Objective To observe and compare the blood lipid level in patients with colorectal polyps.Methods One hundred and twenty patients with colorectal polyps adminated in Shuangshan Hospital of Anshan from January 2011 to January 2014 were selected as observations and 120 healthy check-ups were selected as control group.The levels of serum total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol(LDL-C) of two groups were detected.Based on the pathological type and position of colorectal polyps and patients' gender, the blood lipid levels of sub-groups were compared.Results For observation group,there were single polyps in 81 cases ,multiple polyps in 39 cases and total colorectal polyps in 7 cases.There were 53 cases (44.17％) of hyperlipidemia (HLP).The levels of TC, TG and LDL-C of observation group were (5.26±0.97) mmol/L, (1.55±0.59) mmol/L, (2.88±0.67) mmol/L, significantly higher than those of control group ((4.51±1.02) mmol/L, (1.05±0.57) mmol/L, (2.43±0.39) mmol/L;t =4.08,4.27, 3.87, P＜0.05).the incidence of HLP based on the different pathological types were not significantly changed (P ＞ 0.05).The blood lipid levels based on the different pathological types were not significantly changed(P＞0.05).According to analysis results of adenomatous polyp, the incidence of tubular and villous adenoma HLP was significantly higher than that of tubular and villous adenoma(x2 =4.51, P＜0.05), while there was no significant difference in term of the blood lipid levels between the two groups(P＞0.05).The specific blood lipid levels were different (95％ CI 1.695-5.276, 1.823-3.517, 1.634-4.186;P ＜0.05).Conclusion TC and TG increase in patients with colorectal polyps.The clinical diagnosis and treatment shall focus on the detection of blood lipid levels.

It is the trend to integrate the curriculum contents and strengthen the ability training in reform of edu-cation model at present .After the abilities to develop and maintain medical informatics-related information sys-tems, to process medical information and to provide medical information service were analyzed, certain suggestions were put forward for the practical teaching reform of medical informatics according to the requirements of ability training and the characteristics of subject knowledge structure .

Dietary intake and biochemical parameters of zinc nutritional status in 270 pregnant women and 44 nonpregnant women have been studied and the results were as follows: 1.Dietary zinc intake was about 60% of RDA in both groups.2.The mean plasma Zn concentration declined progressively during gestation; the mean SOD activities and plasma Cu/Zn and alkaline phosphatase activities increased progressively.3.The zinc nutritional status of pregnant women in Beijing was poor. Using plasma Zn concentration less than 10.71 ?mol/l as a low limit, the incidence of zinc deficiency was 6.5%, 20.2% and 25.7% at each of three trimesters respectively.4.Plasma Zn concentration is more sensitive in evalution of nutritional status than hair Zn concentration. Plasma Cu/Zn could reflect zinc nutritional status. The mean SOD activities had similar trend with plasma Zn during pregnancy, and positive correlation with plasma Zn in second trimester (r= 0.2236,P

Objective To search for the CT and MRI morphological changes in the child patients with cerebral palsy. Method The CT scranning and MRI were carried out in 150 child patients with cerebral palsy, andthe results were analysed. Results In 150 cases, 97 cases (54.6 per cent) have abnormal findings of CT scranning. Diffuse ence-phalatrophy (42 cases), encephalomalacia focus (24 cases) porencephaly (9 cases), and localized ence-phalatrophy (7 cases) ect are the common CT morphological changes in the patients with cerebral palsy.In the 53 patients with normal findings of CT scranning, MRI was carried out for 30 cases and 25 cases(83.3 per cent) were abnormal. The delayed myelinogeny of white matter of brain is the main MRI mor-phalogical abnormality. Conclusion CT scranning and MRI have important value on the etiological diagnosis for child patientswith cerebral palsy. The combination of them can improve the diagnostic accordance rate.

Objective To explore the clinical effect of moist dressing combined with high energy narrow band phototherapy on chronic dermal ulcer.Methods Sixty cases with dermal chronic ulcer were randomly divided into two groups equally.The experimental group was treated by moist dressing combined with high energy narrow band phototherapy,while the control group was treated by moist dressing.The areas of wound surface were compared after treating for 14 and 21 days.Result Twenty-one days after treatment,the areas of wound surface were significantly reduced in the experimental group than that in the control group(P<0.05).Conclusion Moist dressing combined with high energy narrow band phototherapy can eradicate necrotic tissue,adjust micro-environment,and promote granulation and healing in chronic dermal ulcer.

Objective This study was designed to investigate the relationship between programmed cell death 5 (PDCD5) and endometrial carcinoma .Methods 60 tissue samples of endometrial carcinomas ,40 normal proliferative endometrium tissues and 28 endometrial atypical hyperplasia tissues were obtained from patients who underwent operation.The expression of PDCD5 was detected by Real-time PCR and immunohistochemical analysis . Results In normal proliferative endometrium , atypical hyperplasia tissues and endometrial carcinoma , the PDCD5 mRNA was gradually decreased[(1.21 ±0.16),(0.83 ±0.07),(0.42 ±0.02),F=5.637,P<0.05];The posi-tive rate of protein was gradually decreased (82.5%,64.3%,45.0%,χ2 =27.663,P<0.05);The expression of PDCD5 was correlated with TNM stage , histological grade , depth of myometrial invasion and lymphatic metastasis (χ2 =20.875,11.915,9.409,11.148,all P<0.05),but was not correlated with ages (χ2 =0.287,P>0.05). Conclusion PDCD5 might become a potential molecular marker of early diagnosis of endometrial carcinoma .

Objective Through this meta analysis of controlled clinical trials of the effect of aerobic exercise on the maximal oxygen uptake(VO_2max)in sedentary healthy adults,we attempt to provide evidence for exercise prescription.Methods MEDLINE search for controlled trials that involved in the effect of aerobic exercise on the VO_2max from 1976 to 2008 was conducted.The literatures were selected according to inclusion criteria and exclusion criteria.Review Manager 5.0 software provided a systematic evaluation for calculating VO_2 max Weighted Mean Difference with random effects model.Assessment of the sub-group of aerobic exercise intensity and literature publication bias were conducted.Results(1)Thirty five literatures were included in this review;involving 889 adults met the inclusion criteria.VO_2max Weighted Mean Difference is 3.61ml/kg/min,95%confidence interval 2.96～4.25ml/kg/min,with an increase of 13.2%,comparing with the average VO_2max values(27.26 ml/kg/min)before aerobic exercise.(2)The most effective exercise intensity was 70～80%VO_2max,71～80%HRmax and 61～70% HRR according to the sub.group of aerobic exercise intensity meta analysis.Conclusion VO_2max increased significantly due to participating in aerobic exercise in sedentary healthy adults.The results will provide a theoretical basis for me development of aerobic exercise prescription with appropriate intensity.

Objective:To analyze the impact of NBP on the expression of HSP 70 and TLR4 in the rat with ischemia-reperfusion.Methods:The 144 rats were divided into 3 groups,Sham group,IR group and NBP group.The 3 groups were divided into 4 groups again according to the time of reperfusion (6h,12h,24h and 48h).The intraluminal ischemia-reperfusion model was made by improved Longa.When the model was made successfully ,the rat in NBP group was gave oral NBP immediately while the IR and Sham group was gave oral NS.The neurological deficit scores , number of apoptotic cells , expression of HSP70 and TLR4 were compared during the 3 groups.Results:The neurological function ,apoptosis,the expression of HSP70 and TLR4 in NBP group at any reperfusion time were statistical lower than in IR group.In all the infusion periods,apoptotic cells in IR and NBP group were significantly higher than that in the Sham group.In all the infusion periods ,the positive cells in IR and NBP group were significantly lower than that in the Sham group.Conclusion:NBP can protect the function of neuron by improving the inhibition of HSP 70 and TLR4.

Objective Through this meta analysis of controlled clinical trials of the effect of aerobic exercise on the maximal oxygen uptake(VO2max) in sedentary healthy adults,we attempt to provide evidence for exercise prescription.Methods MEDLINE search for controlled trials that involved in the effect of aerobic exercise on the VO2max from 1976 to 2008 was conducted.The literatures were selected according to inclusion criteria and exclusion criteria.Review Manager 5.0 software provided a systematic evaluation for calculating VO2max Weighted Mean Difference with random effects model.Assessment of the sub-group of aerobic exercise intensity and literature publication bias were conducted.Results(1)Thirty five literatures were included in this review;involving 889 adults met the inclusion criteria.VO2max Weighted Mean Difference is 3.61ml/kg/min,95% confidence interval 2.96 ～ 4.25ml/kg/min,with an increase of 13.2%,comparing with the average VO2max values(27.26 ml/kg/min) before aerobic exercise.(2) The most effective exercise intensity was 70～80%VO2max,71～80% HRmax and 61～70% HRR according to the sub-group of aerobic exercise intensity meta analysis.Conclusion VO2max increased significantly due to participating in aerobic exercise in sedentary healthy adults.The results will provide a theoretical basis for the development of aerobic exercise prescription with appropriate intensity.

Objective To investigate the effect of optimized conditions on proliferation and differentiation of the neural stem cells(NSCs) from different age brain of rat in vitro. Methods The brain tissues from embryonic(E12～E15d),newborn(1～2?d) hippocampus and olfactory bulb from adult of rat were isolated.After proliferation in conditional culture medium including growth factor and induced differentiation,the cell type specific antibodies were used for the immune fluorescence staining to identify the cells. Results A lager scale NSCs were obtained from brain tissue and could proliferate in conditional culture in vitro. They could self renew and generate both nerve and glia.Conclusion\ The NSCs got from rat brain can be used for basic and clinical research.\;[