Objective To explore the clinical significance of minimally invasive plate osteosynthesis for old osteoporosis patients with intertrochanteric fractures.Methods 48 old osteoporosis patients with intertrochanteric fractures treated with minimally invasive plate osteosynthesis were seleited as experimental group;38 patients treated with conventional operation were selected as control group.Then we compared difference of two group on the treatment and complications.Results The rate of excellent or good for experimental group was 91.7％,and 84.2％ in control group.The difference was statistically significant( x2 =12.55,P ＜ 0.05 ) ;The complication rate was 0 in the experimental group,and 18.4％ in control group,which had statistically significant difference( x2 =15.23,P ＜ 0.05 ).Conclusion In the treatment of old osteoporosis patients with interurochanteric fractures,minimally invasive plate osteosynthesis is an ideal choice.With the correct rehabilitation exercise,appropriate surgical indications and right operation after the surgery could achieve the desired effect of surgery.

ObjectiveTo explore the effect of external fixation of damage control operation for treating severe multiple injury patients complicated with open tibia and fibula fractures.MethodsFiftyeight severe multiple injury patients complicated with open tibia and fibula fractures from June 2006 to February 2011 were reviewed.According to the control strategy for tibia and fibula fractures,all patients were divided into two groups:32 patients in observation group were treated with external fixation and 26 patients in control group were treated with calcaneal traction or gypsum external fixation.Wound healing time,fracture healing time,and the incidence rate of acute respiratory distress syndrome (ARDS) and multiorgan dysfunction syndrome (MODS),mortality and wound infection rate within 1 month between two groups were compared.ResultsIn observation group,incidence of ARDS and wound infection rate within 1 month,wound healing time was 6.25％(2/32),31.25％(10/32) and (21.47 ± 6.84) d,respectively,while 24.00％(6/25),64.00％ ( 16/25 ) and (30.26 ± 2.18 ) d in control group,respectively,there were significant differences between two groups(P ＜0.05).The differences of the incidence rate of MODS and mortality within 1 month,fracture healing time of observation group were not statistically significant compared with control group (P ＞ 0.05).ConclusionExternal fixation of damage control operation for treating severe multiple injury patients complicated with open tibia and fibula fractures has the advantages of reducing complication occurrence and improving success rate.

Objective To explore the gender heterogeneity of depression and thyroid hormone and homocysteine levels in infertile patients.Methods Totally 250 patients with infertility were selected in Tangshan Maternal and Child Health Care Hospital affiliated to North China University of Science and Technology from December 2015 to April 2017.The Self-Rating Depression Scale(SDS) was used to evaluated the patients's depression.The patients with infertility and depression were divided into infertility and depression group,and the patients with infertility but without depression were infertile and non-depressed group,patients with infertility and depression were divided into male infertility and depression group and female infertility group with depression,and the levels of thyroid hormone and homocysteine were measured respectively.Results ①The thyroid stimulating hormone and homocysteine levels in infertility patients with depression were significantly higher than those without depression ((2.045± 1.253) uIU/ml,(2.412± 1.236) uIU/ml,t=-2.287,P=0.023;(15.411 ±9.143) mmol/L,(19.129± 13.087) mmol/L,t=-2.467,P=0.014).②There was no statistically significant difference in the degree of depression between male and female infertility patients (x2=0.483,P=0.785).③ The levels of triodothyronine,thyroxine and homocysteine in male infertility patients with depression were significantly higher than those in female patients ((1.926±0.648)nmol/L,(1.712 ±0.416) nmol/L,t=2.457,P=0.015;(117.86± 19.311) nmol/L,(110.185± 18.999) nmol/L,t=2.434,P=0.016;(15.575±4.139) mmol/L,(12.277±3.921) mmol/L,t=4.982,P＜0.01),and the TSH was lower than that in the female group((2.496± 1.329) uIU/ml,(3.057± 1.583) uIU/ml,t=-2.303,P=0.023).④The TSH and Hcy levels of male and female infertility patients were significantly positively correlated with SDS indexes,and had a significant positive predictive power to SDS score.Conclusion The levels of thyroid hormone and homocysteine are different in gender in infertile patients with depression,and the thyroid hormone and homocysteine are related to the depression.so we should pay attention to the depression symptoms of infertility patients and the changes of their biological levels,especially the gender heterogeneity.