1.Image reconstruction of positron emission tomography
Chinese Journal of Medical Physics 2000;17(4):197-200
As the great progress in computer technology, the image reconstruction of PET has been extensively studied, especially the fast methods being able to suppress the noise and meanwhile improve spatial resolution. This paper gives a brief description of the principle and research status of PET reconstructions, and that of 3D PET as well.
2.Real-time energy correction in digital gamma camera
Chinese Medical Equipment Journal 1989;0(04):-
This paper introduces the generating principle of energy correction table for digital gamma camera and elaborates a method for real-time energy correction. According to the position information of the collected events, correction cells are determined. With the correction value in four adjacent correction cells, coefficient of energy correction is worked out through bilinear interpolation. Finally, real-time energy correction for the collected events is achieved through software programming.
3.Lymphangiogenesis factor in the lymph node metastasis of head and neck cancer
Shujun SUN ; Limin ZHAO ; Jianming ZHOU
Journal of International Oncology 2011;38(7):509-512
Early lymph node metastasis is a common clinical phenomenon in many human cancers, which is associated with both aggressive disease and poor prognosis. Clearly, treatments to specifically block dissemination through the lymphatic network would be desirable either as independent therapies or as adjuncts to existing chemotherapy. At the present stage the target vessels for invasion by lymph-metastasizing tumor cells include preexisting tissue lymphatics abutting the tumor mass through either coincidence or mutual chemoattraction, as well as new lymphatic vessels that proliferate either within or around the tumor as a result of lymphangiogenesis. The lymphangiogenesis is regulated primarily by the lymphangiogenic growth factors VEGF-C and VEGF-D generated by tumor cells or host cells including tissue macrophages. Nevertheless, it remains controversial as to whether this metastasis-enhancing effect simply results from an increase of the number of target vessels due to mitogenesis or from other properties of the newly dividing tumor lymphatics.
4.Research progress of SPARC in esophageal cancer
Haibo HUANG ; Yan ZHAO ; Shujun YANG
Journal of International Oncology 2014;41(12):918-921
Secreted protein acidic and rich in cysteine (SPARC) is expressed in esophageal cancer abnormally.On the one hand,recent studies show that high SPARC expression is correlated with progression and metastasis of esophageal cancer.On the other hand,high SPARC expression increases chemosensitivity and improves short-term efficacy in patients.
5.Betatrophin and glucose-lipid metabolism
Shujun ZHAO ; Mingming WANG ; Shiwei LIU
Chinese Journal of Endocrinology and Metabolism 2015;31(3):288-290
Betatrophin,discovered in 2013,is a protein secreted by liver,white adipose tissues,and brown adipose tissues.Betatrophin can improve glucose tolerance in mice by promoting islet β cell proliferation and increasing the number of β cells significantly and specifically.At the same time,Betatrophin is involved in lipid metabolism.Betatrophin may work as the new target for treatment of diabetes and disorders of lipid metabolism.
6.An epidemiologic analysis of maxillofacial injuries resulted in different causes
Shujun LI ; Yanpu LIU ; Jinlong ZHAO
Medical Journal of Chinese People's Liberation Army 2001;0(08):-
Objective To analyse the characteristics of maxillofacial injuries resulted in different causes. Methods A retrospective review was done of patients admitted to the Stomatology Hospital of Fourth Military Medical University from January, 1996 to July, 2003. Data was grouped by different causes. Results 1 188 patients were reviewed, the majority of victims caused by different causes were males, the ratio of male and female is 3.34∶1. Most industrial and sport injury occurred in men. Traffic accidents were the major cause of the midface fracture and mandibular fracture. While violence was the major cause of pure soft injure and alveolar bone fracture. Conclusions Traffic accidents and violence were the major causes of facial injury. The facial injury caused by traffic accidents, industrial accidents and fall was more serious than those caused by other causes. More emphasis should be put on the prevention and treatment of these injuries to minimize the maxillofacial malformation.
7.Surgical treatment of recurrent gastric carcinoma
Yuting ZHAO ; Zhan SONG ; Shujun ZHANG
Journal of Clinical Surgery 2001;0(03):-
Objective To investigate the surgical indicatin and outcome of recurrent gastric carcinoma.Methods Review the clinical data of 56 cases with recurrent gastric carcinoma underwent reoperation from 1990 to 2000.The operative indication, surgical method and complications were analized.Results In 25 cases the recurrent tumor were resected (44.6%),in 10 cases adjacent organs were resected.NO operative motality was observed.Conclusions More aggressive radical resection of the gastric cancer is the key to prevent recurrence.Laparotomy should be performed without delay once there is a suspicion of recurrence.
8.Relationship between normal weight obesity and cardiovascular risk factors
Hui ZHAO ; Song LENG ; Ying LIU ; Guanghui SUN ; Shujun YU
Chinese Journal of Health Management 2012;06(4):255-258
Objective To determine the relationship between normal weight obesity (NOW) and cardiovascular risk factors.MethodsA total of 940 adults who received a health examination in out hospital were recruited in a cross-sectional study,and 407 with a body mass index (BMI) of18.5 to 25 kg/m2were enrolled for further analysis.Body fat percentage ( BF% ) was measured by bioelectrical impedance analysis (BIA),and the subjects were assigned to the NOW group ( BF% ≥25% for male or BF% ≥35%for female) or the control group ( BF% < 25% for male or BF% < 35% for female).Cardiovascular risk factors and their detection rates were compared between the two groups by using independent sample t test and x2 test.The correlationbetweenNOW and cardiovascular risk factors was assessedbylogistic regression.Results The prevalence of NOW in men and women were13.1% and14.9%,respectively.The prevalence of NOW was increased with age ( x2 =6.90,P <0.05 ).Systolic blood pressure (SBP),diastolic blood pressure ( DBP ),total cholesterol ( TC ),triglycerides ( TG ),low-density lipoprotein cholesterol ( LDL-C) and serum uric acid (SUA) were significantly increased in the NOW group (t values were 2.97,2.44,2.54,5.09,2.71and 3.91,respectively; all P < 0.05 ) ; whereas high-density lipoprotein cholesterol ( HDL-C) was significantly decreased in the NOW group (t =-3.90,P < 0.05 ).The prevalence of hypertension,hyperglycemia,high triglyceride,low HDL-C,dyslipidmia and hyperuricemia was increased in the NOW group in comparison with the control group ( x2 values were 6.76,5.58,14.50,11.97,10.97 and 8.76,respectively;allP< 0.05 ).LogisticregressionshowedNOWincreasedtheriskof hypertension,hyperglycemia,dyslipidmia or hyperuricemia by 2.186,2.120,2.088 or 4.175 times.After adjustment for age and gender,the risk for hyperuricemia was decreased to 3.491,but remained statistically significant higher.Conclusions NOW may be correlated with cardiovascular risk factors,and those with NOW could be at higher risk for cardiovascular diseases.
9.Acute gout attack during upper gastrointestinal bleeding:a report of 186 cases
Jianqiu ZHAO ; Xiangdong LU ; Shujun WEN ; Zhiguang ZHANG
Chinese Journal of General Practitioners 2014;(6):483-484
The clinical data of 186 patients with acute gout attack during upper gastrointestinal bleeding were analyzed retrospectively.The ratio of male to female was 1.7∶1, smokers and alcohol drinkers accounted for 66.1% ( 123/186 ) and 62.4% ( 116/186 ) of patients were had underlying diseases.All patients had different degree of joint painful and fever , the blood uric acid levels were higher.Gastroscopic examinations were performed in 166 patients , of whom 88 cases received endoscopic intervention.The symptoms of gout were improved after treatment with dexamethasone and celecoxib ; and the medication did not induce or increase gastrointestinal bleeding.
10.Relationship between HBV genotype and liver damage in northern China
Shujun GUO ; Juan LI ; Pei QU ; Miaomiao ZHAO ; Shujing SONG
International Journal of Laboratory Medicine 2016;37(6):763-764
Objective To discuss the relationship between hepatitis B virus (HBV) genotype and HBV DNA ,liver fibrosis ,liver function and HBeAg .Methods HBV genotypes ,HBV DNA ,liver fibrosis indicators and alanine aminotransferase(ALT ) ,aspartate aminotransferase(AST ) ,total bilirubin(TBIL) ,albumin(ALB) and HBV e antigen(HBeAg) were detected in patients with serum hepatitis .All data were statistically analyzed .Results There was no significant difference of HBV DNA ,ALT ,AST ,TBIL ,ALB , procollagen- Ⅲ -peptide ,type Ⅳ collagen ,hyaluronic acid and laminin between patients with B and C genotype infection (P> 0 .05) . However ,HBeAg level in patients with C genotype infection was higher than that in patients with B genotype infection (P< 0 .05) . Conclusion There might be no significant difference of HBV DNA ,liver function and liver fibrosis between patients with B and C genotype infection ,but HBeAg level in patients with C genotype infection could be higher than patients with B genotype infection .