1.The comparison between Chinese and American medical education and its inspiration
Shouqiang LI ; Yue LIU ; Xiaoping LENG
Chinese Journal of Medical Education Research 2015;(1):14-16
The medical education of China and the United States was compared by analyzing the differences about educational system, teaching mode and teaching content in this paper. Standard-ization of the Chinese medical education system, improving clinical practice, teaching students by initi-ating questions and advanced medical education technology were recommended in China. This paper will inspirit and provide experience for the innovation of Chinese medical education.
2.Low-Field-MRI in Assessing the Vessels Surrounding Pancreas Involved by Pancreatic Carcinoma
Shouqiang JIA ; Yongxiu WANG ; Qingguo LI ; Ying CHEN ; Na LI ; Huizhen SUN
Journal of Practical Radiology 2001;0(08):-
Objective To study the accuracy,clinical value and limit in assessing the vessels surrounding pancreas involved by pancneutic carcinoma with low field MRI.Methods MRI scanning was performed in 55 patients with pancreatic carcinoma.We prospectively evaluated the MRI findings of vascular involvement by pancreatic carcinoma,and compared with the surgical results.Results Of total 55 cases,50(91%)cases were correctly diagnosed on MRI .MRI carries an accuracy of 86% for prediction of resectility,and accuracy of 93% for unresectility.Conclusion Low field MRI can accurately assess the peripancreative vessels ,but it has limited value in the patients with pancreatic carinomaⅠa orⅠb.
3.Detection of acute cellular rejection in heart transplantation at the early stage using two-dimensional speckle tracking imaging and ICAM-1-targeted myocardial contrast echocardiography
Chengcheng HU ; Yingjie LIU ; Jiawei TIAN ; Shouqiang LI ; Dandan YU ; Xiaoping LENG
Chinese Journal of Ultrasonography 2017;26(4):338-343
Objective To investigate whether two-dimension speckle tracking imaging(2D-STI) and ICAM-1-targeted myocardial contrast echocardiography could detect the acute cellular rejection of heart transplantation at the early stage.Methods The abdominal heterotopic heart transplantation model was successfully established using Wistar and SD rats.Forty-eight rats were divided into allografts (ALLO) group (n =24) and isografts(ISO) group (n =24).Echocardiography,2D-STI and ICAM-1 targeted myocardial contrast echocardiography were performed at 1,3,5 day after transplantation respectively.After ultrasound imaging,transplanted hearts were harvested for Hematoxylin-eosin staining and immunofluorescence histochemistry to evaluate acute cellular rejection and ICAM-1 expression.Results There were obvious difference between ALLO group and ISO group in echocardiographic parameters at 5 days after transplantation surgery (all P <0.05).Compared with those in ISO group,global circumferential strain and strain rate (GCS,GCSr),and circumferential strain of endo-myocardium (CSendo) decreased in ALLO group at day 3 post-transplantation (all P<0.05).Compared with those in ISO group,all strain parameters in ALLO decreased significantly at postoperative day 5 (all P< 0.05).Myocardial contrast echocardiography using ICAM-1-targeted microbubbles showed that the video intensity in ALLO group was significant higher than that in ISO group at postoperative day 3 and day 5 (all P<0.05).Conclusions 2D-STI and myocardial contrast echocardiography using ICAM-1-targeted microbubbles are sensitive and useful for detecting heart transplant acute rejection at the early stage.
4.CiteSpace-based visualization analysis of traditional Chinese medicine treatment for patients after receiving percutaneous coronary intervention
Yunxiao ZHANG ; Zhenhai SUN ; Menghe ZHANG ; Shudi LI ; Wenwen LI ; Yuwei XING ; Yan LI ; Shouqiang CHEN
Journal of Interventional Radiology 2024;33(10):1064-1072
Objective By using CiteSpace-based visualization analysis to investigate the main research contents,research frontiers,author cooperation network and institutional cooperation network of traditional Chinese medicine(TCM)treatment for patients after receiving percutaneous coronary intervention(PCI)so as to provide reference for the TCM diagnosis,treatment and research of patients after receiving PCI.Methods A computerized retrieval of academic papers concerning TCM treatment of patients after receiving PCI from CNKI,VIP and Wanfang databases was conducted.The retrieved literature materials were input into NoteExpress software to make the literature screening and the data cleaning.CiteSpace software was used to analyze the key words,authors,institutions,etc.Results A total of 1 708 articles were obtained;the number of published articles in 2020 was the largest,which was up to 137 articles.The core authors accounted for 4.37%of the total number of authors who had written articles,but no core author group had been formed yet.Liaoning province of China was the region where the number of published articles was the largest,and there was no effective collaboration network between different areas.The cluster analysis yielded 25 clusters,448 key nodes and 1 266 lines.The main cluster results were coronary heart disease,acute coronary syndrome,acute myocardial infarction,restenosis,etc.The analysis of emergent words(i.e.the suddenly increased frequency of a certain key word in a certain period)yielded 24 emergent words,including syndrome differentiation of TCM,ginseng peony oral liquid,cardiac rehabilitation,etc.Conclusion The main research contents of TCM treatment for patients after PCI include syndrome differentiation of TCM,etiology and pathogenesis,clinical trials,etc.Postoperative pathological phenomena such as restenosis are the research difficulties in this field,and anxiety,dual-mind TCM,and cardiac rehabilitation are the current research hotspots.TCM has definite efficacy in promoting the recovery of cardiac function after PCI,in reducing the incidence of postoperative events such as restenosis,and in improving anxiety and depression.
5.Clinical research of differential diagnosis of circular enhanced brain lesions by 1.5TMRI
Min ZHANG ; Shouqiang JIA ; Jinling WANG ; Min WANG ; Feng LI
Chinese Journal of Neuromedicine 2014;13(12):1215-1217
Objective To evaluate the value of 1.5T MRI in differential diagnosis of circular enhanced brain lesions.Methods A total of 120 patients,admitted to our hospital from April 2009 to March 2013 and confirmed by clinical pathology,including 40 of brain metastasis,40 of astrocytoma and 40 of brain abscess,were chosen in our study; The characteristic signs of MRI findings of these patients were retrospectively analyzed.Results There were significant differences in the location,number,size,morphology,ring structure,multiple mural nodules,and smooth outside wall of the lesions between patients with brain metastasis and astrocytoma.There were significant differences in the number,size,ring structure,ring wall thickness,and smooth outside wall of the lesions,T2-weighted imaging (T2WI) low signal ring sign,hydraulic fluid level sign,lesion center diffusion weighted imaging (DWI) hyperintensity and apparent diffusion coefficient (ADC) map low signal between patients with brain metastasis and abscess.There were significant differences in the location,shape and multi locular lesions between patients with astrocytoma and abscess.The signs indicating brain metastasis included multi lesions,grade Ⅲ peripheral edema,small lesions,lesions located at the juncture of gray and white matter,with displaying percentages of 79.5%,70.3%,67.5%,48.5% and 47.9%.The signs indicating astrocytoma included multi locular lesion,lesions located at the white matter,multi mural nodule,rough outside wall and irregular in shape,with displaying percentages of 85.7%,78.0 %,77.8%,65.4 % and 51.9%.The signs indicating abscess included daughter ring sign,DWI hyperintensity and ADC map low signal,circular wall notch sign,hype-intensity rim on T2WI and fluid-fluid level,with displaying percentages of 100%,100%,100%,92.6% and 82.4%.Conclusion The 1.5T MRI can displaythe characteristic signs of brain metastases,gliomas and brain abscess,which enjoys high value in differential diagnosis.
6.Impact of prescribed adaptive statistical iterative reconstruction-V on image quality and radiation dosage of lung pure ground glass nodules: A phantom study
Ying LI ; Na'na AI ; Yingying ZHANG ; Yucun FU ; Jiong JIANG ; Dandan NIU ; Yanhui ZHAI ; Shouqiang JIA
Chinese Journal of Medical Imaging Technology 2018;34(5):775-778
Objective To investigate the impact of prescribed adaptive statistical iterative reconstruction V (Pre-ASiR-V) on imaging quality and radiation dosage of pure ground glass nodules (pGGN) in chest phantom,in order to obtain the optimal level of Pre-ASiR-V.Methods CT scanning for a chest phantom containing 4 artificial pGGNs was performed with Revolution CT,and the Pre-ASiR-V level was set as 0,20%,40%,60%,80% and 100% group,respectively.The mean noise,effective dose (ED) and the subjective scores of pGGN imaging were recorded and compared.Results The mean noise of groups (Pre-ASiR-V 0,20%,40%,60%,80% and 100%) was (17.93±2.20)HU,(17.30±3.68)HU,(18.20± 3.44)HU,(18.80±0.20)HU,(19.87±2.56)HU and (15.90±4.56)HU,respectively (F=0.568,P=0.723).ED of these groups was 7.40 mSv,5.16 mSv,3.36 mSv,1.97 mSv,0.97 mSv and 0.33 mSv,respectively.Compared with imaging of PreASiR-V 0,the reduction percentage of ED was 30.27%,54.59%,73.38%,86.89% and 95.54%,respectively.The subjective score of the image quality evaluated by the 2 observers had high agreement (Kappa=0.778,P=0.003),and all the scores were greater than 3.The subjective score of Pre-ASiR-V 80% and 100% group was slightly lower than those in other groups.Conclusion Different Pre-ASiR-V level slightly impacts the noise of high-resolution CT images of chest phantom,while reduces radiation dosage significantly.Pre-ASiR-V level of 60% is the optimal protocol.
7.Application of shear wave elastography combined with superb micro-vascular imaging in diagnosing benign and malignant thyroid masses
Huan JI ; Lei ZHANG ; Shouqiang LI ; Dandan YU ; Jiawei TIAN ; Xiaoping LENG
Chinese Journal of Ultrasonography 2018;27(2):143-146
Objective To investigate the application value of shear wave elastography (SWE) combined with superb micro-vascular imaging (SMI) in differentiating malignant and benign thyroid masses.Methods Seventy-eight patients diagnosed by ultrasound and verified with postoperative pathological analysis were enrolled.Conventional two-dimensional ultrasound was applied to observe the masses.SWE was performed to evaluate the elasticity and the Young's modulus (AveT1) value acquired.ROC curve was drawn to calculate the sensibility and specificity using the cut-off value of AveT1.SMI was applied to define Adler's grading standard according to the degree of blood supply.The sensitivity,specificity and accuracy of SWE and SWE combined with SMI in differentiating malignant and benign thyroid masses were analyzed.Results ①According to pathological analysis,there were 42 benign and 44 malignant masses;②The AveT1 value between malignant and benign groups were all significantly different (P <0.01).41.4 kPa was used as the best cut-off value of AveT1.The area under the ROC curve were 0.83 with sensitivity 86.9% and specificity 88.1%;③There were more masses with the Alder class Ⅱ-Ⅲ in malignant group than those in benign group,and the difference was statistically significant (P <0.01);④Quantified with SWE or SWE combined with SMI,the sensitivity were 86.9% and 91.3%,specificity were 88.1% and 92.8%,and accuracy were 87.5% and 94.1 %,respectively,and the difference was statistically significant (P < 0.01).Conclusions SWE combined with SMI represents an excellent application value in differentiating malignant and benign thyroid masses,which could improve the sensitivity,specificity and accuracy of the diagnosis for thyroid masses using ultrasound.
8.Research on lung function prediction methodology combining transfer learning and multimodal feature fusion
Jian MA ; Honglin ZHU ; Jian LI ; Wenhui WU ; Shouqiang JIA ; Shengdong NIE
International Journal of Biomedical Engineering 2023;46(6):506-513
Objective:To design a lung function prediction method that combines transfer learning and multimodal feature fusion, aiming to improve the accuracy of lung function prediction in patients with idiopathic pulmonary fibrosis (IPF).Methods:CT images and clinical text data were reprocessed, and an adaptive module was designed to find the most suitable lung function attenuation function for IPF patients. The feature extraction module was utilized to comprehensively extract features. The feature extraction module comprises three sub-modules, including CT feature extraction, clinical text feature extraction, and lung function feature extraction. A multimodal feature prediction network was used to comprehensively evaluate the attenuation of lung function. The pre-trained model was fine-tuned to improve the predictive performance of the model.Results:Based on the OSIC pulmonary fibrosis progression competition dataset, it is found through the adaptive module that the linear attenuation hypothesis is more in line with the trend of pulmonary function decline in patients. Different modal data prediction experiments show that the model incorporating clinical text features has better predictive ability than the model using only CT images. The model combining CT images, clinical text features, and lung function features have optimal predictive results. The lung function prediction method combining transfer learning and multimodal feature fusion has modified version of the Laplace log likelihood (LLLm) of ?6.706 5, root mean squared error (RMSE) of 184.5, and mean absolute error (MAE) of 146.2, which outperforms other methods in terms of performance. The pre-trained model has higher prediction accuracy compared to the zero base training model.Conclusions:The lung function prediction method designed by combining transfer learning and multimodal feature fusion can effectively predict the lung function status of IPF patients at different weeks, providing important support for patient health management and disease diagnosis.
9.Application of thyroglobulin measurement in fine‐needle aspiration for detecting lymph node metastasis in papillary thyroid carcinoma
Lili JI ; Shuangquan JIANG ; Shouqiang LI ; Lei ZHANG ; Dandan YU ; Huan JI ; Jiawei TIAN ; Xiaoping LENG
Chinese Journal of Ultrasonography 2019;28(4):313-317
Objective To explore the diagnostic value of thyroglobulin measurement with fine‐needle aspiration ( FNA‐Tg ) in detecting papillary thyroid carcinoma ( PTC ) metastatic lymph nodes ,and analyze the impact of different factors on the diagnostic accuracy of FNA‐Tg . Methods One hundred and fifty‐four lymph nodes from 138 patients w ho underwent total thyroidectomy and cervical lymphadenectomy were enrolled . Ultrasonography ,fine needle aspiration cytology ( FNAC) and FNA‐Tg results were acquired in all patients . T he diagnostic value of FNAC ,FNA‐Tg and the combination of the two methods were compared in suspicious PTC metastatic lymph nodes . T he influence of lymph nodes size ,lymph nodes cystic change and serum thyroglobulin antibody( TgAb) on the accuracy of FNAC and FNA‐Tg were analyzed . Results T he sensitivities of FNAC ,FNA‐Tg ,and the combination of the two methods in the diagnosis were 79 .5% , 95 .5% and 97 .7% ,respectively . T he specificities were 100% ,93 .9% and 100% ,respectively . T he size and cystic change of lymph nodes had effects on the accuracy of FNAC( P <0 .05) ,w hile they had no effect on the accuracy of FNA‐Tg ( P =0 .42 ,0 .67 ) . T he serum TgAb level had no influence on the accuracy of FNAC and FNA‐Tg ( P = 0 .88 ,0 .34 ) . Conclusions FNA‐Tg is sensitive to metastatic lymph nodes in PTC w hich not affected by the lymph nodes size ,the lymph nodes cystic change and serum TgAb level . Application of FNA‐Tg with FNAC can improve the sensitivity of diagnosis ,w hich is important in the diagnosis of PTC metastatic lymph nodes .
10.Improvement of image quality in portal vein dual-low CT venography with CE-Boost technique
Dandan NIU ; Yuqing SUN ; Nannan SUN ; Yancui BI ; Min ZHANG ; Ying LI ; Zhuangfei MA ; Shouqiang JIA
Journal of Practical Radiology 2024;40(6):990-993
Objective To explore the image quality improvement of portal vein computed tomography venography(CTV)using CE-Boost technique with low dose and low contrast media usage.Methods A total of 50 patients with suspected portal vein disorders who underwent abdominal non-contrast and biphasic contrast-enhanced CT scans using the Canon 320-row CT machine were retrospectively selected.Images of portal venous phase(PVP)were postprocessed with CE-Boost technique.The CT values of each area,standard deviation(SD)values of the paraspinal muscles,volume CT dose index(CTDIvol),and dose length product(DLP)before and after CE-Boost were measured and recorded.The signal-to-noise ratio(SNR),contrast-to-noise ratio(CNR),effective dose(ED)of each blood vessel before and after CE-Boost were calculated.Subjective image quality was analyzed by two senior radiologists using a five-point scale in a double-blinded method.Statistical analysis was performed using paired t-test and Wilcoxon test.Results The CT values of each area with CE-Boost images were significantly higher than those without CE-Boost images(P<0.001).SNR and CNR of each blood vessel with CE-Boost images were significantly higher than those without CE-Boost images(P<0.001).The subjective scores of both images were above 3 points,which met the requirements of clinical diagnosis with good consistency(Kappa=0.772,0.697).The median subjective scores of images with CE-Boost were 5(5,5),which were significantly higher than those without CE-Boost images 5(5,4),(P=0.002).CTDIvol,DLP and ED were(1.85±1.12)mGy,(94.66±44.68)mGy·cm and(1.42±0.67)mSv,respectively.Conclusion CE-Boost technique can significantly improve the image quality of portal vein CTV with low dose and low contrast media usage.