1.Advances in mesenchymal stem cells combined with traditional Chinese medicine therapy for liver fibrosis.
Journal of Integrative Medicine 2014;12(3):147-155
Liver fibrosis is a primary cause of liver cirrhosis, and even hepatocarcinoma. Recently, the usage of mesenchymal stem cells (MSCs) has been investigated to improve liver fibrosis. It has been reported that the differentiation, proliferation and migration of MSCs can be regulated by traditional Chinese medicine treatment; however, the mechanisms are still unclear. In this article, the authors review the characteristics of MSCs such as multidirectional differentiation and homing, and its application in animal experiments and clinical trials. The authors also list areas that need further investigation, andlook at the future prospects of clinical application of MSCs.
2.Treatment of fresh Monteggia fractures of Bado type I and II in children by closed reduction and ulna intramedullary nail fixation.
China Journal of Orthopaedics and Traumatology 2016;29(1):64-67
OBJECTIVETo investigate the effects of closed reduction and ulna intramedullary nail fixation for the treatment of fresh Monteggia fractures of Bado type I and II in children.
METHODSTwenty-three children patients with Monteggia fracture during July 2010 to September 2013 were treated by closed reduction and ulna intramedullary nail fixaion including 18 boys and 5 girls with an average age of 9.3 years old ranging from 6 to 13 years old. Among them,15 cases were Bado type I and 8 cases were Bado type II. There were 9 cases with radial nerve injury. The operation time,the recovery of nerve injury, the fracture healing and the function of elbow were observed and recorded.
RESULTSAll patients were followed up for 6 to 24 months (12 months on average). All patients were obtained bone healing. According to Anderson standard, at the final follow-up, 20 cases got excellent result, 2 cases got good result, and one case got fair result.
CONCLUSIONTreatment of the fresh Monteggia fractures in children by closed reduction and ulna intramedullary nail fixation has advantages of simple operation, less trauma and good results.
Adolescent ; Child ; Female ; Fracture Fixation, Intramedullary ; methods ; Fracture Healing ; Humans ; Male ; Monteggia's Fracture ; surgery ; Ulna ; surgery
4.Study of indicators and methods of developmental course evaluation based on investigation of teachers and students
Wei DONG ; Lin WANG ; Jing SHU
Chinese Journal of Medical Education Research 2017;16(7):649-652
Considering a variety of theories such like Dunkin's, Centra's and Kolitch's, a set of 13 indicators are designed to evaluate effect of courses taken in high education of China currently, compro-mised by chief aspects of course designing, practicing, and effect. Three courses including medical nursing, humanistic cultivation and communication skills in nursing and fundamentals of nursing in a nursing de-partment are chosen to be objects of questionnaire survey about the above indicators. The results show that there are significant differences in curriculum effectiveness between different courses. The scores are 2.81, 2.80 and 2.60 respectively, and teachers and students have different evaluation on the same indicators of the same curriculum,which provides a reference for teachers, colleges and universities and teaching management departments to promote the improvement of teaching quality.
5.The Application of Meta- analysis to the Treatment of Lower Respiratory Tract Infection with Ceftriaxone
Zhigao HE ; Dong ZHOU ; Lixin SHU
China Pharmacy 2001;12(5):280-282
OBJECTIVE: Evaluating clinical efficacy of ceftriaxone in the treatment of lower respiratory tract infections METHODS: Applying meta- analysis to evaluation of clinical efficacy of ceftriaxone, cefotaxime and cefuroxime in the treatment of lower respiratory tract infections RESULTS & CONCLUSION: Ceftriaxone is worthy of popularization and application in clinical practice because of its better efficacy and lower cost
6.Clinicopathological observation on 2 cases of nasal-type NK/T-cell lymphoma in the esophagus.
Shu ZHANG ; Hai WANG ; Dong-ni LENG
Chinese Journal of Oncology 2008;30(10):767-769
Antineoplastic Combined Chemotherapy Protocols
;
therapeutic use
;
CD56 Antigen
;
metabolism
;
Cyclophosphamide
;
therapeutic use
;
Doxorubicin
;
therapeutic use
;
Esophageal Neoplasms
;
drug therapy
;
metabolism
;
pathology
;
radiotherapy
;
Follow-Up Studies
;
Humans
;
Leukocyte Common Antigens
;
metabolism
;
Lymphoma, Extranodal NK-T-Cell
;
drug therapy
;
metabolism
;
pathology
;
radiotherapy
;
Male
;
Middle Aged
;
Poly(A)-Binding Proteins
;
metabolism
;
Prednisone
;
therapeutic use
;
T-Cell Intracellular Antigen-1
;
Treatment Outcome
;
Vincristine
;
therapeutic use
7.Lynch syndrome-related endometrial carcinoma.
Chinese Journal of Pathology 2012;41(7):494-497
Adaptor Proteins, Signal Transducing
;
metabolism
;
Adenocarcinoma, Clear Cell
;
genetics
;
metabolism
;
pathology
;
surgery
;
Adenosine Triphosphatases
;
metabolism
;
Age Factors
;
Carcinoma, Endometrioid
;
genetics
;
metabolism
;
pathology
;
surgery
;
Colorectal Neoplasms, Hereditary Nonpolyposis
;
genetics
;
metabolism
;
pathology
;
surgery
;
Cystadenocarcinoma, Serous
;
genetics
;
metabolism
;
pathology
;
surgery
;
DNA Mismatch Repair
;
DNA Repair Enzymes
;
metabolism
;
DNA-Binding Proteins
;
metabolism
;
Endometrial Neoplasms
;
genetics
;
metabolism
;
pathology
;
surgery
;
Female
;
Humans
;
Mismatch Repair Endonuclease PMS2
;
MutL Protein Homolog 1
;
MutS Homolog 2 Protein
;
metabolism
;
Neoplasms, Multiple Primary
;
genetics
;
metabolism
;
pathology
;
surgery
;
Nuclear Proteins
;
metabolism
8.An Ethical Discussion on the Case of Intra-vital Organ Donations between Relatives
Yi LEI ; Shu DONG ; Hongzhu ZHOU
Chinese Medical Ethics 1994;0(06):-
This study based on an ethical review of the kidney donation from a young man to his elder relative.We discuss the problems existing in present field of intra-vital organ transplantations,as well as its risk and the ethics review mode.It is recommended that ethics review is performed as a complete procedure,which should not only present in certain format,but also emphasize weighing the advantages and disadvantages of both patients and donors;intra-vital organ transplantations between relatives should also follow the principle of "no compensation and non-commercialization";hospitals should give out the judgment under sufficient considerations of both patients' and donors' benefits within the scope of laws,as well as taking into account of other factors such as prospective outcome of the operations,rather than barely basing on the risk probabilities.
9.The Application of Meta-analysis to the Treatment of Lower Respiratory Tract Infection with Ceftriaxone
Zhigao HE ; Dong ZHOU ; Lixin SHU
China Pharmacy 1991;0(05):-
OBJECTIVE:Evaluating clinical efficacy of ceftriaxone in the treatment of lower respiratory tract infections METHODS:Applying meta-analysis to evaluation of clinical efficacy of ceftriaxone,cefotaxime and cefuroxime in the treatment of lower respiratory tract infections RESULTS & CONCLUSION:Ceftriaxone is worthy of popularization and application in clinical practice because of its better efficacy and lower cost