Objective To investigate and analyze the blood uric acid level and the detection rate of hyperuricemia (HUA) and to discuss its related risk factors. Methods From January to December 2016, physical and biochemical examination were conducted to a total of 7 585 cases with health examination, which were selected by using cluster sampling method. We analyzed the detection rate in percentage and the related factors of HUA by applying Pearson test and Logistic regression. Results Detection rate of HUA in this group was 32.76%, with 32.88% males and 32.69% females. The average blood uric acid level presented (358.98±91.11) μmol/L, of which male was (368.25±91.11) μmol/L and female was (343.13±91.12) μmol/L. Positive correlation was shown between blood uric acid levels and systolic blood pressure, diastolic blood pressure, BMI, total cholesterol, triglyceride, low density lipoprotein(LDL-C)(P＜ 0.05), while negative correlation was revealed between blood uric acid levels and high density lipoprotein(HDL-C)in both males and females (P＜ 0.05). The independent risk factors of HUA were high systolic blood pressure, high triglyceride and low LDL-C, and the protective factor was high HDL-C. Conclusions Hyperuricemia is often associated with high systolic pressure, hypertriglyceridemia and low LDL-C. Attention should be paid when it comes to health interventions in people with elevated serum uric acid level.