Objective To approach the treatment method to multiple trauma with fracture. Methods 232 cases with multiple trauma with fracture were treated in my hospital from 1994 to 2004. we did different and earlier treatment to different condition of injury. Results The 67 cases died among 4～48 hours after trauma. The 8 cases of the 162 cases hospitalized died. Conclusion Rescue with diagnosis, comprehensivly synthesize, analyze the patients condition and choose and decide the treatment scheme are primary measure to avoid complication, raise rescue survival rate and reduce deformity rate.

Antitussive Agents/*pharmacology ; Drug Evaluation, Preclinical/methods

Objective To explore the clinical efficacy of laparoscope in the treatment of nulliparous women with tremendous ovarian cysts .Methods 46 cases of nulliparous women were divided into the two groups according to the operation method .23 cases in the laparoscopic surgery group received laparoscopic pneumoperitoneum needle treatment.23 cases in the open group were given the traditional open surgery .Before operation,the umbilical region and vagina of these patients were cleaned ,and antibiotics was given to the two groups .The operative time,postopera-tive bleeding,exhaust time,hospitalization time,the number of cases of postoperative pain ,menstrual conditions and recovery time of daily living activities were compared .Results The operative time of the laparotomy group was (68.3 ±12.3)min,which was significantly longer than (59.6 ±11.5)min of the laparoscopic surgery (t=4.26,P<0.05).The number of pain after surgery in the laparoscopic surgery group and laparotomy group were 11 cases,21 cases. The incidence rate of postoperative pain in the laparoscopic surgery group was 47.8%,which was significantly lower than 91.3% in the laparotomy group (χ2 =10.3,P<0.05).Conclusion Laparoscopic treatment for nulliparous women with ovarian cysts showed shorter operative time ,less blood loss ,faster exhaust time ,shorter hospital stay ,less pain and faster recovery .This surgery scheme deserved to be introduced and further studied .

S_(3). The order of change range of the Q_(10) value of activity of dehydogenase is S_(1)

Pancreatic function diagnostant test (PFD) is performed with the oral administration of N-benzoyl-L-tryosyl-P-aminobenzoic acid (BT-PABA) .It is a specific test for the determination of the exocrine function of the pancreas. It can be more reliable if P-aminobenzoic acid absorbing test (PABA) is also performed to eliminate the intestinal, hepatic, and renal factors in PABA absorption and excretion.The authors used the combined method of PFD and PABA to study the pancreatic exicrine function in 32 cases of systemic lupus erythematosus (SLE) and 16 cases of dermatomyositis (DM) . It was found that lowed exocrine function of the pancreas occurred in 9.4% of SLE cases and in 18.8% of DM cases though no definite abdominal symptoms or signs could be observed in those cases. It is suggested that the combined PFD and PABA method be used in early SLE and DM cases to evaluate the pancreatic exocrine function.

Ways of effectively managing and using the scientific papers published by the personnel of an orga- nization so as to contribute to the enhancement of its scientific and technological strength and the level of its medical work are issues to be explored by file managing departments of scientific and medical institutions. On the one hand, the institutions should work out by administrative means various rules and regulations so as to standardize the filing of papers. On the other hand, the filing departments should enhance people's consciousness and initiative in placing their papers on file through excellent management and convenient service so as to bring the filing of scientific papers into a sound cycle. [

Objective To explore the techniques and clinical effects of surgical treatment for supratentorial hypertensive intracerebral hematoma (HICH) by modified minicraniotomy approach and bone fragment reduction.Methods The clinical data of 87 patients with supratentorial HICH in our department from April,2009 to April,2011 who received modified minicraniotomy approach and reduction of bone fragment were retrospectively reviewed.Results Of the 87 patients,three died,and the remaining 84 cases were followed up.According to the ADL( activities of daily living) scale,the patients were classified:Twenty-six cases in grade Ⅰ,28 in grade Ⅱ,22 in grade Ⅲ,6 in grade Ⅳ and 2 in grade Ⅴ.Conclusion The surgical procedure of modified minicraniotomy approach and reduction of bone fragment for treatment of supratentorial HICH has some advantages such as miniinvasion,good exposure,wide visual field,complete clearance of hematoma,integrated skull,and less complications.It is a perfect surgical procedure for supratentorial HICH.

Objective To study the effect of IFN-αcombined with ATRA in liver cancer therapy in perioperative phase of inter-vention .Methods An animal model of liver cancer CBRH7919 was established by implanting 28 Wistar rats with tumor tissue .The hepatic artery was tied off in one month after formation of tumor .All the rats were randomly divided into the experimental group (14 cases) and the control group(14 cases) .The control group accepted peritoneal injection with normal saline while the experimen-tal group accepted IFN-αcombined with ATRA .10 days later ,all the rats were sacrificed .And the level of expression of VEGF ,bF-GF ,mirovessel density ,and apoptotic index of tumor cells were measured .Results Serum VEGF level ,MVD and apoptotic index of tumor cells of the experimental group were statistically lower than that of the control group [(91 .8 ± 12 .7) pg/mL ,(115 .7 ± 11 .8)/HP ,(12 .29 ± 4 .53)% vs .(67 .4 ± 18 .3)pg/mL ,(65 .3 ± 7 .2)/HP ,(3 .81 ± 1 .52)% ,t=4 .099、13 .642、6 .640 ,P<0 .05)] , results of RT-PCR and immunohistochemistry detection both showed that the levels of expression of VEGF and bFGF of the exper-imental group was lower than that of the control group .Conclusion IFN-αcombined with ATRA in liver cancer therapy in periop-erative phase of intervention could suppress the generation of neoplastic vascular and improve the effect of the intervention .So it is worth promoting .

The effects of tetrandrine on serum TXB2, 6 - Keto - PGF1?, LPO and lipids in patients(n= 40)with essential hypertension has been studied. The results showed that: (1) The levels of serum 6 - Keto -PGF1?,apoA1 in EHT were lower and the level of serum TXB2,LPO and apoB100 were higher than those in control. (2)Patients with essential hypertension treated with tetrandrine (0.1 ~ 0. 2g,tid,po)for 3 mon revealed that thelevels of TXB2, LPO and apoB100 were decreased, and the levels of apoA1 and 6 - Keto - PGF1? were increased. In conslusion,tetrandrine stimulated the synthesis of PGI2 and inhibited the release of TXA2 and normalized the metabolism of lipids in patients with essential hypertension.

Hepatitis C virus (HCV) is a blood-borne virus transmitted through contact with blood and blood products,and it is a major cause of liver cirrhosis and hepatocellular carcinoma.Many epidemiological studies have confirmed the association between HCV infection and renal disease.Membranoproliferative glomerulonephritis associated with mixed cryoglobulinemia is the most common type of HCV-related renal disease manifesting as nephropathy or nephritic syndrome,proteinuria,hematuria,and reduced glomerular filtration rate.The treatment of HCV-related renal disease includes antiviral therapy,B cell clearance,and non-specific immunosuppressive therapy.At the same time,the launch of rnew antiviral drugs has brought hope to the patients who cannot tolerate conventional regimens.This article reviews the research advances in epidemiology,clinical manifestations,pathogenesis,and treatment of HCV-related renal injury.