Objective To investigate the result of detethering operation for the hydrops of upper urinary tract caused by tethered cord syndrome (TCS). Methods A retrospective study was carried out on 20 cases of TCS treated by detethering operation. The main parameters were compared pre-and postoperation on postvoiding residual volume, kidney and ureter of B-ultrasonograph and renal function of serum biochemicals. Results The postvoiding volume resumed normal in 5 cases,decreased in 10 cases.The effective rate was 83%.The hydronephrosis was obviously improved in 6 cases,mild in 7 cases and unchanged in 7 cases.The rate of improvement was 65%.The hydroureterosis was markedly effective in 7 cases,partial in 4 cases,unchanged in 7 cases.The rate of effect was 61%.Renocortical thickness was evident increase in 5 cases,alleviate increase in 2 cases and unchanged in 13 cases.The rate of increase was 35%.2 cases of moderate uremia was transformed to mild and 4 cases of mild uremia was changed to normal. Conclusions The detethering operation is rational and effective for hydrops of upper urinary tract and uremia caused by TCS.

Purpose:To study the determining prognostic factors that affect the survival of patients with bilateral breast cancer. Methods:The records of 21 women with bilateral breast cancer were analyzed.4(19%) presented simultaneous bilateral tumor.17(81%)developed bilateral breast cancer with interval in between. Patients were treated with surgery, radiation treatment and chemotherapy. Analysis of high risk factors of breast cancer and possible relation to postoperative survival was carried out.Results:The size of the tumor, the number of involved axillary nodes, and the adequacy of the initial treatment still remain the major prognostic factors ,correlated with the time interval between two cancers. 2 year, 5 year, 10 year, survival was recorded to be 90%, 71.4%, 66.7%. Conclusions:If treatment is correct for bilateral breast cancers, its 5 year survival rate still rather high. Time interval between two breast cancers was the most prominent prognostic factor, correlated with the overall survival. The early diagnosis and prompt adequate treatment of the seconed primary breast cancer are still the key to longer survival rates of bilateral breast cancer.