At present, chemotherapy combined with radiotherapy or targeted therapy is the key method for the treatment of lymphoma. However, clinical treatment measures are not only effective for patients to obtain disease remission and long-term survival, but also have a negative impact on reproductive function of patients. For young patients with good curative effects, long-term survival and remission, normal childbearing becomes an important aspect of long-term prognosis evaluation of lymphoma, and it is also a concern of lymphoma patients. This article will systematically present the epidemiology of lymphoma, the impact of lymphoma on reproductive function, the status and challenges of reproductive function protection in lymphoma patients, the ethical issues of human reproduction, and the principles and selection of reproductive protection for patients with lymphoma. The analysis and discussion are expected to provide reference for the reproductive protection and eugenics of lymphoma patients in China.