Objective:In the medical cooperation, in order to realize the homogeneity of the medical, teaching, research, management, avoid to the waste of resources and the low benefit of patients with traditional cooperative mode. So combining the Internet and cloud computing technology to realize the reconstruction of the traditional mode of cooperation.Methods: Because of the need for equivalent cooperation, Beijing Friendship Hospital set up The Tiered Medical Work Platform Based on Medical image and Cloud Computing which between Beijing Friendship Hospital and Beijing Pinggu Hospital. The Work Platform was able to provides applications such as remote reading, remote diagnosis, remote consultation, remote difficult case discussion, remote teaching, training and so on.Results: The Work Platform solved the problem of wasting of human resource cost in our hospital, and improved the allocation of medical resources, improved the level of medical service of Beijing Pinggu Hospital, made people get benefits.Conclusion: Telemedicine technology can realize the reconstruction of traditional medical cooperation mode, establish standardized information sharing platform, increase the efficiency of medical resources allocation, improve the ability of primary diagnosis and treatment services, provide assist in forming the pattern of Tiered Medical.

Analyze the problems of medical insurance real-time settlement in outpatient department.Explore the situation of stringent management of health medical insurance agencies,accuracy of the information,significant increasing costs that medical insurance agencies refused to pay and severe environment to doctors.And management strategy such as regulating doctors' behavior strictly,upgrading hospital information systems,increasing hospital staff to excavate the hospital potential and publicizing the new policy of medical insurance comprehensively.

The hospital designed a new business process according to the business process reengineering theory and requirement of Diagnosis Related Groups-prospective payment.This new process has scored good outcomes following adjustment of department functions,staffing and equipment installation,as well as process optimization,and policy explanations.

Gonorrhea, caused by Neisseria gonorrhoeae, is one of the most frequently reported infectious diseases. With the increasing antibiotic resistance in Neisseria gonorrhoeae, gonorrhea has become a major public health problem worldwide, making it imperative to develop a safe and effective vaccine. Lipooligosaccharides (LOS), which exist on the outer surface of gram-negative bacteria, contain many important antigenic determinants. In recent years, a large number of studies have shown that LOS may become the most potential target of Neisseria gonorrhoeae vaccine and immunotherapy. This article reviewed the structure of LOS, its role in Neisseria gonorrhoeae infection, research progress in LOS vaccine and the challenges faced in vaccine development, aiming to provide reference for further study.