Colorectal Neoplasms ; diagnosis ; prevention & control ; Humans ; Translational Medical Research

Objective This study is to conduct an overall assessment of social function of elderly pa-tients with urinary incontinence (UI) and the factors that affect the social function exactly. Thus, some nurs-ing intervention can be put forward for the patients. Methods The investigation was carried out with inter-national consultation on incontinence questionnaire short form (ICI-Q-SF), incontinence quality-of-life scale (I-QOL) and social disability screening schedule (SDSS). Results The mean score of SDSS of patients was 4.0, this score was between patients with neurosis and patients with mental illness. The number of elderly pa-tients with UI investigated in this research who had social disability was 90. The incidence of social disability was 81.82%. Age and UI were the main factors affecting the social function of elderly patients with UI. There was significant correlation between social function and quality of life, the more serious of social disability, the poor of life quality. Conclusions Significant social disability exists in the investigated elderly patients with urinary incontinence. Some effective nursing interventions must be taken to improve the situation and increase their survival quality.

Objective To explore the prognostic factors of osteosarcoma.Methods Clinical data of 32 cases with osteosarcoma were retrospectively reviewed.Sex,age,course of disease,serum level of alkaline phosphatase (AKP),tumor size,tumor site,Enneking surgical stage,surgical method and distant metastasis were statistically analyzed.Results All the patients were followed up,and 12 patients died with a median survival of 6-52 (40.28 ± 5.58) months.Overall survival rate of 3 years was 62.5％ (20/32).Univariate analysis revealed that the prognosts of osteosarcoma was significantly related to tumor site,Enneking surgical stage,surgical method and distant metastasis.Multivariate analysis suggested that Enneking surgical stage,surgical method and distant metastasis were independent prognostic factors.Conclusions Enneking surgical stage,surgical method and distant metastasis are independent prognostic factors.Early diagnosis and the radical resection of tumor can improve the prognosis.

Objective: To simultaneously detect five components (phillyrin, chlorogenic acid, chlorpheniramine maleate, vitamin C and acetaminophen) in compound paracetamol vitamin C Yinqiao tablets.Methods: Using a Waters Xselect C18 column(250 mm×4.6 mm, 5 μm), the mobile phase consisted of acetonitril-0.1 mol·L-1 NaH2PO4(pH 3.0) with gradient elution at a flow rate of 1.0 ml·min-1.The detection wavelength was 230 nm and the column temperature was 35℃.Results: The linear range of vitamin C, acetaminophen, chlorogenic acid, chlorphenamine maleate and phillyrin was 0.500-200.200, 0.499-199.600, 0.501-200.100, 0.502-200.900 and 0.488-195.400 μg·ml-1(r＞0.999), respectively.The average recovery was 99.3%(RSD=1.5%), 97.8%(RSD=1.7%), 98.5%(RSD=1.1%), 97.1%(RSD=1.7%)and 99.8%(RSD=1.2%)(n=9), respectively.Conclusion: The simple and sensitive method can be applied in the quality control of compound paracetamol vitamin C Yinqiao tablets.

Convulsive status epilepticus (CSE) is an acute,life-threatening and neurologic emergency in children.The prognosis and the incidence of recurrent CSE depend upon the underlying etiology.It is very important to find related etiology and seek solution.The underlying etiology,classification and the diagnostic evaluation of the children with CSE will be outlined in this article.

In the last few years, Many medical colleges have been joined with synthetic universities because of creat-ing the international and well-known and high level universities. In the article the author expounds the exploitation'sadvantage of synthetic university respectively from the foundational mode, the humanities and agency science, the cal-culator technique and the knowledge diversification. He also discusses the problems arising from the united universityand the correlative plan to the effect of the problems from the contradiction of resources` division,the managing mode ofthe medical education, the phenomena of "Teaching is heavier than Researching" and the popularization of highereducation, hoping to draw lessons from the advanced experience abroad extensively to enhance and perfect the newmode of our higher medical education.[

To adapt to the variety of environment,the teaching of clinical practice must face some innovations and reformations in the contents and methods.The article discusses the specialties and applications of the several main resources,such as clinical teachers(the resource of manpower)?the training center of clinical skills(the resource of methods) ?the SP(the resource of carriers),then,provides some useful information for the teaching innovations in clinical practice.

Objective To evaluate the safety of epidural resiting and the incidence of postdural puncture headache following accidental dural puncture. HZ Methods Among 63 patients of ASA I-II undergoing lower abdominal or lower extremity surgery, forty-two with postdural puncture who had received epidural resiting were randomly assigned to patient controlled epidural analgesia (PCEA) ( n =21) or control treatment ( n =21). The remaining 21 patients who had successful epidural insertion received the routine PCEA. All patients after operation received 48-hours monitoring of BP, HR, RR and SpO_2. The analgesic effect of each treatment and the occurrence of headache were also assessed. Results All operations were uneventful under epidural anesthesia. A satisfactory level of analgesia was observed in patients who received PCEA. There was no statistically significant difference in pain control between patients who had had epidural resiting and who received PCEA and those who received routine PCEA. No respiratory inhibition was observed. The occurrence of headache in the epidural resiting group was 19% (4/21), compared to 57% (12/21) in the control group ( P

Objective To summarize the clinical treatment experiences of chronicity cardiac insufficiency with the diluting-style hyponatremia.Methods Treat 112 patients who were suffering from chronicity cardiac insufficiency with the diluting-style hyponatremia with operating water ingestion limit,blood vessel expansion,myocardial contractility strengthening besides given 3% sodium chloride and furosemide treatment.It was compared the former heart function classification,effective,hyponatremia level with after given treatment. Results One hurdred and tweleve patients after given treatment,90 patients′ heart function were level Ⅱ,12 patients′ heart function were level Ⅲ,The difference had a statistics meaning(P

Objective To explore dental phobia in children 's oral treatment sevoflurane inhalation anesthesia clinical results.Methods 100 cases of dental phobia children in our hospital between January 2012 to January 2014 were observed, which were divided to the school -age group and preschool group , 50 patients, respectively.They were all treated with heptafluorobutyric alkyl inhalation anesthesia , and the anesthesia effects were compared .Results The adverse effects, oxygen saturation and mean arterial blood pressure changes and induction of anesthesia in chil -dren awake have statistically significant difference (p <0.05).Conclusion This study suggest that sevoflurane in -halation anesthesia is an effective dental phobia children 's oral therapy, and has a high application value .