Objective To investigate the predisposing alleles of HLA-DR genes in pemphigus. Methods Polymerase chain reaction specific sequence primers (PCR-SSP) method was applied to type HLA-DR subregion in the patients with pemphigus vulgaris (PV), pemphigus erythematosus (PE) and matched control subjects of Han nationality from Jiangsu and Anhui provinces. Results The results demonstrated that DR4, DRB1*14 (*1401, *1404,*1405)gene frequencies were significantly higher in both PV(Pc

OBJECTIVE: To explore the diagnosis and treatment of the ectopic parathyroid gland in the pyriform sinus. METHOD: Retrospectively analysis of 1 case with ectopic parathyroid gland in the pyriform sinus and retrospectively review the past literatures. RESULT: The cases with the ectopic parathyroid gland in the pyriform sinus reported in the past literatures included: 2 with parathyroid gland tissues, 3 with hyperplasia, the other 1 with adenoma. The case reported by us was with adenoma. CONCLUSION The ectopic parathyroid gland hyperplasia in the pyriform sinus is rarely reported before and it usually causes misdiagnosis. Better knowledge of the different position of the ectopic parathyroid gland hyperplasia in the pyriform sinus will help diagnosing and treating it.
Choristoma ; diagnosis ; therapy ; Female ; Humans ; Hyperplasia ; therapy ; Middle Aged ; Parathyroid Diseases ; diagnosis ; therapy ; Parathyroid Glands ; pathology ; Pyriform Sinus ; pathology