1.The Clinical Study on Dialectical Treatment of Acute Hemoptysis in Lung Cancer
International Journal of Traditional Chinese Medicine 2009;31(6):528-529
Objective To observe the clinical effects of dialectical treatment of acute hemoptysis in lung cancer. Methods A total of 289 patients with acute hemoptysis in lung cancer were randomly recruited into the two groups: a experimental group with 149 patients and a control group with 140 patients. The experimental group was treated on TCM syndrome differentiation, while the control group was treated with conventional western medicine. Results In the experimental group, the total effective rate was 91.3%. While in the control group, the total effective rate was 63.6% (χ~2= 32.13, P<0.01). There was significant difference between the two groups. Conclusion Dialectical treatment of acute hemoptysis in lung cancer is effective.
2.S95-100 field mobile medical system and its application
Shulin TAN ; Ruoxin LI ; Xinxi XU
Chinese Medical Equipment Journal 2003;0(S1):-
S95-100field mobile medical system is a field mobile hospital composed of such function cells as medical shelters,tents,special vehicles and transportable containers.Several logistic functions of the cells are introduced including patients checking and sorting,surgery,pre-operation preparation,emergency,clinical laboratory,medical supply,X-ray diagnosis,sterilization,medical command and communication,patient holding ward,logistic technical support and connection.The whole system assignments by different modules clipping and transformations,the application tests and widen tryouts in the army are alsopresented.
3.Development of NBC Filtration and Ventilation Unit
Yajun LIU ; Xinxi XU ; Shulin TAN
Chinese Medical Equipment Journal 1993;0(06):-
Objective To design and produce a kind of NBC filtration and ventilation unit with the function of filtering biological aerosols and chemical poisonous gas and so on in the air,providing new clean air for the medical shelter.Methods The filtration unit and ventilation unit were united in principle of manipulability and repairability by modularization method.Results Structural dimensions and vibrational noises of the unit were reduced,and manipulability and repairability were improved.Conclusion The unit can meet the demands of biological and chemical protection for the medical shelters,and the structural design of fast fitting and so on can meet the requirements of fast responses.
4.Research and key technology of info-visualization system of medical equipment
Jie NING ; Xinxi XU ; Shulin TAN
Chinese Medical Equipment Journal 2004;0(07):-
The technology of info-visualization is recommended.The main research of info-visualization system of medical equipment is proposed and the key technologies involved in that system are discussed.
5.CT appearance of thoracic lymphonodus in AIDS patients with immune reconstitution inflammatory syndrome
Shulin SONG ; Yibo LU ; Chunle QIN ; Chengzhi XU ; Zhili LI
Journal of Practical Radiology 2015;(10):1617-1619,1627
Objective To explore the CT appearance of thoracic lymphonodus in AIDS patients with immune reconstitution in-flammatory syndrome(IRIS)after highly active antiretroviral therapy (HAART).Methods The data of thoracic CT in 24 AIDS pa-tients after HAART with enlarged thoracic lymphonodus in IRIS were collected,and the chest CT appearance was analyzed.Results Of the 24 cases of AIDS patients with IRIS after HAART,1 9 cases were complicated with pulmonary tuberculosis,which includ-ed 5 cases with cervical tuberculous lymphadenitis,3 cases were co-infected with bacterium and fungi,1 case was infected by penicil-lium marneffei,1 case by pneumocystis carinii.The enlarged thoracic lymphonodus were primarily located in 4R region(20/24), secondly in 2R region(1 1/24)and 4L region(1 1/24),in which the density was uniform or non-uniform,edge clear or unclear,some parts of lymphonodus were fused together but not calcified.The minor axis of enlarged lymphonodus was 1 1.0-25.0 mm except X region,enhanced uniformly in 2 cases.Obstructive pneumonia and pulmonary consolidation were found in 2 cases with enlarged lym-phonodus,which were located in 10R region.Pleural effusion was found in 13 cases with greatest depth of about 22 mm,pericardial effusion was found in 5 cases with greatest depth of about 24 mm.Conclusion The enlarged thoracic lymphonodus in AIDS patients with IRIS affer HAART are mainly involved in the region of 4R,2R and 4L,with or without pleural effusion and pericardial effusion.
6.The prevalence and dynamics of human immunodeficiency virus-1 subtypes among men who have sex with men in Beijing
Wanhai WANG ; Liang MING ; Shulin JIANG ; Xiaoxi ZHANG ; Yiming SHAO ; Jianqing XU ; Quancheng KAN ; Xiaoyan ZHANG
Chinese Journal of Infectious Diseases 2012;(11):673-676
Objective To investigate the subtype distribution and changing trend of human immunodeficiency virus (HIV)-1 strains among men who have sex with men (MSM) during 2005-2011 in Beijing.Methods Five serial cross-sectional surveys of MSM were conducted in the year of 2005-2006,2007,2008,2009,and 2010-2011 in Chaoyang district of Beijing.Whole blood samples were collected and then RNA was extracted.HIV-1 gag gene was characterized by reverse transcriptase and nested polymerase chain reaction (RT-PCR) amplification,DNA sequencing,and phylogenetic analysis of viral sequences to determine the HIV-1 subtypes.Results Phylogenetic analysis of the sequences revealed that the predominant subtypes of HIV-1 gag gene included subtype B,CRF01_AE and CRF07_BC.And CRF15_01B was detected from the year of 2008.In addition,significant changes of the distributions of subtypes and CRFs occurred from 2005 to 2011 in HIV+ MSM.Subtype B showed a significant decreased trend,while the proportions of CRF01 _AE and CRF07_BC significantly increased in the 7-year period,particularly that of CRF01_AE.Conclusions The substantial changes are observed in the diversity of HIV-1 strains circulating among MSM in Beijing during a 7-year period.
7.Comparative analysis of the accuracy of visual qualitative assessment and semi-quantitative analysis in 18F-florbetaben β-amyloid imaging
Yan CHANG ; Hui YANG ; Shulin YAO ; Baixuan XU ; Ruimin WANG ; Jinming ZHANG
Chinese Journal of Nuclear Medicine and Molecular Imaging 2021;41(1):23-27
Objective:To compare the accuracy of visual qualitative assessment and semi-quantitative analysis for 18F-florbetaben ( 18F-FBB) β-amyloid (Aβ) imaging in the diagnosis of Alzheimer′s disease (AD) and to explore their clinical application value. Methods:From January 2019 to October 2019, 17 patients (8 males, 9 females, age (74.1±8.5) years) with mild/moderate-stage clinically probable AD and 17 cognitive normal control (NC; 9 males, 8 females, age (64.5±6.3) years) were prospectively enrolled in this study. All patients underwent dynamic 18F-FBB PET/CT brain imaging in the Chinese PLA General Hospital. Visual qualitative assessment and semi-quantitative analysis methods were used to analyze PET brain imaging results. The difference of standardized uptake value ratio (SUVR) between the two methods was analyzed by using independent sample t test. The consistency of the two methods and clinical results was analyzed by Kappa test. The cut-off value of SUVR for the diagnosis of AD was determined by receiver operating characteristic (ROC) curve. Results:The sensitivity, specificity and accuracy of visual qualitative assessment to diagnose AD were 14/17, 16/17 and 88.2% (30/34). The global SUVR of NC and AD group were 1.09±0.85 and 1.75±0.25 ( t=-10.263, P<0.001), and the composite SUVR were 1.16±0.57 and 1.89±0.15 ( t=-10.789, P<0.001), respectively. The cut-off value of SUVR for the diagnosis of AD was 1.47, with the sensitivity of 15/17, the specificity of 16/17 and the accuracy of 91.2%(31/34). The visual qualitative assessment and semi-quantitative analysis had good consistency with clinical diagnosis results with Kappa value of 0.765 and 0.824 respectively (both P<0.001). Conclusion:The visual qualitative assessment and semi-quantitative analysis methods used in 18F-FBB Aβ imaging to diagnose AD patients show high accuracy and can provide effective value for clinical diagnosis, but the visual qualitative assessment method is concise and easy to grasp, which is worth further promotion and use in clinical.
8.Detection of Genotypes of Plasmid-mediated AmpC ?-Lactamase and Analysis of Antimicrobial Resistance of Klebsiella pneumoniae in Harbin
Wenli ZHANG ; Fengmin ZHANG ; Yingmei FU ; Jianfeng XU ; Xiaobei CHEN ; Jiayu MA ; Shulin LIU
Chinese Journal of Nosocomiology 1994;0(04):-
OBJECTIVE To determine the drug resistance phenotype and genotype of plasmid-mediated AmpC ?-lactamase in Klebsiella pneumoniae isolated from Harbin.METHODS Isolates of K.pneumoniae with an inhibition ring to cefoxitin of ≤18 mm diameter were used.Antimicrobial susceptibilities were determined by disc diffusion method.AmpC genes were detected by PCR with six pairs of primers.RESULTS Sixty-three isolates had an inhibition ring to cefoxitin of ≤18 mm diameter and 26(11.3%)were detected to be AmpC-producing in a total of 231 clinical isolates of K.pneumoniae.Seventy-six percent,70.2%,53.8%,50.5%,57.7%,38.5% and 7.7% of AmpC-producers were resistant to cefoxitin,cefotaxime,ceftazidime,amoxicillin/clavulanic cid,ciprofloxacin,amikacin and imipenem,respectively.ACT,DHA and CIT types of AmpC beta-lactamase were detected in 13,8 and 5 isolates,respectively.No ACC,MOX and FOX were detected.CONCLUSIONS The AmpC ?-lactamase in Harbin is mainly in the types of ACT,DHA and CIT.AmpC-producing K.pneumoniae shows decreased susceptibilities to cefoxitin and third generation cephalosporins.
9.Research on Compartment Environmental Quality of Ambulance Against Biological Contamination
Xinxi XU ; Yajun LIU ; Xiangdong CUI ; Limei HAO ; Shulin TAN ; Meng WANG ; Xiuguo ZHAO
Chinese Medical Equipment Journal 2009;30(7):2-6,插页7-3,插页7-4
Obiective To study the compartment environmental quality of ambulance against biological contamination for safe and comfortable transportation and treatment of patients. Methods The experimental research and numerical simulation were carried to master the state of compartment environmental quality, Results Compartment environment indexes excel technology demands, such as overpressure/negative-pressure, temperature, biological contamination, vibration and shock as well as noise and luminance, Conclusion The compartment environmental quality of this ambulance is in a good state.
10.Optimization and comparison of extraction methods of mitochondrial DNA of Oncomelania hupensis
Kang WANG ; Shujun XU ; Yixiao WANG ; Wenjie CHEN ; Yinan WANG ; Fenfang YU ; Shaosheng WANG ; Entao SUN ; Shulin ZHOU
Chinese Journal of Schistosomiasis Control 2017;29(2):159-162
Objective To optimize the extraction methods of mitochondrial genome DNA(mtDNA)of Oncomelania hupen-sis. Methods The pyrolysis,protein K variable-temperature digestion and high-concentration potassium acetate purification were applied to optimize the high-concentration-salt precipitation method,and then the optimized method was compared with two common extraction methods,the sucrose density gradient centrifugation method and traditional high-concentration-salt pre-cipitation method. The mtDNA samples were identified by using spectrophotometry,agarose gel electrophoresis and the amplifi-cation products of COX1. The nuclear DNA contamination was tested by the amplification products of ITS. Results The concen-tration and yield of the improved method was significantly higher than those of the traditional method(F=3032.65,10185.00, both P<0.01). The mtDNA samples extracted were essentially free of nuclear DNA and protein,meeting PCR,sequence analy-sis and other molecular biology research requirements. Conclusions The improved high-concentration-salt precipitation meth-od for isolating mtDNA is simple,and it has high yield and low cost. The extracted mtDNA can meet relevant analysis require-ments.