1.Analysis of postoperative complications and their related factors after laparoscopic-assisted radical surgery in rectal cancer
Zuoliang LIU ; Tong ZHOU ; Xiaobo LIANG ; Chongshu WANG ; Shoujiang WEI ; Junjie MA ; Guangjun ZHANG
Cancer Research and Clinic 2014;26(8):527-530
Objective To investigate the factors associated with postoperative complications after laparoscopic-assisted radical surgery in rectal cancer.Methods The clinical data of 310 patients with rectal cancer performed by laparoscopic-assisted radical resection from November 2010 to August 2013 were analyzed retrospectively.The differences between patients with and without postoperative complications were compared.All the data were analyzed by the t test,chi-square test or Logistic regression analysis.Results Among the 310 patients,postoperative complication occurred in 80 patients.On univariate analysis,postoperative complication was associate with gender,age,body mass index,preoperative comorbidity,diameter and location of tumor,TNM staging,operative time and surgeon experience (all P < 0.05).Logistic regression analysis revealed that gender,body mass index,preoperative comorbidity,location of tumor,TNM staging and surgeon experience were independent risk factors for postoperative complications (all P < 0.05).Follow-up was available in 260 patients,with a median follow-up of 18 months (3-30 months).Differences in survival rates between patients with and without postoperative complications were no statistical significance (x2 =1.201,P =0.273).Conclusions Gender,body mass index,preoperative comorbidity,location of tumor,TNM staging and surgeon experience are independent risk factors for postoperative complications in laparoscopic-assisted radical surgery for rectal cancer.The short and medium-term survival time between patients with and without postoperative complications are similar.
2.Re-evaluation on preparation technology of compound Chuanxiong dropping pills
Wei ZHANG ; Yan WEI ; Shoujiang MA
Journal of Pharmaceutical Practice 2015;(1):60-62
Objective To optimize the preparation technology of compound Chuanxiong dropping pills .Methods Ratio of intermediate material to matrix ,dripping temperature and condensate temperature were used as factors ,with spherical de‐gree ,pill weight variatcon ,dissolve time limit coefficient and appearance quality as indexes ,the forming technology of compound Chuanxiong dropping pill was optimized by orthogonal test .The dropping preparation technology was optimized using dropping distance ,dropping speed as factors .Results The optimal preparation conditions were as follows:ratio of intermediate material to matrix was 1:2 ,dropping temperature was 80 ℃ ,temperature of condensate was 15‐20 ℃ ,dropping distance was 5 cm , dropping speed was 40 drops/min .Conclusion The preparation technology was reasonable ,simple and easy to control for the preparation of compound Chuanxiong dropping pills .
3.Therapeutic experience of type Ⅲ-b congenital intestinal atresia.
Dong MA ; Dengming LAI ; Xiaoxia ZHAO ; Shuqi HU ; Chengjie LYU ; Shoujiang HUANG ; Qi QIN ; Jinfa TOU
Journal of Zhejiang University. Medical sciences 2019;48(5):487-492
OBJECTIVE:
To summarize the clinical characteristics and treatment of type Ⅲ-b congenital intestinal atresia (CIA).
METHODS:
The clinical data of 12 type Ⅲ-b CIA treated in the Children's Hospital of Zhejiang University School of Medicine from January 2015 to December 2017 were analyzed retrospectively.
RESULTS:
Of the 12 patients diagnosed as type Ⅲ-b CIA in operation, treatment was refused during operation by their parents in 2 cases. For one child, only the proximal intestine was partly resected in the first operation, dilatation and dysplasia of the duodenum was diagnosed and total duodenum was resected and sutured in the second operation, as the child had postoperative intestinal obstruction. For one child, due to the long distal normal intestine, distal apple-peel like intestine was partly resected without mesenteric reformation. For the rest 8 children total duodenum resection and mesenteric reformation were performed. During the postoperative follow-up, one case was early rejected for further treatment by parents, one case died from complex congenital heart disease, 5 cases had the complication of short bowel syndrome. All 8 survival children received parenteral nutrition support after operation, 5 of whom received parenteral nutrition support for more than 42 days, and they were followed up for 1-3 years after discharge. The short-time efficacy was satisfactory.
CONCLUSIONS
For children with type Ⅲ-b CIA, the distal apple-peel like intestine should be preserved as much as possible, the mesenteric reformation should be performed and the proximal dilated bowel should be partly resected and sutured. Postoperative nutritional support and early intestinal rehabilitation contribute to the compensation for rest intestines.
Child
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Humans
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Intestinal Atresia
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complications
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surgery
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therapy
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Intestines
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surgery
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Parenteral Nutrition
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Retrospective Studies
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Short Bowel Syndrome
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complications
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Treatment Outcome