Humans ; Periodontal Diseases ; complications ; microbiology ; Periodontium ; microbiology ; Systemic Inflammatory Response Syndrome ; microbiology

Equipment Design ; Humans ; Pacemaker, Artificial

Colorectal Neoplasms ; diagnosis ; prevention & control ; Humans ; Translational Medical Research

Central nervous system demyelination in children include acute disseminated encephalomyelitis (ADEM),multiple sclerosis (MS),optic neuritis(ON),transverse myelitis(TM),neuromyelitis optica(NMO).Most of these conditions are thought to be caused by immune -mediated demyelination triggered by an infectious agent in a ge-netically susceptible host.There are certain differences,including clinical features and imaging features,for these condi-tions.With the possible exception of the NMO -IgG autoantibody found in NMO,there are no disease -specific biomar-kers for these conditions,making it difficult to distinguish among them at the time of the initial presentation.However, certain clinical features,laboratory results,and imaging findings can usually lead to the correct diagnosis.MS is to a large extent still a diagnosis of exclusion,and therefore requires intense investigation for other conditions that might present in a similar manner.

Objective:To evaluate the long-term safety of living kidney donors after nephrectomy.Methods:Twenty-six living donors of kidney were followed up for 2-8 years,with a mean of(4.27?2.11)years.The serum creatinine,blood pressure, proteinuria and psychological stress were observed in the donors during follow-up.Results..The serum creatinine had a significant increase after nephrectomy(P

Objective: To study the effect and mechanism of glutamine(Gln) on the intestinal barrier function in rats. Methods: Forty-five Sprague-Dawley rats were randomly divided into three groups(groupⅠ,groupⅡand groupⅢ) of fifteen animals each:.Rats of groupⅠ,groupⅡwere fed on normal diet and group Ⅲ was fed on 3% Gln-supplemented diet.The stress model was established in rats of groupⅡand Ⅲ.3 weeks later,the D-lactate,Gln levels in plasma and the contents of corticotropic releasing hormone(CRH),neurotensin(NT) in brain were measured.The morphology of small intestinal protein,DNA contents and its mucosa were observed. Results: Compared with control group,stress increased D-lactate level in plasma and reduced plasma glutamine level and the content of protein and DNA in small intestinal mucosa respectively.The small intestine demonstrated evident pathological characteristics under stress.Compared with stress group,D-lactate level in plasma was reduced and DNA content in small intestinal was increased in group Ⅲ.The CRH content in brain tissue was reduced and NT content in brain tissues was increased after Gln-supplemented.The pathological picture of small intestinal mucosa under stress was ameliorated after Gln-supplemented.Conclusion: The intestinal barrier function of rats may be protected after Gln-supplementation.Gln-derived neurotransmitters could alleviate the stressful damage of intestinal mucosa.

Intracranial pressure monitoring is a mainstay in the management of children with severe traumatic brain injury.The research issues on the intracranial pressure monitoring have become important for neurocritical care.This paper has reviewed the significance of intracranial pressure monitoring in children with severe traumatic brain injury.

BACKGROUND:There is no unified conclusion on the efficacy of immediate implantation and restoration. Some studies have shown that the success rate and aesthetic effect of immediate implantation are better than those of delayed implantation. However, in other studies, the immediate implantation has no difference from the delayed implantation, and it also has safety hazards. OBJECTIVE:To observe the clinical efficacy and safety of BLB implant for immediate implantation and delayed implantation. METHODS:Eighty patients undergoing denture implantation and restoration, 35 males and 45 females, aged 20-52 years were equaly divided into research group treated with immediate implantation of BLB implant and control group treated with delayed implantation. Crown restoration was completed at 3 months after implantation. Then, the patients were folowed up for 6 months to observe the implant stability, implantation efficacy and adverse effects. RESULTS AND CONCLUSION:There was no intra-group or intergroup difference in the implant stability quotients of two groups at 1, 3, 6 months after restoration (P> 0.05). The total effective rate was 95% in the research group and 90% in the control group, and there was no significant difference between the two groups (P > 0.05). In the research group, there was one case of gingivitis and one case of lower lip numbness; in the control group, there were two cases of wound infection and one case of lower lip numbness, but there was no difference in the incidence of complications between the two groups (P > 0.05). These findings indicate that BLB implant has good efficacy and safety both in immediate implantation and delayed implantation.

Objective:To screen auramine O in Guci tablets. Methods:Auramine O was detected by HPLC method on a Diamon-sil-C18(250mm×4.6mm,5μm)columnwiththemobilephaseofacetonitrile-0.025mol·L-1monopotassiumphosphatebuffersolu-tion(containing 0. 2% triethylamine,adjusting pH to 3. 0 with phosphoric acid)(36∶65)at the flow rate of 0. 8 ml·min-1. The detec-tion wavelength was 432 nm and the column temperature was 35℃. Results:The LOD of auramine O was 0. 05ng. Among 45 batches of tested samples, auramine O was found in seven ones. Conclusion:The method is simple, rapid and accurate, which can guarantee the drug safety of Guci tablets.