Objective To investigate the epidemic pattern,diagnosis and treatment of schistosomiasis after the 16-years intervention program on its transmissionin Jiaxing region of Zhejiang province.Methods Clinical data of schistosomiasis patients during the last 10 years and pathological specimens with deposited schistosomal eggs during the last 8 years were retrospectively analyzed.Results The total numbers of schistosomiasis patients admitted to hospital increased from 194 in 2001 to 960 in 2010,and from 78 to 266 with complications.Number of the ones with accompanied diseases increased from 116 to 694.All the numbers of the above said three groups showed an yearly increase.The hardest hit age of the patients was between 60 and 74.The number of specimens with deposited schistosomal eggs increased from 192 in 2003 to 298 in 2010.While the ratio of specimens with deposited schistosomal eggs to the total number of pathological specimens became slightly decreasing,the average age of patients increased,Eggs were mainly deposited on appendix,colon,rectum,stomach,liver,gallbladder and small intestine.Conclusion Schistosomiasis still hit the Jiaxing region,with the average age of patients increased.