1.Cardiological nuclear medicine
Journal of Medical Research 2005;37(4):83-87
Cardiological nuclear medicine was divided into two parts: diagnosis in vivo and diagnosis in vitro. Diagnosis in vivo need to put radioactive agents into patients, through dynamic and metabolic processes of radioactive agents and by using outside-body devices to gain parameters and images which reflect the physical and functional condition of heart, heart valves and blood supply of coronary arteries. Diagnosis in vitro does not put radioactive agents into patients. It used radioimmunoassays and immunoradiometricassays. Using patients’ blood samples, they quantify some agents with low concentration in blood. These are uninvasive tests with high accuracy that useful in diagnosis, treatment and prognosis of various diseases.
Heart Diseases, Nuclear Medicine
2.The situation of nuclear medicine in the region and strategy of development of Vietnam
Journal of Vietnamese Medicine 2001;263(9):1-6
According to the situation of the nuclear medicine in the region and world, and Vietnam, the strategy of development of Vietnam was introduced including the situation and task of the health sector, the features and difficulties of establishment and development of the country’s nuclear medicine as well as solution for strategy of the development of the nuclear medicine.
Nuclear Medicine
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Growth & development
3.Curcumin reduces A?generation of neurons by PPAR? activation and BACE1 inhibition
Journal of Chongqing Medical University 2007;0(10):-
Objective: To investigate the inhibitory effects of Curcumin on A? generation in vitro and explore its potential mechanisms involing BACE1 and PPAR?.Methods: Plasmids APPswe and BACE1-mychis were transiently co-transfected into SHSY5Y cells by LipofectaminTM2000,then treated with Curcumin at 0(control Group),1.25,5.0,20.0 ?mol/L for 24 hr,or with Curcumin at 5 ?mol/L for 0,12,24 and 48 hrs for the time course assay.RT-PCR was performed to measure the endogenous levels of BACE1 mRNA and PPAR?.Western blot were used to detect the protein expression of BACE1 and PPAR?.The major cleavage product——A?40 and A?42 was detected by ?-amyloid 1-40 or 42 Colorimetric ELISA assay.Results: The mRNA level and protein level of BACE1 were decreased obviously in a dose-and time-dependent manner after treated with Curcumin in the cell line(P
4.Review and prospect of tumor immunity research
Journal of Xi'an Jiaotong University(Medical Sciences) 1981;0(02):-
For over twenty years, the Insitute of Immunopathology of Xi'an Medical University, the antecedent Institute of Cancer Research, has long been engaged in the study on tumor immunity. Beginning with the exploration of the mechanisims for the activation of tumor-infiltrating lymphocytes(TIL) and tumor evasion till translating the relevant achievements into tumor immunotherapy and immunoprevention. From one facet, all the facts reflect the arduous course of the struggle of human beings for conquering cancer.
5.Inhibition of Yangyin Qingre Liqi Formula and Its Constituents on Tumor Growth of Esophageal Carcinoma Transplanted in Nude Mice
Journal of Traditional Chinese Medicine 1992;0(11):-
regulating qi group.The difference in tumor inhibitory rate of whole formula group and nourishing yin group was significant(P
6.ANALYSIS IN SITU ON ACTIVITY OF TUMORINFILTRATING LYMPHOCYTES IN HUMAN STOMACH AND COLON CANCER
Journal of Xi'an Jiaotong University(Medical Sciences) 1981;0(02):-
We have immunophenotyped the tumor-infiltrating mononuclear cells, especially the I_2 (HLA-DR) antigen and OKT_9 antigen expression on lymphocyte infiltrates to determine the activity of infiltrating T cells in 63 cases of advanced stomach and colon cancer. In addition, 18 specimens for biopsies from patients with chronic gastritis and colitis were used as controls. In most cancer specimens, the infiltrating T cells were defficient of I_2 antigen, only 10 out of 63 cases had about 10--30% I_2 positive infiltrating T cells, and nearly no OKT_9 positive infiltrating T lymphocytes. This finding is quite different from that in nomal mucosa and chronic inflammatory mucosa, with more I_2 positive lymphocytes in their infiltrates, indicating that the infiltrating T lymphocytes in tumor tissue inhibited by ome inhibitors present in their environment and contrabuting to the explanation why the tumor mmunity can not control the growth and spread of the tumor and lead to the elimination of the tumor.
7.Analysis and Clinical Intervention of Off-label Drug Use of Thymopentin in Our Hospital
China Pharmacy 2015;(32):4490-4492
OBJECTIVE:To provide reference for rational drug use in the clinic. METHODS:Medical records of 300 inpa-tients receiving thymopentin were randomly sampled from our hospital during Jul. 2013-Jun. 2014. The indication,solvent dilution, route of medication,dosage,medication course and contraindications were analyzed and evaluated. Comment result fed back and ef-fective clinical invention was done. RESULTS:There was a certain degree of off-label use of thymopentin,and the off-label drug use accounted for 38.33%. Through examination and clinical intervention on clinical rational drug use, remarkable results had been achieved. Thymopentin prescription sampling were analyzed statistically in the third quarter of 2014,and the off-label drug use rate dropped to 14%. CONCLUSIONS:We should strengthen prescription comments and feedback,effective clinical invention should be done,to promote rational use of thymopentin.
8.The States and Effect of Medical Moral Construction on Hospital Classified Administration
Chinese Medical Ethics 1995;0(03):-
The paper indicates the important status and effect of medical moral construction of medical classified administration from 3 aspects: 1) medical morals is the important content in hospital classified administration; 2) medical morals is its guarantee; 3) medical morals is the basis of consdiceting and developing achievements in classified administration.
9.Tissue-engineered tendon repairing tendon tissue defect induced by movement training: A correlated research of cell materials
Chinese Journal of Tissue Engineering Research 2010;14(16):2975-2978
BACKGROUND: Traditionally, tendon was repaired by autoallergic tendon transplantation and transfusion; however, both methods were limited by supply region and additional trauma, and the development was slowed down.OBJECTIVE: To summarize biomechanical characteristics of seed cells, stent, and bioreactor during repairing tendon tissue defect, and provide prevention and cure of tendon injury induced by training and competition.METHODS: A computer-based online search was conducted in VIP database with the keywords of "movement training, tendon tissue, repair" from January 2004 to October 2009.Articles which were related to tendon tissue injury induced by movement training were included, but articles related to duplicated research or Meta analysis were excluded.RESULTS AND CONCLUSION: Tissue-engineered tendon has achieved therapeutic effects to a certain degree; however, it is still not used for clinical application.Source of seed cells was restrict to autoallergic tendon cells; on the other hand, comparison between fibroblast and tendon cells, gene chip was used to modify gene in order to solve source of seed cells of tissue-engineered tendon.During regeneration of tendon, normal mechanical stimulation played an important role in moulding of newborn tendon.Because the stimulation might induce orientation arrangement of newborn collagen fiber, enhance mechanical strength of newborn tendon, make sure the functional training as eady as possibly, effectively reduce tendon adhesion, and provide an ideal stent for great circulation of tendon repairing.Scientific training is necessary for coaches and athletes to avoid from tendon tissue injury during movement training and competition.Although tendon tissue engineering has developed well, it still brings adverse effect on body and mind.
10.MRI manifestations of AIDS dementia complex
Journal of Practical Radiology 2017;33(9):1348-1351
Objective To analyse MRI findings of AIDS dementia complex to improve the understanding of this disease.Methods Clinical and MRI data of 35 cases of AIDS dementia complex were analyzed retrospectively.Results The total of brain tissue of 31 cases was reduced and cerebral cortex and basal ganglia showed diffuse atrophy;the sulci broadened and ventricle expanded.Lateral ventricle white matter of 25 cases showed signal abnormalities.3 cases of simple brain atrophy.Conclusion AIDS dementia complex has characteristic MRI findings,most patients had signs of brain atrophy,the sulci broadened and ventricle expanded;lateral ventricle white matter and centrum semiovale showed signal abnormalitiesCombined with the clinical history,MRI examination had important significance for the early diagnosis of this disease.