1.Design of a production machine of radioisotope capsule
Rongchuan XIAO ; Shouqiang CHEN
Chinese Journal of Tissue Engineering Research 2008;12(26):5181-5184
A newly developed production machine was introduced, which was used to produce radioisotope capsule for medical treatment. The machine can produce radioisotope capsule at different dose for treating different patients. Also, the machine can do real time detection to the production and automatically record information during production. The exploitation of the equipment avoids the side effects of using liquor radioisotope.
2.Purification and molecular configuration primary analysis of free radical scavenging substances in antarctic ice alga Berkeleya rutilans H-15
Zhou ZHENG ; Jinlai MIAO ; Hao CHEN ; Shouqiang WANG
Chinese Journal of Marine Drugs 1994;0(01):-
Objective To study on quenching free radical substances in antarctic ice alga.Methods Antarctic ice alga Berkeleya rutilans H-15 used as material,complete experiment of preparation free radical scavenging substances was established.All of these include the extraction of active substances by methanol,then pursuing and determination of the separation effect and change of active substances by DPPH and Godin method;the primary separation and purification by silica gel 60 column chromatogram;the farther purification by Sephadex LH column chromatogram and the purity determination of compound by HPLC.The type of compound and functional group of high pure compound were determined by the IR spectrum,HPLC-MS.Results One pure compound with strong activity was obtained from Berkeleya rutilans H-15,and it was confirmed to belong to phenol derives by analysis of IR spectrum and HPLC-MS.Conclusion It was completely feasible to find and acquire quenching free radical substances in antarctic ice alga,which initiated a new way to obtain natural antioxidant active substances from antarctic microorganism.
3.Low-Field-MRI in Assessing the Vessels Surrounding Pancreas Involved by Pancreatic Carcinoma
Shouqiang JIA ; Yongxiu WANG ; Qingguo LI ; Ying CHEN ; Na LI ; Huizhen SUN
Journal of Practical Radiology 2001;0(08):-
Objective To study the accuracy,clinical value and limit in assessing the vessels surrounding pancreas involved by pancneutic carcinoma with low field MRI.Methods MRI scanning was performed in 55 patients with pancreatic carcinoma.We prospectively evaluated the MRI findings of vascular involvement by pancreatic carcinoma,and compared with the surgical results.Results Of total 55 cases,50(91%)cases were correctly diagnosed on MRI .MRI carries an accuracy of 86% for prediction of resectility,and accuracy of 93% for unresectility.Conclusion Low field MRI can accurately assess the peripancreative vessels ,but it has limited value in the patients with pancreatic carinomaⅠa orⅠb.
4.Design and application of user managing system of cardiac remote monitoring network.
Shouqiang CHEN ; Jianmin ZHANG ; Feng YUAN ; Haiqing GAO
Journal of Biomedical Engineering 2007;24(6):1230-1232
According to inpatient records, data managing demand of cardiac remote monitoring network and computer, this software was designed with relative database ACCESS. Its interface, operational button and menu were designed in VBA language assistantly. Its design included collective design, amity, practicability and compatibility. Its function consisted of registering, inquiring, statisticing and printing, et al. It could be used to manage users effectively and could be helpful to exerting important action of cardiac remote monitoring network in preventing cardiac-vascular emergency ulteriorly.
Electrocardiography, Ambulatory
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instrumentation
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methods
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Humans
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Monitoring, Ambulatory
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instrumentation
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methods
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Remote Consultation
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methods
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Software Design
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Telemedicine
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instrumentation
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methods
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User-Computer Interface
5.Research progress in early-stage lung cancer risk assessment methods based on artificial intelligence
Yali TAO ; Yang CHEN ; Shouqiang JIA ; Shengdong NIE
International Journal of Biomedical Engineering 2023;46(6):575-580
Lung cancer is one of the most serious malignant tumors threatening human health. Early detection and accurate risk assessment are crucial for improving the survival rate and prognosis of lung cancer patients. In this review paper, the research progress in early-stage lung cancer risk assessment methods based on predictive factors and medical imaging was summarized. The results indicated that by utilizing more diverse machine learning algorithms and larger-scale datasets, independent risk prediction factors can be further mined to achieve an accurate assessment of individual lung cancer risk.
6.Progress on research of CT radiomics in response assessment of non-small cell lung cancer
Zijuan HAN ; Yang CHEN ; Yifeng YANG ; Jing GONG ; Shouqiang JIA ; Shengdong NIE
Tumor 2023;43(8):692-700
Radiomics is a non-invasive method to extract valuable features from computed tomography(CT)images to characterize the correlation between tumor phenotype and clinical treatment outcomes,which is of great significance in the evaluation of the efficacy of non-small cell lung cancer(NSCLC).This paper reviews the research methods of CT Radiomics in the evaluation of curative effect of NSCLC.Firstly,the research content of CT radiomics in NSCLC is summarized.Then,from the perspective of different treatment methods,such as namely radiotherapy and chemotherapy,targeted therapy and immunotherapy,the research methods of CT radiomics in the evaluation of NSCLC efficacy were summarized,and the CT radiomics was compared with other commonly used efficacy evaluation systems.Finally,the development trend and improvement of the application of CT radiomics in the evaluation of NSCLC curative effect were summarized and prospected.
7.Progress in TN staging of rectal cancer based on multimodal magnetic resonance imaging
Jing SUN ; Yang CHEN ; Xuewen HOU ; Jing GONG ; Tong TONG ; Shouqiang JIA ; Shengdong NIE
International Journal of Biomedical Engineering 2023;46(1):66-73
Rectal cancer is one of the most common gastrointestinal malignancies in China. Accurate and reasonable assessment of the preoperative staging of rectal cancer can significantly enhance treatment outcomes and improve patient prognosis. Magnetic resonance imaging is the technique of choice for local staging of rectal cancer and has significant advantages in the diagnosis of rectal primary tumors (T) and peri-intestinal lymph nodes (N). In this review paper, the research ideas and progress of traditional radiomics and deep learning methods for preoperative TN staging prediction of rectal cancer were reviewed around multimodal magnetic resonance images, with the aim of providing new ideas for realizing fully automated TN staging algorithms for rectal cancer.
8.Investigation and analysis of characteristics and mobility of the overlapping population of voluntary blood donation and plasmapheresis donation
Wan LI ; Guanglin XIAO ; Changqing LI ; Yongjun CHEN ; Yong WANG ; Jing HUANG ; Xiaojun MA ; Shouqiang YANG ; Fei CHEN ; Baolin HOU ; Ya WANG
Chinese Journal of Blood Transfusion 2023;36(8):710-712
【Objective】 To analyze the characteristics and mobility of the overlapping population of voluntary blood donation and plasmapheresis donation, so as to provide a scientific basis for the formulation of recruitment and retention strategies for blood donation and plasmapheresis donation, and to further propose a scientific reference for the decision-making of blood banks and plasmapheresis station management in China. 【Methods】 The basic information of blood donors and plasmapheresis donors in two counties in Guangyuan, Sichuan Province, which carried out whole blood collection and plasmapheresis collection from the establishment of the station to July 31, 2021 was statistically compared and analzed using the chi-square test and Post hoc testing test. 【Results】 As of July 31, 2021, a total of 50 658 people participated in blood donation and 63 375 people participated in plasmapheresis donation in Jiange County and Cangxi County, with a total overlap of 6 189 people. In the two regions, 16 458 (35.2%) people aged 40 to 50, and 35 558 people (56.1%) were over 50 years old. Among the overlapping population, 2 496 (40.3%) were 40 to 50 years old, accounted for the largest proportion, and 3 146 (50.8%) were males. Significant differences were noticed in age (P<0.001) and gender (P<0.001). There was a shift in dontion in 5 183, including 2 072 people from plasma to blood and 3 111 people from blood to plasma, among which 2 671 (51.5%) were men and 3 632 (70.1%) were over 50 years old, with significant differences in gender (P<0.05) and age (P<0.001). 【Conclusion】 There were a small number of donors donating both blood and plasma in Jiange and Cangxi, and men aged 40 to 50 were the majority, and people over 50 years old were more likely to shift the donation goals. The vast majority of donors have a single and fixed donation goal (blood or plasma), and are not easy to change.
9.Analysis of the impact of setting up plasmapheresis station on the collection volume of voluntary blood donation based on panel vector autoregressive model
Wan LI ; Guanglin XIAO ; Changqing LI ; Yongjun CHEN ; Yong WANG ; Jing HUANG ; Xiaojun MA ; Shouqiang YANG ; Fei CHEN ; Ya WANG
Chinese Journal of Blood Transfusion 2023;36(7):618-622
【Objective】 To analyze the dynamic relationship between the setting up of plasmapheresis station and the volume of voluntary blood donation collected using panel vector autoregressive model, so as to provide scientific reference for the management policies of blood stations and plasmapheresis stations in China. 【Methods】 The data collected from blood stations in seven administrative regions of Guangyuan, Sichuan Province from 2011 to 2021, as well as plasma collection data from two plasmapheresis stations in the region within two years since their operation, were collected. A panel vector autoregressive model was constructed. Impulse response analysis and variance decomposition analysis were used to analyze the impact and time lag effects of simulated plasmapheresis station settings on the collection volume of voluntary blood donation. Covariance analysis was used to explore whether the establishment of plasmapheresis station had an impact on the volume of voluntary blood donation collected after excluding the impact of initial value differences. 【Results】 The pulse response results showed that after the plasmapheresis station was set up, there was a negative impact effect on the voluntary blood donation collection volume at the first stage, and its impact began to rise after the second stage, reached the highest value in the third stage, and then began to decline. After the seventh stage, it tended to be stable. However, within the 10 stage range, the confidence interval for the response strength of voluntary blood donation collection volume always included 0, indicating that the response of blood collection volume to the plasmapheresis station setting in the region was not statistically significant. The results of variance decomposition showed that the contribution of collection volume of voluntary blood donation to their own impact reached 94.3%. In terms of the contribution of plasmapheresis station factors, the number of plasma donors has a relatively greater impact on the volume of voluntary blood donation collected(2.2%). Covariance analysis showed that after removing the initial confounding factors, whether to establish a plasmapheresis station had no significant impact on blood donation volume in the two groups of regions (P>0.05). 【Conclusion】 The establishment of a new plasmapheresis station will have a certain impact on blood collection volume of blood stations in the region in a short term, but in the long term, it may not directly affect the voluntary blood donation collection in the region.