Objective:To investigate the incidence of complications related to thread lift in the treatment of facial rejuvenation.Methods:The databases of China National Knowledge Infrastructure (CNKI), VIP Chinese Science and Technology Journal Full-text Database (VIP-CSJFD), Wanfang Data, China Biology Medicine (CBM), PubMed, The Cochrane Library and Embase were searched from database establishment to April 20, 2022. The inclusion and exclusion criteria were developed to include relevant studies that met the criteria. Two investigators independently performed literature screening and data extraction; the STROBE statement scored the quality of inclusion criteria for cross-sectional studies, the total score was 0-22 points, and the research of which score >11 points was considered as high-quality research; data analysis was performed using Stata16.0 software; Egger test and funnel plot analysis were used to evaluate the publication bias of literature.Results:Thirty-three articles involving 8 919 patients were included in this meta-analysis. The quality scores of 28 articles were > 11 points, and the remaining 5 articles were exactly 11 points, indicating that the overall quality of the articles was acceptable. The outcome measures of this meta-analysis included 11 indicators such as paresthesia, infection, facial asymmetry, facial nerve injury, mild unevenness or irregular contour, postoperative allergy, postoperative hematoma, pain, wire exposure or visibility, bruising, and swelling. The complication rates for each outcome measure were: paresthesia (1%), infection (0), facial asymmetry (2%), facial nerve injury (0), mild unevenness or contour irregularity (7%), postoperative allergy (0), postoperative hematoma (0), pain (17%), exposed or visible wire (7%), bruising (28%), swelling (55%). Egger test and funnel plot analysis showed that there was no publication bias in sensory abnormalities, facial asymmetry, postoperative allergy and pain. There may be some publication bias in the other 7 indicators.Conclusion:Among the complications related to thread lift, postoperative swelling, pain and bruising are the most common, while the incidence of serious complications is rare. Most complications are transient and self-resolving, and in general, thread lift is a relatively safe treatment modality.

Objective:To investigate the incidence of complications related to thread lift in the treatment of facial rejuvenation.Methods:The databases of China National Knowledge Infrastructure (CNKI), VIP Chinese Science and Technology Journal Full-text Database (VIP-CSJFD), Wanfang Data, China Biology Medicine (CBM), PubMed, The Cochrane Library and Embase were searched from database establishment to April 20, 2022. The inclusion and exclusion criteria were developed to include relevant studies that met the criteria. Two investigators independently performed literature screening and data extraction; the STROBE statement scored the quality of inclusion criteria for cross-sectional studies, the total score was 0-22 points, and the research of which score >11 points was considered as high-quality research; data analysis was performed using Stata16.0 software; Egger test and funnel plot analysis were used to evaluate the publication bias of literature.Results:Thirty-three articles involving 8 919 patients were included in this meta-analysis. The quality scores of 28 articles were > 11 points, and the remaining 5 articles were exactly 11 points, indicating that the overall quality of the articles was acceptable. The outcome measures of this meta-analysis included 11 indicators such as paresthesia, infection, facial asymmetry, facial nerve injury, mild unevenness or irregular contour, postoperative allergy, postoperative hematoma, pain, wire exposure or visibility, bruising, and swelling. The complication rates for each outcome measure were: paresthesia (1%), infection (0), facial asymmetry (2%), facial nerve injury (0), mild unevenness or contour irregularity (7%), postoperative allergy (0), postoperative hematoma (0), pain (17%), exposed or visible wire (7%), bruising (28%), swelling (55%). Egger test and funnel plot analysis showed that there was no publication bias in sensory abnormalities, facial asymmetry, postoperative allergy and pain. There may be some publication bias in the other 7 indicators.Conclusion:Among the complications related to thread lift, postoperative swelling, pain and bruising are the most common, while the incidence of serious complications is rare. Most complications are transient and self-resolving, and in general, thread lift is a relatively safe treatment modality.

Hypermetabolism and insulin resistance are prominent features of trauma including burn injury, surgery, and infection. Hypermetabolism results in insufficiency in energy supply, which induces organ function lesion, immune suppression, high infection rate, and wound healing delay, thus exerting a strong impact on patients' quality of life and prognosis. The molecular mechanism in the occurrence and development of hypermetabolism is very complicated, and it has not been fully elucidated. Recently, brown adipose tissue (BAT) was found to be present not only in rodents but also in humans, and its activity was associated with resting metabolic rate. BAT may become the new target of research in prevention and control of metabolic disorder.
Adipose Tissue, Brown ; metabolism ; Animals ; Burns ; metabolism ; Energy Metabolism ; Humans ; Insulin Resistance ; Quality of Life