Objective To observe the clinical therapeutic effect of Wuzangshu Point Injection on Menses Mood Abnormity (MMA). Methods 60 cases were randomly recruited into a treatment group and a control group, with 30 cases in each. In the treatment group, Wuzangshu (a series points of Piyu, Shenyu, Xinyu, Ganyu, Neiguan) were point injected with Compound Chinese Angelica Injection; and the control group was treated only with taking Chinese patent medicine. The clinical effect was evaluated after 3 months' treatment. Results The total effective rate was 96.7% in the treatment group, which was significantly better than 73.0% in the control group (P<0.05) . Conclusion Point injection at Wuzangshu points is effective in treating MMA, and this method is worthy of spreading.

After a description of the concept of microvideo and studies on microvideo in domestic college and university libraries,microvideo in domestic college and university libraries was investigated and the production of microvideo was elaborated with Jining Medical College as an example.Strategies for the solution of problems in microvideo were put forward for its popularization.

Objective To evaluate the infection of high-risk human papillomavirus (HPV) and the expression of tumor metastasis suppressor protein KAI1 in cervical cancer.Methods The expression of KAH,HPV16/18E6 and HPV16E7 proteins were analyzed by immunohistochemistry SP assay in 117 cases of paraffin-embedded cervical tissue,including 20 normal cerival tissue as control,58 intraepithelial neoplasia (CIN) and 39 cervical cancer.Results In normal cervical tissue,CIN and cervical cancer,the positive rate of KAI1 protein were respectively 90.0 ％ (18/20),72.4 ％ (42/58),25.6 ％ (10/39).There was significant differience among three gruop (P ＜ 0.01).The positive rate of HPV16/18E6 and HPV16E7 proteins were respectively 0 (0/20),31.0 ％ (18/58),41.0 ％ (16/39); 0 (0/20),34.5 ％ (20/58),64.1％ (25/39).There were significant differience among three gruops (P ＜ 0.01).There was no correlation between the expression of KAI1 and the infection of HPV (P =0.429).Expression of KAI1 was correlated to grade of differentiation,clinical stage and lymph node metastasis (P ＜ 0.05),but was not correlated to age (P ＞ 0.05).HPV infection was not correlated to the age,clinical stage,cell differentiation and lymph node metastasis (P ＞ 0.05).Conclusion The expression of KAI1 protein is down-regulated in cervical cancer,which is not associated with the infection of HPV.

Objective To study the feasibility of using rough set and support vector machines to detect Parkinson disease. Methods The reduction algorithm based on the importance of the attributes in the rough set theory was used to reduce the common diagnosis features in the clinical practice. The support vector machines were applied for classification with the linear, polynomial and RBF kernel, and the Results were compare with that of BP neural network. Results The algorism combined attributes reduction and support vector machines appeared the highest accuracy of 92.71% in the classification, which seemed greater advantage in accuracy and stability than BP neural network. Conclusion Improving the accuracy of the classification as well as saving the resources, rough set and support vector machines are proved to be an effective method to assist the clinical diagnosis of Parkinson disease.

Objective To compare the distance of left ventricular along long axis measuring under real-time movement and Doppler tissue imaging.Methods Titanium nips were implanted into anterior wall and anterior septum of left ventricule of 7 open-chest canine models.Quantitative study was made on time velocity integral(TVI) of the implanted myocardium and left ventricular long axis in 7 canine models,and 7 patients with replaced metal mitral valve.Digital subtraction angiography was adopted to record the real-time movement of the titanium nips in 7 canine models and the metal valve in 7 patients.And comparison was made between the results.Results The maximum values of displacement measuring with TVI were close to the distance under real-time movement. Conclusions The displacement measuring with TVI can reflect the character of the myocardial displacement truly.

Objective To observe the inhibitory effect of xiaoaiping injection and octreotide on H22 tumor-bearing mice and find the best drug concentration,then to explore its mechanism.Methods Establish a mouse H22 subcutaneous tumor model.After tumor the experiment animals were divided into normal control group,model group,Xiaoaiping low,medium and high dose group,octreotide group,and the group of XAP low,medium and high dose groups were combined with OCT.Calculate the tumor's volume and draw the tumor growth curve.Intraperitoneal injection for 14 days,Inhibitory rate was calculated; To observe its pathological changes by light microscope; The ratio.of CD3 + NK1.1-T cells,CD3-NK1.1 + NKcells,CD3 + NK1.1 + NK-Tcells in peripheral blood were measured by flow cytometry.Results Compared with the control group,H22 liver cancer in different treatment group had a certain inhibition effect on growth,The inhibitory effect of the combination group was better than single-agent group,High-dose Xiaoaiping + octreotide was best,Tumor model group compared with normal control group,The ratio of T cells,NK cells and NKT cells was significantly lower(P ＜0.05) ; T cells,NK cells and NKT cells after treatment in each group had some enhancement,High-dose Xiaoaiping + octreotide was the most obvious,the ratio of T cells,NK cells and NKT cells of the combination group was significantly more than the single-drug group and the same concentration of octreotide monotherapy Xiaoaiping group(P ＜ 0.05).Conclusion High-dose Xiaoaiping + octreotide is the best drug for the inhibitory drug concentration.The inhibition of tumor growth may pass to improve the tumorbearing mice with immune status and enhance the body's anti-tumor capacity.

Objective: This item presents a feasible scheme of home monitoring device which is a low power and miniaturization equipment for human signal detection, based on single-chip technology. Methods: Taking MSP430F149 as core, the realized functions of system contain real time data acquisition, data processing, data storage, LCD and alarming, keyboard as well as com-munication, replay and reproeessing by host computer. Results: The physiological and biochemical parameters are acquired by system and transmitted to host computer. Conclusions: This design provides a platform for multi-parameters portable detection just as dynamic ecg, ambulatory blood pressure, and so on. It has a good future for application.

The left to right shunt rate(F)and the transverse seetional area of ductus arteriosus(A)were calculated by color Doppler flow convergence method in 20 patients with patent ductus arteriosus.The results indicated that the shunt rate(F)was correlated fairly with Qp-Qs,Qp/Qs(measured by pulsed wave Doppler),the pressure gradient(△P)and the diameter of left ventricle(DLV)(r=0.81,0.62,0.69 and 0.53;P＜0.001,0.005,0.001 and 0.01,respectively).The transverse sectional area of ductus arteriosus(A)was also correlated closely with the diameter of ductus arteriosus(Dd)measured directly in two-dimensional view(r=0.81,P＜0.001).The F value of group Qp/Qs≥2:1 was apparently higher than that of group Qp/Qs＜2:1(P＜0.005).The color Doppler flow convergence method can rapidly and exactly evaluate the left to right shunt severity of patent ductus arteriosus.

Objective To explore the indications and safety of video-assisted thoracoscopic lobectomy with small auxiliary incision for benign pulmonary diseases and non-small cell lung cancer.Methods Between May 1996 and April 2007,63 cases of lobectomy were performed by video-assisted thoracoscopy.Before the operation,18 of the patients were diagnosed with benign pulmonary diseases,and 45 had pulmonary mass or malignancies.Lobectomy of the right lung was carried out on 47 patients,including the right upper lobe resection in 12,the middle lobe in 8,and the lower in 27.The other 16 patients received resection of the left upper lobe(5)or left lower lobe(11).Results Thoracoscopic lobectomy was completed in all the 63 patients,in 6 of them the incision was lengthened during the operation.No perioperative death occurred.The chest tube was withdrawn 4 to 7 days(mean,4.5 days)after the operation.Postoperative pathological examination showed NSCLC in 37 patients(58.7%),metastatic lung cancer in 1(1.6%),carcinoid tumor in 1(1.6%),and benign conditions in 24(38.1%).Among the 37 patients with NSCLC,8 were at stage Ⅰa,13 at stage Ⅰb,14 at stage Ⅱa,3 at stage Ⅱb,6 at stage Ⅲa,1 at stage Ⅲb,and 2 at stage Ⅳ.Of the patients with malignancies,34 were followed up for 2 to 60 months(2 to 12 months in 7,13 to 24 months in 10,25 to 36 months in 6,37 to 48 months in 6,and 49 to 60 months in 3),2 of them survived 11 years,5 of the patients(14.7%)died of tumor recurrence or metastasis,1(2.9%)survived with tumor,and 28(82.4%)lived free of tumor.The 1-and 3-year survival rate of the patients with stage Ⅰ or Ⅱ cancer were 100%(19/19)and 90%(9/10)respectively.In the patients with stage Ⅲ cancer,5 received follow-up,3 of them died of recurrence of metastasis.In the 2 patients who had stage Ⅳ cancer,1 died of metastasis.Conclusion Video-assisted thoracoscopic lobectomy is a safe and effective procedure and can be a regular surgical treatment for benign pulmonary disease,and peripheral type non-small cell lung cancer at stage Ⅰ or Ⅱ.

Objective To report our experience on video-assisted thoracoscopic surgery(VAMT)for the treatment of benign esophageal neoplasm.Methods A total of 56 patients with benign esophageal neoplasm received VATS with or without auxiliary mini-thoracotomy in our hospital from March 1995 to January 2008.Under the assistance of a fiber gastroscope,through a 1.5-cm and two 2-cm incisions,the neoplasm was removed by using 3 trocars.In some cases,a 5-cm subaxillary incision was made.ResultsAmong the cases,the neoplasm was removed in 54 patients with VATS(with auxiliary mini-thoracotomy performed in 8),in which postoperative pathological examination showed esophageal leiomyoma in 47 and interstitialoma in 7.Two patients were converted to open surgery because of huge leiomyoma invading the muscular layer with an active growth,or low-malignant potential leiomyoma.Partial esophagectomy and end-to-end anastomosis were carried out in these two patients.No patient died intra-or peri-operation.No serious postoperative complication occurred in this series.A 2-to 128-month follow-up(mean,58.6 months)was achieved in 49 of the patients,none of them complained of dysphagia or developed recurrence during the period.Conclusions VATS(combined with mini-thoracotomy)is safe and effective for benign esophageal neoplasm.It can be the first choice for the treatment of the disease.