ObjectiveTo observe the effect of early rehabilitation on motor function and prognosis of the patients with spinal cord injury (SCI).MethodsAccording to started date of rehabilitation, 60 SCI patients were divided into the early rehabilitation group (within two weeks after operation) and control group (three months after operation) with 30 cases in each group. The motor function and activities of daily living (ADL) of all patients were evaluated before and 3 months after treatment, and the incidence rates of complications of two groups were compared.ResultsAfter 3 months treatment, the incidence rates of complications often occurred after SCI such as pulmonary diseases, urinary infection, osteoporosis and adductor, extensor spasticity in the lower limbs etc. were lower than those in the control group. There was a significant difference between two groups. The motor function and ADL of the patients in the early rehabilitation group were better than those of patients in the control group ( P<0.05～0.01).ConclusionEarly rehabilitation after SCI can significantly decrease the incidence rate of complications and improve patient's motor function and ADL.

ObjectiveTo observe the effect of early rehabilitation on motor function and prognosis of the patients with spinal cord injury (SCI).MethodsAccording to started date of rehabilitation, 60 SCI patients were divided into the early rehabilitation group (within two weeks after operation) and control group (three months after operation) with 30 cases in each group. The motor function and activities of daily living (ADL) of all patients were evaluated before and 3 months after treatment, and the incidence rates of complications of two groups were compared.ResultsAfter 3 months treatment, the incidence rates of complications often occurred after SCI such as pulmonary diseases, urinary infection, osteoporosis and adductor, extensor spasticity in the lower limbs etc. were lower than those in the control group. There was a significant difference between two groups. The motor function and ADL of the patients in the early rehabilitation group were better than those of patients in the control group ( P<0.05～0.01).ConclusionEarly rehabilitation after SCI can significantly decrease the incidence rate of complications and improve patient's motor function and ADL.

It is generally accepted that locomotion in mammals, including humans, is based on the activity of neuronal circuits within the spinal cord (the central pattern generator, CPG). Recent studies indicate a plastic behavior of the spinal neuronal circuits following a spinal cord injuries (SCI). Studies have shown that body weight support treadmill training (BWSTT) is effective in restoring locomotor function in cats with a complete spinal lesion. It has become possible to regain some locomotor activity in patients with spinal cord injury through an intense training on BWSTT, as in cat. So, it is a staired problem how to take advantage of the plasticity of spinal locomotor pattern generator and design the gait training program for SCI patients.

Objective To clone and express inhA gene from mycobacterium tuberculosis , and purify the inhA protein. Methods Recombinant plasmid pET 24b/inhA was constructed and transferred into Escherichia coli . After restriction enzyme analysis and sequencing, the host bacteria were induced by IPTG and the product was identified by SDS PAGE. Furthermore, the overexpressed inhA protein was purified by Nit NTA Superflow system. Results The inhA gene was overexpressed in E. coli, the production was corresponding to 30 percent of total cell protein. Using Nit NTA Superflow,we can get more than 99% purified protein. Conclusions The cloning, expression and purification of inhA gene are successful.

Objective To evaluate the clinical significance of multi - tumor markers combined detection in patients with idiopathic pulmonary fibrosis. Methods The serum levels of alpha fetoprotein (AFP) , careinoembryonic antigen (CEA), cancer antigen 125 (CA125) ,carbohydrate antigen 153(CA153) .carbohydrate antigen 199(CA199) were determined in 27 patients of idiopathic pulmonary fibrosis and 24 healthy volunteers. At the same time,the clinical indicators, such as lung function,were also measured in 27 patients. Results In comparison to control group, the serum levels of AFP, CEA,CA125 , CA153, CA199 were obviously lower than those in control group(P0.05). Conclusion Tumor markers,CA199 in particular,reflect the severity and poor prognosis of IPF patients and may also indicate the progression of pulmonary fibrosis, but they have nothing to do with disease activity.

ObjectiveTo expose the effects of toes movement treating on the improvement of motor function of the patient s' affected lower limb.Methods36 patients with hemiplegia were divided into twe groups,22 patients for treating group in which toes treatment was applied, and 14 patients for comparative group in which no toes treatment was applied.After two months treatment, the effect was judged using Japanese Motor Function Test.Results22 patients in the treating group had gotten level 8 or higher (100%), while 7 patients in the comparative group had gotten that(50%).ConclusionToes movement treating is important in the recovery of functional movement of the hemiplegia patients.

ObjectiveStudy the efficacy of physiotherapy (PT) in the rehabilitation of the patients with Guillain-Barre syndrome. Method15 patients with Guillain-Barre syndrome were divided into 2 groups,exercise group(8 cases) and control group(7 cases),a retrospective study is made.ResultAs compared with control group, there is a significant improvent in muscle strenth and ADL in exercise group (P<0.01).ConclusionPT can effectively diminish the degree of disability of the patients with Guillain-Barre syndrome, shorten rehabilitation time ,and restore independence of self-care.

Group A,the differences among the three groups were statistically significant(P0.05). TCR,CCR,DAP,OD,BRC in Groups B and C showed trends of increasing,the differences in terms of the contents of BMP-RⅠamong the 3 phases were statistically significant(P0.05);the ER in Group B and C showed a trend of decreasing,thee difference between 4- and 8-week and 4- and 12-week were signifieantly dif- ferent(P0.05).Conclusion After application of glucocorticoid for a short term,pathological changes maintained and showed trends of inereasing in early stage.HBO can reverse these changes.The outcome of 3-course HBO therapy is better than that of 1-course therapy.

ObjectiveTo explore the relations between the alkaline phosphatase(ALP) and the type of cerebral palsy. MethodsThe ALP level of 40 children with different types of cerebral palsy were examined with the Olympus AU-600 apparatus. ResultsThe ALP value of the children with spastic cerebral palsy is normal. The ALP value of the children with athetoid cerebral palsy is higher than spastic cerebral palsy(P<0.001).Conclusions The ALP value can help us to identify the type of cerebral palsy.

Afferent Pathways ; Animals ; Female ; Nerve Block ; Olfactory Bulb ; metabolism ; Parvalbumins ; metabolism ; Rats ; Rats, Wistar