1.Measurement of Levels of X-ray Radiation Emitted From Computer Video Display Terminals
Shuyu YUAN ; Fuyin SUN ;
Journal of Environment and Health 1992;0(05):-
To measure the levels of X ray radiation emitted from computer video display terminals Accumulative doses of X ray radiation emitted from the surface of terminal screen and radiation protcetive screen were measured by highly sensitive LiF(Mg,Cu,P) thermoluminescent dosimetry The average levels of X ray radiation emitted from the surface of terminal screen and radiation protective screen were 0 93 mR/d and 0 24 mR/d respectively [Conclusion]The low energy and low level X ray radiation emitted from the terminals didn′t exceed the related standards
2.Expression and clinical application of aromatasecy P450 and receptor of estrogen and progesterone in the tissue of endometrial cancinoma
Yan XING ; Shuyu WANG ; Lizhou SUN
Journal of Medical Postgraduates 2003;0(08):-
Objective:To study the expression of aromatasecy P450 and receptor of estrogen and progesterone in the tissue of endometrial hyperplasia and endometrial cancinoma,analysis the correlation of the endometrial carcinoma pathogenesis,clinical stage and cell differentiation.Methods:The immunohistochemiscal S-P method techniques were performed to study the expression of aromatasecy P450,estrogen receptor(ER) and progesterone receptor(PR) in the tissue of endometrium from 226 cases,including 42 cases of normal endometrium,52 cases of simple endometrial hyperplasia,38 cases of complex endometrial hyperplasia,36 cases of endometrial atypical hyperplasia and 58 cases of endometrial carcinoma.Results:There was no the positive expression in the normal endometrial tissues.But the positive expressions of aromatasecy P450 were found in the tissue of endometrial hyperplasia(simple endometrial hyperplasia,complex endometrial,atypical hyperplasia)and endometrial carcinoma.The rates of the positive expression were 40.4%,47.4%,69.4%,72.4% respectively.There were significant relationships among fifth groups(P
3.Progress in the studies on asterosaponins from starfish
Haifeng TANG ; Yanghua YI ; Shuyu ZHANG ; Peng SUN
Chinese Journal of Marine Drugs 2000;0(06):-
In this paper, a review and prospect to the progress in the studies on the chemical structures, pharmacological activities, methods of isolation and structural elucidation of as-terosaponins from starfish were reported.
4.Experimental measurements of dosimetric parameters of Ir-192 new source
Menglong ZHANG ; Yao SUN ; Liangan ZHANG ; Shuyu YUAN ; Guangfu DAI
Chinese Journal of Radiation Oncology 2010;19(5):468-470
Objective To perform thermoluminescent measurements of radial dose function and anisotropy function of a newly designed 192Ir microSelectron-HDR source, and establish evaluation methods for HDR dosimetry.Methods A polystyrene phantom with sylindrical holes in different measure positions was designed to accommodate thermo luminescent dosimeter (TLD) rods and radiation source.TLD rods with similar sensitivity were placed on a semicircle around the source center which had been precisely localized by either radiographic means or dose measurement.Dose-rates were measured at θ = 90° and r = 1-14 cm to calculate radial dose function (gL (r)), while measured along polar angles θ = 0° -165°(interval 15°) at radial distances r = 1 cm, 3 cm and 5 cm to calculate anisotropy function (F(r,θ)).All data were compared with those calculated by Monte Carlo (MC) method.The t-test was used for the statistics.Results The values of gL (r) were 1.007 -0.681 by calculation and 1.007 -0.598 by measurement with r = 1 - 14 cm(t = 0.00 - 2.89, all P > 0.05).The values of F (r,θ) were 0.631 - 1,0.660 - 1 and 0.696 - 1 by calculation, while 0.701 - 1, 0.668 - 1 and 0.629 - 1 by measurement at 1 cm, 3 cm and 5 cm with θ=0° -165°(t=0.40 -1.63, 0.02 -2.10, 0.08 -2.03, all P>0.05).Conclusions The results of radial dose function and anisotropy function measured by TLD measurement are in consistent with those calculated by MC calculations, which can be applied in treatment planning system as original input.
5.Expression and clinical significance of inhibitor of apoptosis protein XIAP in chiIdhood acute leukemia
Yanping ZHANG ; Taixin SHI ; Huiping ZHANG ; Shuyu LI ; Yanli SUN
Journal of Leukemia & Lymphoma 2008;17(6):445-447
Objective To investigate the expression and clinical significance of inhibitor of apoptosis protein XIAP in childhood acute leukemia(AL).Methotis The expression of XIAP protein was detected by immunohistochemical assay in 54 children with AL.including 26 newly diagnosed and untreated AL children.23 children in remission and 5 relapsed.The eontrol included 10 children with normal bone marrow.Results The level of XIAP proteins in the bone marrow of newly diagnosed AL children was higher than that in remission and normal controls(P<0.05),compared with that in relapsed children,with no statistical difference(P>0.05).The level of XIAP protein in remission was higher than that in normal controls(P<0.05).The level of XIAP protein in ALL and ANLL in newly diagnosed AL children was compared. with no statistical difference(P>0.05).Conclusion The higher expression of XIAP may contribute to the pathogenesis and the progress of the childhood AL.
6.Expression of epidermal growth factor receptor of cervical carcinoma and its correlation with prognosis
Linghong DENG ; Shuyu FENG ; Jiali KANG ; Yanna ZHANG ; Qiaoer LIN ; Miaoling NIE ; Haiyan CHENG ; Jinrui SUN
Clinical Medicine of China 2009;25(6):590-592
Objective To study the expression of epidermal growth factor receptor (EGFR) in cervical car-cinoma and cervical intraepithelial neoplasia(CIN),and to elucidate its relation with the genesis, infiltration, metas-tasis and prognosis of cervical carcinoma. Methods EGFR was determined by means of S-P immunohistochemistry in tissue of 100 cases of cervical carcinoma,60 cases of CIN and 40 cases of controls. Results The overexpression rates of EGFR were 0% (0/40), 51.67% (31/60),78.00% (78/100), respectively in normal cervical epithelium, CIN and cervical tumor tissues. The overexpression rate of EGFR was significantly higher in cervical tumor tissue than in control group(P<0.01). The overexpression of EGFR didn't demonstrate significant association with clinical staging, tumor size, pathological type, differentiation, cervical invasion depth, cervical canal invasion, lymphnode me-tastasis or the prognosis of cervical neoplasm (P>0.05). Conclusion Overexpression of EGFR is worsened with the severity of cervical lesion, suggesting that overexpression of EGFR is correlated with the genesis of cervical neo-plasms,which may be a valuable biological indicator of cervical carcinoma,but is not correlated with clinical patho-logical features and prognosis of cervical carcinoma.
7.Bacteria-blocking effect of surgical gowns with new material
Fei LU ; Tao LI ; Bin YANG ; Fei DONG ; Wei MENG ; Ziyao LI ; Wenkui SUN ; Shuyu CUI
Chinese Journal of Infection Control 2017;16(4):359-362
Objective To study bacteria-blocking effect of surgical gowns with new material.Methods Semi-quantitative and qualitative testing methods were used to detect bacteria-blocking rates of key sites of surgical gowns(chest and forearm), the detected samples included sample A (composite material, unused), sample B (composite material, after washing 100 times), and sample C (monolayer material, unused).Results In semi-quantitative testing,the average bacteria-blocking rates of three samples were 75.47%, 70.78%, and 73.73% respectively.In qualitative testing,three samples could effectively block the penetration of Staphylococcus aureus under wet condition and Bacillus subtilis var.niger spores under dry condition.Conclusion In semi-quantitative testing, all three kinds of samples had bacteria-blocking effect, and the average bacteria-blocking rate was> 70%;in qualitative testing, three samples all meet requirements of bacteria-blocking effect under wet and dry condition.
8.Risk factors of the prognosis of severe fever with thrombocytopenia syndrome infected by a novel bunyavirus: a retrospective analysis study
Shuyu JIANG ; Jingjun LV ; Jie WEI ; Shengnan SUN ; Rui WANG ; Weize YANG ; Dan TIAN
Chinese Journal of Emergency Medicine 2015;24(4):380-385
Objective To investigate risk factors of the prognosis of patients with severe fever with thrombocytopenia syndrome (SFTS).Methods From May 2012 to July 2014,17 cases of severe fever with thrombocytopenia syndrome in Renmin Hospital of Wuhan University were treated.Clinical data including history of epidemiology,clinical manifestations,complications,physical examination and laboratory test results on admission and the third day after admission were retrospectively analyzed and compared with the death group and recovery group by application of Spearman correlation analysis.Results Elderly male patients with neuropsychiatric symptoms,or abnormal liver function,or abnormal blood clotting function had higher risk of the poor prognosis.In SFTS patients,AST,ALT was significantly increased,AST 539 U/L (229.73,545.4) U/L (r =0.597,P =0.015) was a risk factor affecting prognosis.Elevated blood ammonia indicated serious liver dysfunction and neurological dysfunction which were manifested as irritability,delirium,and trembling limbs.In SFTS patients,platelets were significantly decreased accompanied with mouth ulcers / bleeding gums,gastrointestinal bleeding.PLT 24.88 × 10 9/L-1 (12.75,35.00) ×10 9/L-1 (r=0.557,P=0.005) or APTT 86.06 s (66.88,114.18) (r=0.798,P=0.001) or D-dimmer 9.79 mg / L (4.09,16.51) mg/L (r =0.597,P =0.015) are risk factors affecting poor prognosis.Conclusions On the third days after admission,AST,WBC,PLT,APTT,Ddimmer are risk factors for prognosis of patients with severe fever with thrombocytopenia syndrome infected by a novel bunyavirus.
9.Study on effects of paeonol in inhibiting growth of K_(562) and inducing its apoptosis
Guoping SUN ; Hua WANG ; Yuxian SHEN ; Zhimin ZHAI ; Wei WEI ; Shuyu XU
Chinese Pharmacological Bulletin 1986;0(05):-
AIM To investigate the effect of paeonol on proliferation and apoptosis of K 562. METHODS The inhibitory effect of paeonol on K 562 cells proliferation was assayed by MTT dye reduction. HE staining were used to observe the morphology of apoptotic cells, and Flow cytometric analysis were also used to analyze the K 562 apoptosis. RESULTS Pae at the concentration of 7.81~250 mg?L -1 significantly inhibited proliferation of K 562 cells in dose-dependent manner. Typical apoptotic changes were observed in K 562 cells under the light microscope. By FCM methods, the apoptotic rates of K 562 cells were increased from 10.01% to 34.16% after treatment of Pae at concentrations from 7.81 to 125 mg?L -1 for 24 h, which showed obvious concentration-effect relationship. The apoptotic rates of K 562 cells were also increased when Pae (6.25, 25 and 100 mg?L -1) was treated for 6, 12 and 24 h, which showed obvious time-effect relationship. CONCLUSION Paeonol may inhibit K 562 cell proliferation and induce its apoptosis.
10.EVALUATION ON DETECTION OF SHIGELLA CULTURES WITH THE DIAGNOSTIC TYPING PHAGE SET FOR ENTEROBACTERIACEAE
Jingxue LI ; Guoqing ZHOU ; Xianqin WEN ; Qinwen YU ; Qihua SUN ; Shuyu CUI ;
Microbiology 1992;0(06):-
In this paper , 2280 strains of suspicious Shigella c culture were detected by the diagnostic typing phage set for Enterobacteriaceae, the routine identification of them were carried oat at the same time . The results showed that 100% of shigella cultures were lysed with 10~3RTD and 99.9% lysed with 1RTD of phage Sh. 12.3% of 65 non-shigeUa cultures agglutinating with typing serum of shigeUa was lysed with 10~3RTD, 4.6% lysed with 1RTD of phage Sh. The determination of lytic-pattern of 2215 shigella culture indicated that only 3 strains of Boyd 5 of lytic-pattern 3 were not reported in literature, the rest strains were consistent to fomer studies. The nonshigella cultures lysed by Sh 10~3RTD could be excluded with 1RTD and its lytic-pattern. 20 strains of Enteroinvasive Escherichia coli possessing shigeUa-related antigens could be differentiated by Sh 10~3RTD. 1RTD and its lytic-pattern.