1.Research progress on neuroprotective effect and mechanism of spermidine
Chaoyong WANG ; Deyan CHEN ; Shuangshi WU ; Binjia RUAN ; Wanda ZHAN ; Fanhao WEI ; Yongxiang WANG
Journal of Clinical Medicine in Practice 2024;28(2):124-128
Spermidine,as a natural polyamine with high content in nerve cells,plays roles in regulating synaptic plasticity,promoting autophagy,and alleviating oxidative stress in the nervous sys-tem.Spermidine and polyamine metabolism may bring new therapeutic ideas for nervous system injury diseases.This paper reviewed the neuroprotective effects and mechanisms of spermidine in nervous sys-tem injury diseases.
2.Research progress on neuroprotective effect and mechanism of spermidine
Chaoyong WANG ; Deyan CHEN ; Shuangshi WU ; Binjia RUAN ; Wanda ZHAN ; Fanhao WEI ; Yongxiang WANG
Journal of Clinical Medicine in Practice 2024;28(2):124-128
Spermidine,as a natural polyamine with high content in nerve cells,plays roles in regulating synaptic plasticity,promoting autophagy,and alleviating oxidative stress in the nervous sys-tem.Spermidine and polyamine metabolism may bring new therapeutic ideas for nervous system injury diseases.This paper reviewed the neuroprotective effects and mechanisms of spermidine in nervous sys-tem injury diseases.