1.Improvement of Digital Capsule Endoscopy System and Image Interpolation.
Shaopeng ZHAO ; Guozheng YAN ; Gang LIU ; Shuai KUANG
Chinese Journal of Medical Instrumentation 2016;40(1):27-37
Traditional capsule image collects and transmits analog image, with weak anti-interference ability, low frame rate, low resolution. This paper presents a new digital image capsule, which collects and transmits digital image, with frame rate up to 30 frames/sec and pixels resolution of 400 x 400. The image is compressed in the capsule, and is transmitted to the outside of the capsule for decompression and interpolation. A new type of interpolation algorithm is proposed, which is based on the relationship between the image planes, to obtain higher quality colour images. capsule endoscopy, digital image, SCCB protocol, image interpolation
Algorithms
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Capsule Endoscopy
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instrumentation
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Equipment Design
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Image Processing, Computer-Assisted
2.Studies on chemical constituents of Bidens bipinnata Ⅰ
Shuai LI ; Haixue KUANG ; Yoshihito OKADA ; Tor OKUYAMA
Chinese Traditional and Herbal Drugs 1994;0(09):-
Object To study the chemical constituents in Bidens bipinnata L Methods Isolation and purifica tion were carried out on silica gel, ODS column and HPLC; the chemical constitue nts were identified by physico-chemical properties and structurally elucidated by spectral analysis Results From EtOAc extract of B bipinnata, eight compounds were obtained and identified as: salicyl i c acid (Ⅰ), 9, 12, 13-trihydroxy-10, 15-octadecadienoic acid (Ⅱ), 9, 12, 13-trihydroxy-10-octadecaenoic acid (Ⅲ), benzyl O-?-D-glucopyranoside (Ⅳ), benzen ethyl O-?-D-glucopyranoside (Ⅴ), (Z)-3-hexenyl O-?-D-glucopyranoside (Ⅵ), eugenyl O-? -D-glucopyranoside (Ⅶ), 3-methyl-2-(2-pentenyl)-4-O-?-D-glucopyranosyl-△ 2-cyclopenten-1-one (Ⅷ) Conclusion All of these compounds, with the exception of Ⅰ, are obtained from the plant for the first time
3.Chemical constituents of Bidens bipinnata (Ⅱ)
Shuai LI ; Haixue KUANG ; Okada YOSHIHITO ; Toru OKUYAMA ;
Chinese Traditional and Herbal Drugs 1994;0(09):-
Object To study the chemical constituents of Bidens bipinnata L Methods Isolation and purification were carried out on silica gel, ODS column, and Sephadex LH 20, HPLC, identified by physicochemical properties and structurally elucidated by spectral analysis Results From n BuOH extract of B bipinnata, 12 compounds were obtained and identified as: 6 O ? D glucopyranosyl 6, 7, 3′, 4′ tetrahydroxyaurone (Ⅰ), 6 O (6″ acetyl ? D glucopyranosyl) 6, 7, 3′, 4′ tetrahydroxyaurone (Ⅱ), quercetin 3 O ? D glucopyranoside (Ⅲ), quercetin 3 O ? L rhamnoside (Ⅳ), iso okanin 7 O ? D glucopyranoside (Ⅴ), esculin (Ⅵ), (E) 2 hexenyl O ? D glucopyranoside (Ⅶ), n hexyl O ? D glucopyranoside (Ⅷ), isopentyl O ? D glucopyranoside (Ⅸ), n butyl O ? D fructofuranoside (Ⅹ), n butyl O ? D fructofuranoside (Ⅺ), n butyl O ? D fructopyranoside ( ⅩⅡ ) Conclusion All of these compounds, except Ⅰ and Ⅴ, are obtained from the plant for the first time
4.A method for bleeding detection in endoscopy images using SVM.
Wenming XU ; Guozheng YAN ; Zhiwu WANG ; Gang LIU ; Shuai KUANG ; Shaopeng ZHAO
Chinese Journal of Medical Instrumentation 2015;39(1):9-12
Because the huge number of images of the digestive tract by Wireless Capsule Endoscopy (WCE) are left to the medical personnels detected by their eyes, huge burden leaves to doctors. This article provides a classification of method based on SVM (Support Vector Machine) for the capsule endoscopy bleeding intelligent recognition. We created a new kind of feature parameter, and the experiment result can reach 83% specificity and 94% sensitivity.
Capsule Endoscopy
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Gastrointestinal Tract
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pathology
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Hemorrhage
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diagnosis
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Humans
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Sensitivity and Specificity
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Support Vector Machine
5.The development status and analysis of Traditional Chinese Medicine in Indonesia
Kuang SHUAI ; Yaqian YIN ; Aun Choo NEOH ; Jing ZHAO ; Longhui YANG ; Kakit HUI ; Hongxin CAO
International Journal of Traditional Chinese Medicine 2021;43(4):318-323
Indonesia is an island country in Southeast Asia. In 2014, Indonesia established the National Health Insurance System (NHIS), and until 2019, the NHIS hadcovered 82% residents. The leading causes of death in Indonesia were stroke, ischemic heart disease, diabetes, tuberculosis and cirrhosis. In 1996, the Indonesian Ministry of Health allowed acupuncturists to enter Indonesian medical institutions to practice acupuncture. After that acupuncture was included in college education as a major course. However, there are still some problems, such as insufficient policy and legislation support of Traditional Chinese Medicine (TCM), imperfect education and talent training system of TCM, and low acceptance of TCM theories. Therefore, it is recommended that the local societies and organizations could actively promote the government’s legislation on TCM; local TCM schools could build a team of excellent teachers, improve teaching quality, and cultivate local TCM talents; strengthen the cooperation and exchanges of traditional medicine between the two countries to promote the spread and development of TCM in Indonesia.
6.Multi-center clinical trial of Rongxin Pills in treating viral myocarditis in children with deficiency of both qi and yin and heart meridian stasis syndrome
Shuai FAN ; Hong CUI ; Siyuan HU ; Hong LIU ; Jie SHEN ; Xianchun DING ; Honghua KUANG ; Shunyi SONG ; Wei ZHANG
Drug Evaluation Research 2017;40(1):68-74
Objective To observe Rongxin Pills in the treatment of viral myocarditis in children (deficiency of both qi and yin and heart meridian stasis syndrome) and the effectiveness and clinical application of safety.Methods Viral myocarditis patients (280 cases,deficiency of both qi and yin and heart meridian stasis syndrome),according to 3:1 ratio as the test group (n =21 0) and control group (n =70).The test group took orally Rongxin pills each time 4.5~9 g,3 times daily;the control group oral coenzyme Q10 capsule each time 10 ~ 20 mg,twice daily.The course of treatment was 28 d.The experiment was carried out with the random and double blind method.The symptoms of myocarditis,integrated and electrocardiogram,echocardiography,myocardial enzymes,as well as the efficacy of traditional Chinese medicine and improvement of the effect of the disease were observed.Results The results of FAS (PPS) analysis showed that 28 d after treatment,the symptom score and mean of experimental group and control group were 5.975 (6.000) and 4.721 (4.788).The syndromes of the total effective rates were 91.62% (90.59%) and 70.59% (71.21%),curative effect the total effective rates were 90.14% (92.08%) and 72.06% (72.73%).The total effective rate of experimental group was higher than that of the control group,the difference was statistically significant.In this experiment,three cases of clinical adverse events were reported,which were not related to the experimental drug.It also not belongs to adverse drug reactions.Conclusion Rongxin Pill in the treatment of viral myocarditis in children (deficiency of both qi and yin and heart meridian stasis syndrome) is more effective than coenzyme Q 10 capsule,and there was no indication of higher risk of clinical application.
7.Serum nutritional markers are predictors of early mortality in hospital-acquired acute kidney injury
Shuai MA ; Qionghong XIE ; Huaizhou YOU ; Ying ZHOU ; Jing QIAN ; Dingwei KUANG ; Junfeng LIU ; Qiliu HE ; Chuanming HAO ; Yong GU ; Shanyan LIN ; Feng DING
Chinese Journal of Nephrology 2012;28(2):89-94
Objective To evaluate the role of nutritional parameters in prognosis,especially in the early and late mortality of hospital-acquired acute kidney injury (AKI) patients.Methods This study was a prospective cohort study conducted in a hospital comprising 1500 beds in Shanghai, China. One hundred ninety-four patients with hospital-acquired AKI, as determined using the RIFLE staging criteria,were enrolled as subjects after obtaining informed consent.Patients with AKI caused by postrenal obstruction,glomerulonephritis,interstitial nephritis or vasculitis were excluded.Nutritional evaluation,including subjective global assessment (SGA),anthropometric and laboratory examination,was conducted. Other laboratory measurements and clinical data were recorded.The primary outcome was early mortality (≤ 7 days) and late mortality (8-28 days) after enrolling into the study. Results AKI patients at enrollment were characterized by a high prevalence of malnutrition as determined by SGA, anthropometric and laboratory examination.Univariate analysis showed that the SGA,the serum levels of prealbumin,cholesterol and total lymphatic cells, and the Maastricht index were significantly different among early mortality,late mortality and survival groups.The serum prealbumin and cholesterol levels in the early death group were significantly lower than those in the survival and late death groups (P<0.05).Multivariate analysis revealed that SGA,albumin,prealbumin and cholesterol remained independently and significantly associated with early mortality after adjusting for age,sex,dialysis,ventilation,hemoglobin,platelets,bilirubin,and Glasgow coma score.The areas under the receiver operating characteristic curve to predict early mortality for albumin,prealbumin and cholesterol were 0.591,0.736 and 0.603,respectively,with that of prealbumin significantly higher than others (P<0.05). Conclusion Low levels of serum prealbumin,albumin and cholesterol at enrollment are independtly associated with increased early mortality in hospital-acquired AKI patients.
8.Subjective global assessment predicts the prognosis of patients with hospital-acquired acute kidney injury
Ying ZHOU ; Huifang GU ; Qionghong XIE ; Zhongye XU ; Shuai MA ; Huaizhou YOU ; Dingwei KUANG ; Yong GU ; Chuanming HAO ; Shantan LIN ; Feng DING
Chinese Journal of Nephrology 2011;27(8):567-571
Objective To elucidate the malnutrition in patients with hospital-acquired acute kidney injury(AKI), and to examine the association betweensubjective global assessment (SGA) and prognosis.Methods Adult patients with hospital-acquired AKI were prospectively enrolled in this cohort study.Nutritional evaluations, including SGA, anthropometric and serum nutritional markers were conducted at enrollment.Overall survival at 90 days among different SGA scores was analyzed using Kaplan-Meier methods, and differences were tested using the log-rank test.The Cox model was used to analyze the relationship between SGA scores and all-cause mortality after adjusting for confounders.Results A total of 170 patients were enrolled.The prevalence of moderate malnutrition(SGA B) and severe malnutrition(SGA C) was 51.8% and 22.9% respectively, while patients with normal nutrition(SGA A) accounted for 25.3%.After 90 days follow-up, all-cause mortality was 9.8% in SGA A group, 34.9% in SGA B group and 56.8%inSGACgrouprespectively. Afteradjustingforage,sex,dialysis,ventilation, hemoglobin, platelets and bilirubin, the hazard ratio(HR) of 90 days all-cause mortality was 4.0(95% CI 1.42-11.22, P=0.008) in malnutrition group (SGA B group and SGA C group) compared with SGA A group.The Kaplan-Meier curve also revealed that the worse the SGA score was, the lower the cumulative survival became (P<0.01).Conclusion SGA score is an independent risk factor for all-cause mortality within 90 days in patients with hospital-acquired acute kidney injury.
9.Assessment of left ventricular systolic function with magnetic resonance imaging: comparison with that of echocardiography.
Lingyi WEN ; Heng SHAO ; Yan KUANG ; Xi LIU ; Shuai ZHANG ; Yingkun GUO ; Zhigang YANG
Journal of Biomedical Engineering 2013;30(4):748-751
This study is designed to test the agreement in measuring left ventricular systolic function between transthoracic two-dimensional echocardiography (2DTTE) and "gold standard" of non-invasive cardiac imaging, magnetic resonance imaging (CMRI) and their impacts on the classification of patients according to the left ventricular ejection fraction (EF). 32 patients who were suspected with heart disease were evaluated by CMRI and 2DTTE examinations. End diastolic volume (EDV), end systolic volume (ESV), EF and left ventricular function category were then calculated and compared. There was no significant difference (P=0.504) for EDV, while ESV of CMRI was significantly higher than that of 2DTTE (P=0.049), and EF of CMRI was significantly lower than that of 2DTTE (P= 0.018). There was no significant difference (P=0.077) in left ventricular functional category. Bland-Altman analysis of LV volumetric data and EF measurements showed a good agreement between two methods. The 2DTTE over-estimated I (n=5) or II (n=1) degrees of functional classification when compared with the CMRI. Both CMRI and 2DTTE are of great clinical value in evaluating left ventricular systolic function, while CMR may be more beneficial to patients with abnormal LV functions.
Adolescent
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Adult
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Aged
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Echocardiography
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Female
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Heart Diseases
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physiopathology
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Humans
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Retrospective Studies
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Systole
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physiology
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Ventricular Function, Left
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physiology
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Young Adult
10.Single Center Analysis of Bloodstream Infection Clinical Characteristics and Prognosis in Patients with Hematological Malignancies in the Tropics.
Long-Can CHENG ; Ting YANG ; Hui-Hui KUANG ; Shuai YU ; Li-Xun GUAN ; Zhen-Yang GU ; Yuan-Yuan XU ; Wen-Shuai ZHENG ; Lu WANG ; Ya-Lei HU ; Xiao-Ning GAO ; Quan-Shun WANG
Journal of Experimental Hematology 2021;29(1):265-271
OBJECTIVE:
To analyze the characteristics, prognosis and risk factors of bloodstream infection in patients with hematological malignancies in the tropics, so as to provide evidence for the prevention and treatment of bloodstream infection.
METHODS:
The clinical features, blood culture results and prognosis of patients with bloodstream infection in patients with hematological malignancies admitted to Hainan Hospital of PLA General Hospital were retrospectively studied.
RESULTS:
The most common primary infection site of the 81 patients with hematological malignancies was lung (46.91%), followed by PICC (11.11%). The detection rate of Gram-positive bacteria and Gram-negative bacteria in the blood culture was 60.98% and 30.02%, respectively. Coagulase-negative staphylococci was the most common Gram-positive bacteria resulting in bloodstream infection in our study. Of the Gram-negatives, Klebsiella pneumoniae (34.38%) was predominant, followed by Escherichia coli (18.75%) and Pseudomonas aeruginosa (18.75%). Gram-positive bacteria was highly sensitive (100%) to vancomycin, linezolid and tigecycline. Study showed that Gram-negative bacteria had low sensitive to quinolones, in particular, the resistance rate of Escherichia coli to quinolones was as high as 83.33%. In terms of overall survival (OS), the 30-days OS of patients with Gram-negative and Gram-positive septicemia was 77.42% and 92.00%, respectively. There was no statistically significant difference between the two groups. Multivariate analysis revealed that septic shock (P=0.001, RR=269.27) was an independent risk factor for 30-day mortality, and remission status (P=0.027, RR=0.114) was an independent predictor of a favourable outcome of bloodstream infection in patients with hematological malignancies.
CONCLUSION
Gram-positive bacteria are the main pathogens causing bloodstream infections in patients with hematological malignancies in the tropics. Improving the care of PICC is an important measure to reduce the incidence of bloodstream infection in patients with hematological malignancies in the tropics. A correct treatment relieving disease and effective prevention and treatment of septic shock can reduce mortality of patients with bloodstream infection in patients with hematological malignancies in the tropics.
Anti-Bacterial Agents/therapeutic use*
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Bacteremia/drug therapy*
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Drug Resistance, Bacterial
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Gram-Negative Bacteria
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Hematologic Neoplasms/drug therapy*
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Humans
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Microbial Sensitivity Tests
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Prognosis
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Retrospective Studies
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Sepsis