1.Blarmonious society calls for health manggement
Chinese Journal of Hospital Administration 2008;24(9):626-628
Health management is the intrinsic requirement to build and embody a harmonious society. While health management provides strong human resources for the development of a harmonious society, a harmonious society promotes the health management. Health management plays a significant role in the construction and development of a harmonious society in terms of reducing risks to the health, improving the quality of life, lowering medical cost, lightening the socio-medical burden, enhancing awareness of health, improving the national health conditions, protecting health resources, and promoting a sustainable social development. Health is an important component of social productive forces, and health management is an essential prerequisite for the harmonious development of society. There would be no real harmonious society without effective health management.
2.Hinokitiol induces clear cell renal cancer 786-O cell apoptosis via autophagy induction
Xiaochen NI ; Zhihong ZHAO ; Yongliang MA ; Zongtao REN ; Bin LIU ; Bo FAN ; Shufei WEI ; Aili ZHANG
Chinese Journal of Clinical Oncology 2015;(1):43-46
Objective: To investigate the effects of hinokitiol on the proliferative inhibition and apoptosis induction in human clear cell renal cancer 786-O cells. Methods:CCK-8 assays were performed to analyze the effects of hinokitiol on the proliferation of 786-O cells. The apoptosis rate was determined by flow cytometry. EGFP-LC3 microscopy assays were performed to assess the autoph-agy flux. Cleaved Caspase-3, LC3, and P62 were detected by Western blot. Results: Hinokitiol could inhibit the proliferation of the 786-O cells and could induce cell apoptosis via Caspase pathway. Hinokitiol induced the autophagy of 786-O cells, increased LC3 ex-pression, and downregulated P62 expression. Conclusion: Hinokitiol can inhibit the proliferation of 786-O cells and can induce cell apoptosis via autophagy induction.