Objective:To explore the effect of cognitive-existential group intervention in patients with gastric cancer undergoing chemotherapy after radical gastrectomy.Methods:From September 2020 to September 2021, 80 patients with gastric cancer who received chemotherapy in the Department of Digestive Oncology of the Wuxi Second People's Hospital were selected by the convenient sampling. The patients were divided into the observation group and the control group with 40 cases each by using the random number table. The control group received routine postoperative chemotherapy nursing, while the observation group received cognitive-existential group intervention on the basis of the control group. The intervention effects of the two groups were compared with the Fear of Progression Questionnaire-Short Form (FoP-Q-SF) , Herth Hope Index (HHI) , Distress Thermometer (DT) , and Connor-Davidson Resilience Scale (CD-RISC) .Results:After intervention, FoP-Q-SF and DT scores in the observation group were lower than those in the control group, with statistically significant differences ( P<0.05) . After intervention, HHI and CD-RISC scores in the observation group were statistically higher than those in the control group ( P<0.05) . Conclusions:Cognitive-existential group intervention can effectively reduce the fear of disease progression and psychological pain of gastric cancer patients with chemotherapy after radical gastrectomy, and improve their hope and psychological resilience, which is worthy of clinical promotion.

Calcium oxalate (CaOx) stone is the main type, and its formation is closely related to the metabolism of oxalic acid and calcium. Gut Microbiome is normal microflora which settled in the human intestinal tract and plays an important role in regulating a variety of metabolism in the body. In the past, Oxalobacter formigenes in gut was a protective factor for the formation of CaOx stones. Recently, it has been found that the bacteria regulating oxalate metabolism were not limited to Oxalobacter formigenes. Gut Microbiome of CaOx stones formers is different from healthy people. It regulates the metabolism of oxalic acid in the body through the gut-kidney axis and affect the formation of CaOx stone. The purpose of this study is to describe the characteristics of intestinal flora in patients with CaOx stones, and to summarize its potential function in the formation of CaOx stones and its possible clinical application in the future.

Objective:To explore the effect of core stability training on rehabilitation of patients after lumbar fusion.Methods:From June 2018 to December 2019, 90 patients with lumbar fusion admitted to Wuxi Second Hospital Affiliated to Nanjing Medical University were selected by convenience sampling. The patients were divided into control group and training group according to the method of random number table, with 45 cases in each group. The control group received routine postoperative rehabilitation nursing, while the training group carried out postoperative core stability training nursing. The rehabilitation effects of the two groups were observed.Results:The scores of Numerical Rating Scale (NRS) in the training group were lower than those in the control group at 2, 4, 12 and 24 weeks postoperatively, and the difference were statistical ( P<0.05) . The scores of Oswestry Disability Index (ODI) in the training group 12 and 24 weeks after operation were lower than those in the control group, with statistically significant differences ( P<0.05) . Conclusions:The core stability training nursing is helpful to improve the functional recovery after lumbar fusion, reduce the degree of postoperative pain, and then increase the rehabilitation effect of patients.

Overactive bladder (OAB) is the most bothersome symptom in lower urinary tract symptoms (LUTS). Current pharmacologic treatment aims to inhibit detrusor contraction; however, shows unsatisfied efficacy and high discontinuation rate. LIM kinases (LIMKs) promote smooth muscle contraction in the prostate; however, their function in the bladder smooth muscle remains unclear. Here, we studied effects of the LIMK inhibitors on bladder smooth muscle contraction and proliferation both