrane ; Humans ; Membranes* ; Nerve Fibers* ; Optic Nerve ; Photography ; Retinal Perforations ; Retinaldehyde* ; Tomography, Optical Coherence ; Visual Acuity ; Vitrectomy

This paper is presented to report the results of urinary quantitative culture and drug sensitivity tests for isolated micro-organisms in this study. Studies were done on 172 cases from the department of Urology, Eul Ji General Hospital during the period from Jan. 1979 up to Dec. 1980. 1. Quantitative urine culture in 172 cases were performed and of these, 89 cases grew micro-organism wile the remaining 83 cases showed no growth. Among the 89 cases, 67 cases (75.2%) revealed significant bacteriuria with colony count over 10 5/ml in urine while 22 cases (24. 8%) were below 105/ml. Radio of Male: Female is 29: 38 2. 55 cases (82.1%) among the 67 cases with significant bacteriuria could the bacteria be identified on a smear and Gram stain. 54 cases (80.6%) of the 67 significant bacteriuria casts revealed pyuria of more than 5/HPF while 13 cases (19.4%) were below 5/HPF 3. 60 cases(89. 6%) of the 67 cases significant bacteriuria has Gram (-) bacilli while 7 cases(10.4 %) were Gram (+) cocci by direct smear. The frequency of isolated organism were as following E. coli 33 cases (49. 3%). Pseudomonas 11 cases(16.4%) Enterobactor 6 cases(9.0%) Proteus and stapbylo. Aureus 4 cases(5.8%) respectively. 4. On the whole, all isolated micro-organisms showed considerable susceptibility to panimycin (82. 7%) and then frequency of susceptible drug were and then the frequency of susceptible drug were Cefamezine, Kedacillin, Gentamicin.
Bacteria ; Bacteriuria ; Cefazolin ; Female ; Gentamicins ; Hospitals, General ; Humans ; Lymphography* ; Male ; Proteus ; Pseudomonas ; Pyuria ; Urology

PURPOSE: This study was aimed to evaluate the efficacy of an eye-tracking system, in terms of the amount of decentration. Comparison was made between two LASIK groups operated with and without the use of eye-tracking system. METHODS: An eye-tracking system was used in 41 eyes(Group 1) and patient fixation alone without an eye-tracking system in 41 eyes(Group 2). Corneal topography(Humphrey ATLAS(TM) Corneal Topography System; Zeiss Humphrey Systems, Dublin, California, U.S.A.) was performed before surgery and 3 months postoperatively. The amount of ablation decentration was measured on the difference map obtained from the axial map. RESULTS: The mean +/-SD of decentration was 0.38 +/-0.23 mm in group 1, and 0.49 +/-0.24 mm in group 2(p=0.047). The amount of decentration was graded as follows: grade I(<0.5 mm); Grade II(0.5~1.0 mm); Grade III(>1.0 mm). Grade I, there was a significantly less decentration in group 1(p=0.037). For grade II, however, there was no significant difference between the two groups(p=0.766). CONCLUSIONS: Using eye-tracking system alone may not be effective in decreasing moderate decentration. Good fixation of the patients seemed to be as effective as an eye tracking system in achieving good ablation centration.
California ; Corneal Topography ; Humans ; Keratomileusis, Laser In Situ*