Neoadjuvant chemoradiotherapy followed by TME is a common treatment at present for locally advanced rectal cancer.Several studies abroad in recent years have shown that statins have a positive effect on cancer resistance.We discussed the mechanism and clinical application of statins in preoperative neoadjuvant chemoradiotherapy of locally advanced rectal cancer.

Influenza vaccination is considered the most effective measure to prevent the occurrence and pandemic of influenza.Beijing has implemented free influenza vaccination policy to the elderly above 60 years old and students in middle and primary schools since 2007.To provide a more effective intervention and let influenza vaccination achieve its role of immune protection among the population,the influenza vaccination rate and its influencing factors,barriers and driving factors of free influenza vaccination for recipients in Beijing have been studied successively.This article aims to summarize previous findings,review social factors influencing the vaccination and introduce the experience and lesson learnt from Beijing.