1.Preliminary study of cerebral venous oxygen saturation in healthy people using MR quantitative susceptibility mapping
Chao ZUO ; Chao CHAI ; Shuang XIA
Chinese Journal of Radiology 2016;50(9):652-656
of left and right side cerebral cortical veins was 159.16(154.88-164.13)ppb(× 10-9), 164.61(156.23-168.04) ppb, respectively. The median susceptibility (extent) of left and right side thalamostriate veins was 160.51 (152.14-170.06) ppb, 162.48(153.47-173.66)ppb, respectively. Left were less than the right, and the difference was statistically significant (Z=-3.14,-2.02, P<0.05). And the difference of two side of other cerebral venous susceptibility had no statistical significance. The median susceptibility (extent) of right cerebral cortical veins, left thalamostriate veins and right septal veins of 22 male was 166.22(159.21-169.99) ppb, 168.65(159.19-174.45)ppb and 153.42(148.10-161.78)ppb, respectively. The coresponding positions of median susceptibility (extent) of 38 female was 161.10(155.06-167.15)ppb, 157.70(151.53-164.41)ppb and 147.52(142.94- 154.16)ppb, respectively. The susceptibility of right cerebral cortical vein, left thalamostriate vein, right septal vein of male was significantly different from the females (Z=-2.03,-2.20,-2.33, P<0.05). Futhermore, we also found that there had positive correlation between age and right thalamostriate vein(r=0.28,P<0.05). Conclusion The magnetic sensitive of the right thalamostriate vein tends to increase along with the age, and some of peoples had difference with bilateral and age.
3.Comparison between Radiofrequency Coblation and CO2 Laser for the Treatment of Early Glottic Carcinoma
Yu SHUANG ; Chao LI ; Yongwang HUANG ; Shuang WU
Journal of Audiology and Speech Pathology 2015;(4):372-376
Objective To comparison curative effects between radiofrequency coblation and CO 2 laser in treat‐ment of early glottic carcinoma .Methods A total of 104 patients with early glottic cancer (Tis ,T1a ,T1b ) were treated in our department from October 2007 to December 2012 .Among them 64 cases underwent radiofrequency ablation (radiofrequency group) while 40 cases underwent CO2 laser resection (CO2 laser group) .The operation time and the postoperative pain VAS scores were recorded .All of the patients were examined by electronic laryngoscopy and a‐coustic analysis in 1 week ,1 month ,3 months after surgery .Results The mean operation time of radiofrequency group was 8 .75 ± 1 .62(min)and CO2 laser group was 11 .82 ± 1 .51(min) .The radiofrequency group was better than CO2 laser group(P < 0 .05) .The differences of postoperative pain VAS score was not statistically significant be ‐tween radiofrequency group(2 .79 ± 0 .47) and CO2 laser group (2 .96 ± 0 .64)(P> 0 .05) .The mucosal recovery of radiofrequency group in 1 month after surgery was better than the CO2 laser group (χ2 = 13 .842 ,P< 0 .05) .Subjects in radiofrequency group and CO2 laser group showed statistical significance and linear trends in jitter ,shimmer ,HNR over time by univariate test of repeated measurement ANOVA (P < 0 .05) .The differences of acoustic parameters (jitter ,shimmer ,HNR)between radiofrequency group and CO 2 laser group were statistically significant by multiva‐riate test of repeated measurement ANOVA (P< 0 .05) .The differences of 3 - years survival rate ,local recurrence rate ,recurrence rate with anterior commissure involved and postoperative adhesion rate with anterior commissure in ‐volved were not statistically significant between radiofrequency group and CO 2 laser group (P > 0 .05) .All of the patients had not underwent tracheotomy .They did not have cough ,dyspnea ,severe pain ,hemoptysis ,serious compli‐cations after surgery .Conclusion Both radiofrequency coblation and CO 2 laser are safe and effective surgical meth‐ods in the treatment of early glottic carcinoma .The operation time of radiofrequency coblation is shorter than CO 2 laser surgery .The mucosal recovery in 1 month after surgery and acoustic recovery of radiofrequenay coblation are all better than that of the CO2 laser surgery .
7.Imaging findings and clinical manifestations of pelvic lipomatosis:a report of 3 cases
Chao CHAI ; Qian JI ; Shuang XIA ; Lixiang HUANG ; Wen SHEN
Chinese Journal of General Practitioners 2014;(6):489-492
The imaging findings of pelvic lipomatosis as confirmed by operation and pathology were examined in 1 case and two follow-up asymptomatic cases retrospectively analyzed.The imaging findings included a compressed and deformed bladder with a superior displacement.Its shape was like an inverted tear and pear in coronal view and a banana in sagittal view.Bilateral ureters were both compressed with a medial deviation.And bilateral ureters were dilated with hydronephrosis in 1 case.Rectum and sigmoid were both compressed and became narrowed.The clinical manifestations included frequent urination , urgent urination , urination pain, dysuria, constipation, nausea, vomit and fever in 1 case while another 2 cases stayed asymptomatic.
8.Investigation on level of DDT accumulation in women and children of a polluted area.
Shuang LI ; Chao-lin LI ; Yan-rang WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2010;28(5):353-355
Adult
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Child
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DDT
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analysis
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blood
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Environmental Pollution
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prevention & control
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Female
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Humans
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Male
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Milk, Human
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chemistry
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Young Adult
9.Detection of expressions of Ck2α,β-catenin and survivin in ovarian cancer tissue and its clinical application value
Shuang WU ; Yimeng LIU ; Chao LIU ; Lin GUO ; Jianying XIAO
Journal of Jilin University(Medicine Edition) 2014;(6):1256-1260
Objective To study the expressions of casein kinase 2α(Ck2α),β-catenin, survivin in ovarian cancer tissue and analyze the relationships between them, and to explore the clinical application value. Methods Immunohistochemistry staining was used to detect the expressions of Ck2α,β-catenin and survivin in 8 cases of simple ovarian cysts tissue,8 cases of ovarian benign tumor tissue and 29 cases of ovarian cancer tissue;the correlations of the expressions of Ck2α,β-catenin,survivin in ovarian cancer tissue and their associations with the clinicopathologic characteristics were analyzed.Results The expression levels of Ck2α,β-catenin and survivin in ovarian cancer tissue were significantly higher than those in simple ovarian cysts tissue and ovarian benign tumor tissue(P<0.05);the Ck2αexpression level in ovarian cancer tissue was positively corelated with the expression levels ofβ-catenin and survivin(r=0.438,r=0.479,P<0.05);the expression levels of Ck2α,β-catenin and survivin in low-medium differentiation group were significantly higher than those in high differentiation group (P<0.05);the expression levels of Ck2α,β-catenin and survivin in stagesⅡandⅢ group were significantly higher than those in stage Ⅰ group(P<0.05).Conclusion The protein expression levels of Ck2α,β-catenin and survivin are increased in ovarian cancer tissue, and three are positive corelations between them;Ck2α,β-catenin and survivin may play an important role in the occurrence and development of ovarian cancer;the combined detection of them has important clinical value.
10.Thrombocytopenia in pregnancy and neonatal outcomes.
Shuang CHAO ; Chao-Mei ZENG ; Jie LIU
Chinese Journal of Contemporary Pediatrics 2011;13(10):790-793
OBJECTIVETo study the relationship between thrombocytopenia in pregnancy associated with various causes and neonatal outcomes.
METHODSMedical records of 140 pregnant women with thrombocytopenia in pregnancy and the neonatal outcomes from January 2009 to December 2010 were reviewed retrospectively. The pregnant women were classified into four groups according to the causes of thrombocytopenia: gestational thrombocytopenia (GT; n=94), pregnancy with immune thrombocytopenic purpura (ITP; n=30), pregnancy with other hematological disease (aplastic anemia or myelodysplastic syndrome; n=12), and other causes (n=4): pregnancy induced hypertension syndrome, pregnancy with systemic lupus erythematosus, and pregnancy with alcoholic cirrhosis. The neonatal outcomes in the four groups were compared.
RESULTSThe premature birth rates in the GT and the ITP groups were 11.3% and 16.7%, respectively. There was no significant difference between the two groups. The premature birth rate in the other hematological disease group was 53.8%, which was significantly higher than that in the GT (P<0.01) and the ITP groups (P<0.05). Congenital passive immune thrombocytopenia was found in 2 neonates (2%) in the GT group and in 4 neonates (13%) in the ITP group (P<0.05). In addition, other diseases were also observed in neonates in the ITP group, including 1 case (3%) of ITP and 1 case (3%) of Evans syndrome. Intracranial hemorrhage occurred in one neonate (8%) in the other hematological disease group. Neonatal lupus syndrome was found in 1 case (25%) in the other causes group.
CONCLUSIONSThrombocytopenia in pregnancy associated with different causes may result in different neonatal outcomes.
Adult ; Female ; Humans ; Infant, Newborn ; Pregnancy ; Pregnancy Complications, Hematologic ; Pregnancy Outcome ; Premature Birth ; epidemiology ; Prognosis ; Retrospective Studies ; Thrombocytopenia ; complications ; drug therapy