The changes of marginal epithelial cells in corneal wound healing were observed in a rabbit. The randomly assigned three eyes in the rabbits were extracted at first, third, and eighteenth day after full thickness epithelial removal, then observed under the electronmicroscope. At the 1st and 3rd day ,the thickness of the epithelium at the wound margin was reduced at the leading edge. These flattened epithelial cells showed ruffling and folding of the plasma membrane near free edge to form filopodia or lamellipodia processes, extending onto wound surface. Cytoskeletons reorganized and rearranged in leading edge. Basement membrane of the wound was relatively intact, but on which cellular debris were observed, and cell migration undergone and hemidesmosomes developed incompletely. In eighteenth day, basal cell recovered original cylindric shape, cytoskeletons was originally redistributed in cytoplasm after migratory phase, and hemidesmosome developed completely.
Basement Membrane ; Cell Membrane ; Cell Movement ; Cytoplasm ; Cytoskeleton ; Epithelial Cells* ; Epithelium ; Hemidesmosomes ; Pseudopodia ; Rabbits ; Wound Healing* ; Wounds and Injuries*

Clear lens extraction and implantation of posterior chamber intraocular lens was performed on 12 eyes(7 patients) to correct high myopia. Average preoperative refractive error(spherical equivalent) was -19.08D with a range of -13.00D to -31.00D. 7 eyes(58.3%) achieved 0.5 or better uncorrected postoperative visual acuity and all eyes achieved 0.5 or better corrected visual acuity. In postoperative refractive errors, 4 eyes(33.3%) were 1.0D of emmetropia and 8 eyes(66.6%) were within 2.0D. In conclusion, clear lens extraction and posterior chamber intraocular lens implantation is a more favorable technique for correcting high myopia, but further study for complications such as retinal detachment, cystoid macular edema, and posterior capsular opacity and for precise results is needed.
Emmetropia ; Lens Implantation, Intraocular ; Lenses, Intraocular ; Macular Edema ; Myopia* ; Refractive Errors ; Retinal Detachment ; Visual Acuity