Three cases of intestinal T cell lymphoma(ITCL) were retrospectively reviewed in this study. Clinically, most patients with ITCL were middle aged males with abdominal pain, hematochezia,fever and weight loss. The outcome of treatment was worse with an extremely poor prognosis. The pathologic changes appeared to be the formation of intestianl ulcer manifested with multiplicity of shape,multifocal and unregularities. Tumor cells under microscopy were various obviously with diffused infiltration and medium to large cells were seen frequently. ITCL was often misdiagnosed because of clinical rarity and lack of characteristic manifestations, so physicians must pay more attention to the research of clinicopathological data,immunohistochemical features and gene type, so as to make early and correct diagnosis.

The prevalence of diabetes is reaching epidemic proportions worldwide.Elevated glucose levels and associated increases in blood pressure and dyslipidemia lead to long-term complications including cardiovascular disease,diabetic retinopathy,kidney disease,and nervous system damage.These complications are largely responsible for the great increase in morbidity and mortality seen in diabetes.Unfortunately,once established,diabetes is very diffi cult to treat,and it is currently exerting tremendous pressure on healthcare systems worldwide.For these reasons,diabetes prevention has become a key target for clinicians,patients and policymakers,and a number of potential strategies are under study.The purpose of this article is fi rst to discuss the defi ciency of current preventing strategies,and the potential role and the advantages of Traditional Chinese Medicine(TCM) to prevent diabetes.Following that,based on observational studies as well as on prospective trials,and with respect to the prevention and treatment of diabetes,the authors,therefore,suggest that the best way to approach prevention is through lifestyle modification guided by TCM theory.And those interventions should include not only herbs,but acupuncture,massage,food therapy and mind-body exercise,and they must examine cost-effectiveness as well.Future studies should also be designed with using such interventions and should be of suff icient duration to differentiate between genuine diabetes prevention as opposed to simple delay or masking of the disease.

Neural plasticity is one of the most important research area of developmental neurobiology. NMDA(N-Methyl-D-aspartate) receptor is one of the glutamate receptors in nervous system, which palys an important role in many biological and pathological changes, such as development of neural network, neural plasticity, learning and memory, degeneration of the neurons and so on. The studies on NMDA receptor with auditory plasticity and learning and memory were reviewed in order to make early intervention for hearing impaired children and provide a theoretical basis.
Auditory Perception ; Humans ; Learning ; Memory ; Nervous System ; Neuronal Plasticity ; Receptors, N-Methyl-D-Aspartate

Objective To investigate the clinical characteristics of Landau-Kleffner syndrome.Methods The clinical data of 3 patients with Landau-Kleffner syndrome was analyzed retrospectively.Results The clinical features of 3 cases presented acquired aphasia,epileptic attack and psychical behaviour abnormality.The EEG showed foci spike wave discharge,while the CT and MRI examination were normal.The epileptic attacks were controlled after treatment,but the recovery of aphasia and psychical behaviour abnormality was poor.Conclusions Acquired aphasia and epileptic attack are the clinical characteristics of Landau-Kleffner syndrome.The EEG shows spike wave dischargeis.Partial recovery can be obtained post-treatment.

Objective To investigate the clinical features of limbic epilepsies and limbic status epilepticus.Methods The clinical data of two patients with limbic epilepsies and one patient with limbic status epilepticus were analysed retrospectively.Results 2 patients with limbic epilepsia were all young-aged onset of the disease.They manifested bouts of unconsciousness,nervous and fear,various automatism and autonomic nerves symptom.EEG showed spike discharge in unilateral or bilateral temporal area.MRI showed left hippocampns sclerosis in one case.Another case presented calcification focus in right internal temporal.One patient with limbic status epilepticus was middle-aged male,he manifested repeatedly onset of unconscious insanity,behavior disorders and psychiatric symptoms.There was over 30 min for once onset.EEG showed ? wave or ? wave in bilateral frontal and temporal area.MRI showed arachnoid cyst in left temporal lobe anterior.Three cases were controlled by Carbamazepine or Oxcarbazepine.Conclusion The clinical feature of limbic epilepsies and limbic status epilepticus have bouts of automatism,automic nerve symptom and psychiatric symptom attact,which have relation to impairment of hippocampus and almond body in interal temporal.

0.05).Except that the wet weight of the epididymis in high-dose group of apigenin was significantly different compared with middle-dose group of apigenin(P 0.05).Cell cycle analysis showed that compared with the negative control group,the percent of diploid cells in low and high-dose group was decreased,the proportion of G0/G1 phase cells in low-dose group of apigenin was reduced(P

Objective To investigate the relationship between the mutagenicity of carbamazepine (CBZ) and folic acid (FA), and to explore the mechanism of CBZ teratogensis and the prevention effect of the folic acid. Methods Peripheral blood lymphocyte chromosome aberration rate (CAR), sister chromatid exchange (SCE)frequencies, and serum FA levels have been studied in 15 CBZ -treated epileptic patients, 15 CBZ plus FA-treated epileptic patients The untreated epileptic patients and the health subjects were served as controls Results CAR and SCE frequencies were significantly higher in CBZ group as compared with the CBZ plus FA group and the controls ( P

OBJECTIVE: To explore the efficacy and feasibility of compound glycyrrhizin in combination with anisodamine for the treatment of allergic purpura. METHODS: 60 patients with allergic purpura were randomly divided into treatment group and control group.The control group was given only the conventional therapy while the treatment group was treated with compound glycyrrhizin plus anisodamine in addition to the conventional therapy as stated in the control group. The course of treatment for both groups was 10 continuous days. RESULTS: The total effective rates for the treatment group and the control group were 90% and 60% (P

OBJECTIVE: To evaluate the efficacy of sublingual immunotherapy with dermatophagoides farina drops on children with allergic rhinitis. METHOD: This was retrospective study analyzing the efficacy of dermatophaguides farinae drops SLIT in 110 patients (aged 4-14 years old) with house dust mites induced allergic rhinitis (without asthma). All the patients were divided into the SLIT group (n = 60) and drug group (n = 50). Patients in SLIT group received sublingual immunotherapy combined with symptomatic medication, and patients in drug group only received symptomatic medication. We recorded and evaluated the total nasal symptom scores (TNSS), total medication scores (TMS) and visual analogue scale (VAS) of the 2 groups at three time points, before the treatment, and the treatment for 1-year and 2-year. RESULT: After 1-year and 2-year treatment, compared with drug group, TMS, TNSS and VAS in SLIT group decreased significantly (P < 0.01). When compared with baseline, we got the similar result as compared with drug group. Besides, the TMS of drug group increased significantly after treatment (P < 0.01). And no significant difference was observed in TNSS and VAS. In addition, there was significant difference in the Proportion of patients withdrawing symptomatic medication in SLIT group and drug group (68.33%,16.00%, respectively; P < 0.01). There were 4 local adverse reactions occurred during the treatment and no serious adverse events occurred. CONCLUSION Sublingual immunotherapy with Dermatophagoides farinae drops showed significant clinical efficacy in children with allergic rhinitis comparing with pharmacotherapy.
Administration, Sublingual ; Adolescent ; Animals ; Antigens, Dermatophagoides ; administration & dosage ; Asthma ; Child ; Child, Preschool ; Dermatophagoides farinae ; Humans ; Retrospective Studies ; Rhinitis, Allergic ; drug therapy ; Sublingual Immunotherapy ; Treatment Outcome

Knowledge-attitude-practice model is widely used in the self-management of type-2 diabetes.Through proper education,patients can gain diabetic knowledge as well as positive attitude on glucose control.By regulating diet,exercise,self glucose monitoring and medication compliance,diabetic patients are able to control blood glucose more effectively,and have less complications and higher quality of life.Researches on the application and effectiveness of various diabetic knowledge,attitude and self-management behavior scales are reviewed in this article.