3.Effect of infiltration anesthesia at Calot's triangle on postoperative analgesia in patients undergoing laparoscopic cholecystectomy: a randomized, controlled, double-blind, clinical trial
Dong ZHANG ; Lihua PENG ; Juying JIN ; Min SHUI ; Su MIN
Chinese Journal of Anesthesiology 2015;35(2):175-177
Objective To evaluate the effect of infiltration anesthesia at Calot's triangle on postoperative analgesia in the patients undergoing laparoscopic cholecystectomy.Methods One hundred and forty patients,aged 18-64 yr,with 18 kg/m2 ≤ body mass index ≤ 31 kg/m2,of ASA physical status Ⅰ or Ⅱ,scheduled for elective laparoscopic cholecystectomy,were randomly divided into 2 groups (n =70 each):control group (group A) and infiltration anesthesia at Calot's triangle group (group B).In group B,1% ropivacaine 10 ml was injected into Calot's triangle before dissection of the gallbladder,while the equal volume of normal saline was injected into Calot's triangle in group A.The patients in both groups received patient-controlled intravenous analgesia (PCIA) for 48 h starting from 10 min before the end of surgery.The VAS score was maintained below 4 during PCIA.When VAS score ≥ 4,lasting for more than 30 min,tramadol 1.5 mg/kg was injected intravenously.The consumption of physic liquor for PCIA,and requirement for tramadol were recorded.The incidence of puncture-related damage to Calot's triangle and local anesthetic intoxication and adverse effects such as nausea and vomiting within 48 h after surgery were also recorded.The first postoperative flatus time was recorded.Results Compared with group A,the consumption of physic liquor for PCIA,requirement for tramadol,and consumption of tramadol were significantly reduced,and no significant change was found in the incidence of nausea and vomiting and the first postoperative flatus time in group B.No puncture-related damage to Calot's triangle occurred in A and B groups.There was no local anesthetic intoxication in group B.Conclusion Infiltration anesthesia at Calot's triangle can optimize postoperative analgesia in the patients undergoing laparoscopic cholecystectomy.
4.Evaluation of red blood cell distribution width, mean platelet volume and cardiac troponin I for early diagnosis of acute coronary syndromes by using ROC curve
Shui FU ; Xianfu JIN ; Miaomiao ZHANG ; Yuan YUAN ; Bangyong CHU
Journal of Chinese Physician 2011;13(5):641-644
Objective To observe the changes of red blood cell distribution width, mean platelet volume and cardiac troponin I in patients with Acute Coronary Syndromes, and to evaluate the value for early diagnosis by using ROC curve. Methods 191 patients with ACS and 206 patients with the chest pain syndromes non-ACS were selected in this study. Electrocardiogram,blood routine,creatinine, LDL-C and cardiac troponin I were determined within six hours after hospitalized,meanwhile the feature of ROC curves was observed. Results There was no significant difference between ACS group and non-ACS group about red blood cell, hemoglobin, platelet,creatinine and LDL-C[(3.82±0.57)×1012/L,(101.3±3.3)g/L,195(98.6-334.8)×109/L,69(45-120)μmol/L,(2.95±0.85)mg/dl vs (3.89±0.50)×1012/L,(103.5±3.7)g/L,201(135.2-346.9)×109/L,71(49-100)μmol/L,(2.82±0.75)mg/dL] (P> 0. 05). Red blood cell distribution width, mean platelet volume and the cardiac troponin I in ACS group[13.70(12.00-15.20)%,9.4(7.42-12.31)fL,(5.63±1.39)μg/L] were significantly higher than that of non-ACS group[12.60(11.20-13.83)%,8.2(6.24-10.97)fL,(0.04.±0.01)μg/L] (P<0.01) .The area under ROC curves of red blood cell distribution width,mean platelet volume and cardiac troponin I were 73.5%, 78.8%, 98.1% respectively, while the best cut-off value was 13.15%, 12.45 fL, 0.06 μg/L respectively. Conclusions The combination using of red blood cell distribution width andmean platelet volume and cardiac troponin I and other conventional cardiac markers might be served as early diagnosis marker for the ACS patients admitted to emergency departments.
5.Diagnostic Value of Serum GP73 Combined with Dickkopf-1 and AFP in Hepatocellular Carcinoma
Fan YAO ; Liang LU ; Liao ZHANG ; Kejia ZHENG ; Shui JIN
Progress in Modern Biomedicine 2017;17(26):5153-5156
Objective:To investigate the diagnostic value of serum GP73 combined with Dickkopf-1 and AFP in hepatocellular carcinoma.Methods:117 cases of hepatocellular carcinoma in our hospital were collected as hepatocellular carcinoma group,80 patients with hepatitis B virus as the hepatitis group,and randomly selected 80 healthy subjects as the control group from September 2014 to September 2016.The serums GP73,Dickkopf-1,AFP level of every group were detected by the enzyme-linked immunosorbent assay (ELISA),and the relationship between the GP73,Dickkopf-1,AFP between clinicopathological features were analyzed,the diagnostic value of GP73,Dickkopf-1 and AFP in hepatocellular carcinoma were analyzed.Results:The serums GP73,Dickkopf-1,AFP level of hepatocellular carcinoma group were higher than those of hepatitis group,control group,and the serum AFP level of hepatitis group was higher than that of control group,the difference was statistically significant (P<0.05).The GP73,Dickkopf-1,AFP in patients with classification B~C were higher than those in classification A among the Child Pugh classification,the difference was statistically significant (P<0.05).No statistical significance on difference of GP73,Dickkopf-1,AFP between different differentiation,tumor size,number of tumors was found (P>0.05).The sensitivity,specificity,positice predictive value,negative predictive value,and accuracy of GP73+Dickkopf-1+AFP in the diagnosis of hepatocellular carcinoma were higher than those of GP73,Dickkopf-1,AFP respectively,the difference was statistically significant (P<0.05).Conclusion:Serums GP73,Dickkopf-1,AFP in patients with hepatocellular carcinoma have high expression levels,combined with the three indicators can obviously improve the diagnostic value of hepatocellular carcinoma,which has clinically important reference value.
6.Changes of Interleukin-18 and Lymphocyte CD_(54) in Children with Congestive Heart Failure
gui-qin, DUAN ; shui-ying, ZHAO ; jin-dou, AN
Journal of Applied Clinical Pediatrics 2006;0(18):-
Objective To discover the role of interleukin-18(IL-18) and CD_(54) in congestive heart failure(CHF),and evaluate the diagnostic value of IL-18 and CD_(54) in CHF.Methods Blood samples were collected from 52 children with CHF,included 18 cases in classⅡ,17 cases in class Ⅲand 17 cases in class Ⅳ.Fifteen healthy children were normal control group.The levels of IL-18 was(detec-)ted by ELISA method and the expression of CD_(54) was examined by flow cytometry.Results The levels of IL-18 and CD_(54) in CHF were significantly higher than those of control subjects(P0.05),but the levels were respectively significantly higher than that of control subjects(P
7.Design of the mobile clinical information system based on PDA.
Chinese Journal of Medical Instrumentation 2005;29(6):414-418
This paper is based upon a certain hospital's Mobile Clinical Information System. It discusses the design of the system in detail from three aspects: its function, its framework and the selection of its software and hardware. Finally some discussions are made for its improvement and perfection. PDA (personal digital assistant), clinical information, wireless network
Hospital Information Systems
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Microcomputers
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Software Design
8.Study on classification and coding for public health information.
Li-hua LIU ; Shui-gao JIN ; Jing GUO
Chinese Journal of Preventive Medicine 2007;41(5):344-347
OBJECTIVETo improve data unified descriptions, identification, query and management in public health service by means of establishing public health information classification framework and coding system.
METHODSData sets created from all fields in public health, scientific research, health management were classified into four layers of frameworks primary class, sub-class, main class and subject areas by means of integration of vertical with horizontal classifications. All these classes were further abstracted, merged and coded by individual characteristics in public health systems.
RESULTS(1) 4 subject areas in diseases control and prevention, public health service, public health management and sanitation surveillance were established including a total of 18 main classes, 49 sub-classes and 205 primary classes. (2) 7 digits and 4 segments (area code, code, disease classification code) were designed including a total of 30 digits multi-classification codes. The purpose of data effectively classifying and coding by application of 50 basic data sets in 9 areas fo public health has been realized.
CONCLUSIONWe believe that this method is of efficiency in data classification and code for public health information communication.
Healthcare Common Procedure Coding System ; Public Health Informatics ; classification ; statistics & numerical data
9.Expression and role of TLR and SOCS mRNA in newborn infants.
Lin WANG ; Jian-bo XU ; He-shui WU ; Jin-xiang ZHANG ; Yuan TIAN
Chinese Journal of Pediatrics 2006;44(8):621-622
Cells, Cultured
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Enzyme-Linked Immunosorbent Assay
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Female
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Fetal Blood
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Humans
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Infant, Newborn
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Lipopolysaccharides
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Lymphocytes
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metabolism
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Male
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RNA, Messenger
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metabolism
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Reverse Transcriptase Polymerase Chain Reaction
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Suppressor of Cytokine Signaling 1 Protein
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Suppressor of Cytokine Signaling 3 Protein
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Suppressor of Cytokine Signaling Proteins
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genetics
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metabolism
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Time Factors
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Toll-Like Receptor 2
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genetics
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metabolism
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Toll-Like Receptor 4
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genetics
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metabolism
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Tumor Necrosis Factor-alpha
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metabolism
10.Value of contrast-enhanced ultrasound in the diagnosis of postnatal placenta increta
Yan JIAO ; Guifeng LIN ; Xujuan SHUI ; Yaping ZHAO ; Huipei JIN ; Chao ZHANG ; Yan YANG
Chinese Journal of Ultrasonography 2011;20(8):692-695
Objective To investigate the clinical value of contrast-enhanced ultrasound(CEUS) in the diagnosis of postnatal placenta increta. Methods Twenty-six patients with postnatal placenta increta were examined by gray-scale and color Doppler ultrasound and CEUS. Then microvascular perfusion and enhanced features of lesions, myometrium and serous layer were observed. Arriving time (AT), time to peak intensity (TTP) and the lasting time of enhancement (LTE) were recorded. AT,TTP and LTE of enhanced lesions were compared with those of normal myometrium. Results Serous layer, lesions and adjcent myometrium,normal myometrium enhanced in turn. There was no obvious boundary between the lesions enhanced and adjcent myometrium. AT and TTP of the lesions enhanced were both less than those of normal myometrium ( P <0. 05). LTE of the part of lesions enhanced was more than that of normal myometrium ( P <0.05).Part of lesions never enhanced during the whole process. The serous layer of uterine was smooth and uninterrupted in 24 patients. These 24 patients all recovered after conservative treatment. The local serous layer adjcent lesions was not smooth, but no contrast agent leakage occurred in another 2 patients, and uterine lobectomy were performed in emergency because of massive hemorrhage during conservative treatment. Conclusions Microvascular perfusion and enhanced features of lesions,myometrium and serous layer could be showed clearly through CEUS.