OBJECTIVE:To evaluate the utilization of human serum albumin in a hospital.METHODS:The utilization of human serum albumin in a hospital in the first quarter of 2006 was reviewed analytically using hospital computer database system.RESULTS:Human serum albumin was used in 55 departments for 17 categories of diseases,mainly for critical patients,with a common individual consumption quantity ranged from 10 g to 20 g.Most(51.10%) of the patients used this drug on account of hypoproteinemia,and most of them had a baseline serum albumin level at 21～30 g?L-1 before using human serum albumin.CONCLUSION:Human serum albumin was used extensively in the hospital.But its use is sometimes irrational because some physicians didn't familiarize the real indications for using human albumin,which should be intervened urgently.

Objective To evaluate the value of PLD associated with O 3 injection for the treatment of lumbar disc heniation.Methods Lateral decubitus position on healthy side under the direction of DSA, a working pipe was inserted from the back lateral way to damage the disc contents through multiple angles followed by extirpation of the nucleus pulposus and then injecting O 2-O 3 10 ml into the lumbar disc space and near by area of the inter vertebral foramina. As for patients with L4-5 and L5-S1 protrusions the main lumbar discs can be treated in the same way, but for another minor one, the injection of O 2-O 3 10 ml into the lumbar disc and the nearby intervertebral foramina and ethanol through a 21G needle would be properly promising. Results Puncture and technical opertaion were performed successfully in all the patients with excellent results in 63, good in 27, and poor in 10. 120 cases with injection of O 2-O 3 into the lumbar discs showed the figure of lumbar space displaying clear in 37 cases, less clear in 35 cases, only gas entering lumbar disc at the needling point with lumbar space displaying unclear in 30 cases and lots of gas entering the front space of canalis vertebralis cavitas epiduralis in 18 cases. Conclusions PLD associated with O 3 injection is the advantageous supplement mutually posscessing safety and efficancy.

Objective To explore the effects of early food intake on recovery of patients with postoperative upper urinary tract. Methods One hundred and twenty-six patients after upper urinary tract surgery from January to December 2012 were divided into early food intake group ( food intake beginning 6 h after surgery) and conventional group ( food intake began after first flatus ) . The recovery time of gastrointestinal function, hospital stay, drainage volume and other parameters in two groups were compared. Results The time of flatus, leaving the sickbed, defecation, stopping transfusion and getting right time of eating were (1. 80 ± 0. 46), (1. 45 ± 0. 51), (4. 06 ± 1. 10), (3. 27 ± 0. 85), (3. 33 ± 1. 16) d in the early food intake group better than those of the conventional group (t=3. 598, 2. 239, 4. 722, 3. 140, 3. 395;P<0. 05). Conclusions Early food intake after surgery of upper urinary tract can promote recovery of gastrointestinal function and decrease fluid infusion and hospital stay.

Objective To evaluate the efficacy difference of different embolization agents in transcatheter embolization for treating massive hemoptysis caused by systemic pulmonary circulation shunt(SPS). Methods The clinical and imaging data in 98 patients with hemoptysis complicating SPS,including bronchodilator in 72 cases,pulmonary tuberculosis in 18 cases and lung carcinoma in 8 cases. All cases were treated with bronchial arterial embolization (BAE). According to different used embolization agents, the cases were divided into the gelfoam group and polyvinyl alcohol(PVA)grains embolization group. All cases were followed up at postoperative 1 d,1,3,6 months as well as 1,2 years. The data were analyzed by using Ridit test. Results Ninety-eight cases of massive hemoptysis were confirmed by DSA,among them,84 cases were complicating pulmonary artery fistula, 18 cases were pulmonary venous fistula and 2 cases were mixed fistula; 32 cases were simple BPS, 62 cases were pulmonary circulation fistula existed in the bronchial arteries and non-bronchial artery and 4 cases were simple non-BPS. The two groups had no complications such as embolism,paraplegia,esophagus-trachea fistula and skin ischemic necrosis. The follow up on postoperative 1 d, at postoperative 1, 3,6 months and at postoperative 1,2 years indicated that among 48 cases in the gelfoam group, 20 cases were cured, 18 cases were significantly effective,6 cases were effective and 4 cases were ineffective,the effective rate was 91.7 % ;among 50 cases in the PVA grain embolization group, 38 cases were cured, 8 cases were significantly effective,4 cases were effective and O case was ineffective, the effective rate was 100%. Moreove no severe complications such as ectopic embolism, paraplegia, esophagus-trachea fistula and skin ischemic necrosis occurred. The difference between the two groups had statistical significance by Ridit analysis. Conclusion Transcatheter embolization for treating massive hemoptysis caused by SPS is safe and reliable,has small trauma, using PVA grains embolization can reduce the long term recurrence rate of hemoptysis.

Objective? To understand the situation of urinary incontinence and quality of life among patients with post-laparoscopic radical prostatectomy and to analyze the correlation between them. Methods? From September 2015 to October 2016, we selected 115 patients with post-laparoscopic radical prostatectomy at a ClassⅢ Grade A hospital in Beijing for survey by questionnaire with the method of convenience sampling. We collected patients' general information as well as disease information, and evaluated the situation of urinary incontinence (incidence and severity of urinary incontinence) with the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) and influence of urinary incontinence on quality of life with the Incontinence Impact Questionnaire (IIQ-7) to analyze the correlation between severity of urinary incontinence and quality of life. Results? Among 115 patients with post-laparoscopic radical prostatectomy, there were 95 (82.6%) urinary incontinence patients including 41 cases (43.1%) with mild urinary incontinence, 47 cases (49.5%) with medium urinary incontinence and 7 cases (7.4%) with severe urinary incontinence. The score of severity of urinary incontinence ranged from 0 to 19.0 with 8.0 for the median and 5.0 for the interquartile range. Spearman correlation analysis showed that the score of IIQ-7 had a positive correlation with the severity of urinary incontinence (r=0.674, P＜0.01), and had a negative correlation with the postoperative time (r=-0.215, P＜0.05). Multiple linear regression analysis showed that the main influencing factor of quality of life was severity of urinary incontinence (P＜0.01). Conclusions? Urinary incontinence is common among patients with post-laparoscopic radical prostatectomy mainly in mild and medium urinary incontinence. The more serious the urinary incontinence is,the greater the influence on quality of life is which points out that the scientific and effective management by medical staff for urinary incontinence can improve patients' quality of life.

OBJECTIVE：To establish a method for the content determination of to tal flavonoids from Amomum tsao-ko ，and to optimize the purification technology by macroporous resin. METHODS ：The content of total flavonoids was measured by HPLC. The determination was performed on Eclipse Plus C 18 column with mobile phase consisted of acetonitrile- 1％ acetic acid solution （15∶85，V/V）at the flow rate of 0.8 mL/min. The column temperature was 40 ℃，and the detection wavelength was set at 256 nm. The sample size was 10 μL. Taking the adsorption and desorption performance as indexes，6 kinds of macroporous resins were screened out by static adsorption and desorption tests ；adsorption and desorption time were investigated by static adsorption and desorption kinetics tests. Using the content of total flavonoids （calculated by rutin ）as index ，with sample concentration ，sample pH，ethanol volume fraction and elution amount as factors ，based on single factor test ，orthogonal design was used to optimize the purification technology of total flavonoids from A. tsao-ko ，and validation test was performed. RESULTS ：The linear range of rutin were 0.028-0.281 mg/mL（r＝0.999 9）. The limit of quantification was 437.5 ng/mL and the limit of detection was 109.4 ng/mL. RSDs of precision ，stability and reproducibility tests were all lower than 2％；the recoveries were 96.24％-99.75％（RSD＜2％，n＝ 6）. The comprehensive capacity of adsorption and desorption of HPD 450 macroporous resin was the most suitable ，and the best static adsorption and desorption time both were 12 h. The optimal purification technology was 1.854 4 mg/mL ； ethanol elution was 8 times of the column volume. Vertificationtests show that after optimized ，the content of total flavonoids from A. tsao-ko increased from 22.556 7 mg/g to 57.728 2 mg/g. The purity of was 2.56 and stable for the content determination. Optimal purification technology is stable and feasible ，which is suitable for purifieation of total flavonoids from A. tsao-ko .