1.Determination of the Content of Astragaloside Ⅳ in Qi Zao Granules By HPLC-ELSD
Huaqing LIN ; Hong DENG ; Shu ZHANG
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(02):-
Objective To determine the content of astragaloside Ⅳin Qi Zao Granules.Methods Equipped with the evaporative light scattering detector (ELSD), a RP-HPLC method was established. The chromatographic column was C18 and the column temperature was at 30 ℃.The drift tube temperature was at 40 ℃and the evaporative gas was nitrogen with pressure of 3.5 bar.The mobile phase was acetonitrile-water(30∶70) and the flow rate was 1mL/min. Results This method showed a good linear relationship in the range of 2.51~50.2 ?g astragaloside Ⅳ. The average recovery was 98.13 %with RSD being 1.28 %. Conclusion The method is sensitive and accurate and can be used for the quality control of Qi Zao Granules.
4.Noninvasive gastric motility measurement and evaluation by bioimpedance
Chaoshi REN ; Zhangyong LI ; Wei WANG ; Shu ZHAO ; Juan DENG
Chinese Journal of Tissue Engineering Research 2010;14(9):1653-1657
BACKGROUND:Bioimpedance method can be used to extract physiology and pathology information relative to the gastricmotility states,to investigate the courses of contraction,peristalsis,transmission and emptying of the stomach,to measure andevaluate gastric motility function.However,early studies mainly focused on the emptying of the stomach,and few studies onevaluation of gastric motility by extracting gastric motility information.OBJECTIVE:To understand the gastric motility from electricity-mechanism composite concept and to establish a noninvasive,convenience measurement method of gastric motility impedance.METHODS:Based on the characters of gastric motility impedance signal,a measurement method of impedance gastric motility isintroduced.Some foundation experiments about the gastric emptying measurement,the gastric motility compare between fastingand repast,the gastric motility comparison of healthy volunteers during different periods and some medicine effects on gastricmotility have carried out.The gastric motility measurement of the patients with functional dyspepsia and gastric motility evaluationfor the patients with erosive gastritis had been reported.RESULTS AND CONCLUSION:Using electrical bioimpedance method,according to the electrical property of the stomach tissueor the food in stomach and the change rules of the property,the physiology and pathology information relative to the gastricmotility states can be extracted,the courses of contraction,peristalsis,transmission and emptying of the stomach can beinvestigated and noninvasive measure and evaluation of gastric motility function can be realized.
6.One-stage posterior and anterior surgical management of thoracolumbar spinal tuberculosis
Zhongyuan DENG ; Shanhu HUANG ; Zhenhua JIANG ; Chunhua LI ; Yong SHU
Clinical Medicine of China 2009;25(5):523-525
Objective To explore the therapeutic efficacy of posterior internal fixation and anterior debride-ment with autogenous bone grafts at one stage on tuberculosis of thoracic or lumbar spine . Methods 16 cases of thoracic or lumbar spinal tuberculosis patients were treated with combined anterior (radical debridement and bone autograft) and posterior (instrumentation) surgeries in one stage between September 2003 and September 2007. The degree of the kyphosis (Cobb angle) was measured and the interbody fusion was observed preoperatively and postop-eratively. The ASIA grading system was used to assess the neurological status. Results All patients were followed up for 10 months to 36 months,on average of 12 months. All patients showed sucessful interbedy fusion,but Cobb angle was not progressed. No recurrence or wound infection was found. 6 cases all got nerve function recovery. Conclusion Thoracic or lumbar tuberculosis treated with this surgical technique can achieve stable internal fixation and a high satisfactory rate with restoring the spinal stability, arresting the disease early, providing early fusion, correcting the ky-pbosis particularly.
7.The relationship of impulsive personality and parental rearing patterns in junior middle school students
Erli SHU ; Yunlong DENG ; Hong YUAN ; Bingqing GUAN
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(6):552-554
Objective To study the development of impulsive personality in junior middle school students of Changsha, and to explore its relationship with parental rearing patterns. Methods 409 students were investigated by Egna Minnenav Barndoms Uppfostran ( EMBU ) and Barratt Impulsivity Scale ( BIS-11 ). Results Male and female had significant difference in attention impulsiveness scores((20.56 ±3.60) vs ( 19.63 ±3.07) , P< 0.01). Grade 7 and Grade 9 had significant difference in attention and motor impulsiveness scores((20. 58 ± 3.47)vs (19.63 ±3.46) , P<0.05;(20. 31 ±4.37)vs (21.75 ±4.00) , P< 0.01). Parental warmth and understanding was negatively correlated with attention , non-planning and total scores of impulsiveness ( r= - 0. 23 ~ -0.33, P<0.01). Parental refusal and rejection was positively correlated with total and factors of BIS-11 ( r = 0. 23 ~0. 33 , P<0. 01 ) . Parental punishment and rigor was positively correlated with motor and total scores of im-pulsiveness( r = 0.22 -0.26, P<0.01). Parental over-interference and overprotection was positively correlated with motor impulsiveness ( r = 0. 23 ~0. 34, P<0. 01). Mother's punishment and rigor was positively correlated with attention impulsiveness( r = 0.22, P<0. 01 ). Father' s overprotection and Mother' s over-interference and overprotection was positively correlated with total scores of impulsiveness ( r = 0. 23 ;0. 25 , P < 0. 01) . Stepwise regression analysis revealed that factors and total of BIS-11 explained by patterns rearing were 12% ,14% ,15% and 19% . Conclusion Rearing patterns can severely impact the development of impulsive personality. Impulsive personality is positively predicted by parental rearing patterns.
8.The Practice and Methods of Physician-patient Shared Decision
Shifeng LOU ; Lin CHEN ; Shu CHEN ; Jianchuan DENG
Chinese Journal of Medical Education Research 2003;0(03):-
Probing into the methods and techniques of physician-patient communication is important to clinic medicine and medical education. Physician- patient shared decision is one of important aspects of physician-patient communication, 80 patients with hematologic malignancies were reviewed for classification of models of medical decision making, and the methods and techniques of physician-patient shared decision were also discussed .
9.Post-weaning social isolation regulates social exposure-induced vasopressin release in the paraventricular nucleus
Yu Wang ; Shu-min Deng ; Qun-ying Fu ; Xu Liu
Neurology Asia 2013;18(3):293-301
Background & Objective: Early life stresses, such as social isolation, have lasting effects on the
development of emotion and behavior, in which vasopressin plays important roles. This study aimed
to assess the possible association of central release of vasopressin with social isolation. Methods:
The social isolation model was performed in male mice who endured 6-week social isolation after
weaning. Vasopressin expression in the paraventricular nucleus of hypothalamus (PVN) was measured
with immunohistochemistry. Released vasopressin from PVN was measured with radioimmunoassay.
Results: Vasopressin immunoreactive cells number decreased in the PVN, medial parvocellular division
in social isolation-reared mice, compared to the group-reared counterparts. Social isolation decreased
short social exposure-induced vasopressin release from PVN. Isolation-reared mice exhibited anxiogenic
profile and difficulty in social recognition.
Conclusions: This study provides new evidence for the important role of vasopressin in the development
of emotional and social behaviors.
10.Application of 5S Theory in Ward Drug Control
Fulan WANG ; Chunmei SHU ; Hongyong BAO ; Liling XIE ; Quanlin DENG
China Pharmacy 2005;0(24):-
OBJECTIVE:To discuss ward drug control to ensure safe.METHODS:We analyzed retrospectively the application of 5S theory in ward drug control.RESULTS & CONCLUSION:By this drug control mode,drugs were classified according to varieties,usage,frequency of use etc,drug control quality and work efficiency were enhanced,patients' needs could be satisfies and staff' s professional quality was enhanced.