No abstract available.
Shock, Septic*

No abstract available.
Shock, Septic*

No abstract available.
Shock, Septic*

Severe sepsis and septic shock is a life-threatening disease. It is combined with multi-organ failure. In the past decade, early goal directed therapy has been proposed as an effective treatment strategy for better outcome. Recent epidemiologic studies showed that the outcome of sepsis has been improved with the introduction of early goal directed therapy. However, it is unclear which elements of early goal directed therapy contributed to the better outcome. Recent prospective and randomized trials suggested that some elements of early goal directed therapy did not have any effect on the outcome benefit. In this paper, recent articles about early goal directed therapy will be reviewed and the effectiveness of individual elements of early goal directed therapy will be discussed.
Sepsis* ; Shock, Septic

The study included 49 patients from 1 month to 15 years old who had diagnosis of septic shock and treated at ICU of the National Hospital of Paediatrics. The result showed that: group of age<5 years is 71.4%; The male/female ratio is 2.06/1. Patients admitted to hospital from April to June (42.8%). About 90% of cases have local infections such as respiratory infection (34.7%), gastrointestinal infection (24.5%), skin, musle and bone infections (22.4%). All of them have uncompensated shock with symptoms of poor tissue perfusion and hypodynamic; disorded status (100%); cool extremities (91.8%); refill>3 seconds (100%); drop blood pressure (69.4%); weak pulse (71.4%), oliguria and anuresis (100%) and CVP<5 cmH2O (51.2%)
Shock, Septic, Child, Diagnosis

Summary Staphylococcal toxic shock syndrome (TSS) is a clinical disease with acute onset of fever, rash, hypotension and multi-organ system involvement. Staphylococcal scalded skin syndrome (SSSS), mostly described in neonate and children, is a superficial blistering disease caused by the exfoliative toxin of specific strains of Staphylococcus aureus. TSS and SSSS rarely occur concurrently in adults. We here describe a 35-year-old woman who was initially referred to dermatology team as toxic epidermal necrolysis. She presented with a rapid epidermal detachment without mucosal involvement, fever and shock, associated with acute kidney injury and transaminitis, severe metabolic acidosis, complicated by COVID-19 infection, and finally succumbed within 36 hours of hospitalization. Early recognition and prompt treatment are the key factors in the management as TSS itself can lead to mortality. Staphylococcal TSS and SSSS are important differential diagnosis to consider in acute epidermal detachment, as not all cases are drug-induced.
Staphylococcal Infections ; Shock, Septic

No abstract available.
Adolescent* ; Humans ; Male* ; Shock, Septic*

Background: Septic shockis often seen in severe disease to be hospitalized at Intensive Care Unit. In America, there are about 400,000 infection cases in which 20% to 40% develop into septic sock. Objectives:This study aims to find out some prognostic factors of death in treatment of septic shock in children. Subjects and method:A prospective and descriptive study was conducted on 67 patients suffering from septic shock based on \u201cThe 2002 American College of Critical Care Medicine/Society of Critical Care Medicine \ufffd?combined with standard of 1993 National conference on Intensive care whom admitted Intensive care unit of National Hospital of Pediatrics (N.H.P) Results:The severity of shock affecting mortality rate [OR=33.0; 95% CI (6.6 - 163.0), P < 0.001]. The delay of shock diagnosis significantly affected the results of treatment and mortality rate [OR= 52.0; 95% CI (5.8 - 446.0); p < 0.001]. The severity of acidosis has affected on results of treatment and mortality rate [OR= 4.00; p<0.05]. The blood lactate of > 5.5 mmol/l indicated a bad prognosis and high mortality risk; Se 79%, Sp 52%, AUC 0.75%. The lactate level affected the mortality rate [OR = 10.0; 95% CI (1.9 - 62.0); p < 0.05]. Conclusion: The factors effected to the treatment results and mortality risk consisted of severe sock level, late diagnosis, infected severe high lactate concentration.
Shock ; Septic/ diagnosis ; mortality ; Child

The study encountered 16 patients of 1 to 12 years. Admitted to the intensive care Unit of the IPCH. With clinical manifestations septic shock. The patients were given Dopamine (10mcg/kg/min) after adequate fluid repletion of volume 36ml/kg for one hour. But clinical responses were not satisfactory. Results: The manifestation of tissue perfusion showed markedly improved one hour following giving dopamine: disappearing of mottle on the skin and of cooling of the extremities and increasing pulse strength. Improving blood pressure. Increasing diuresis and no change of central venous pressure observed following dopamine from 1 to 5 hour
Shock, Septic ; Therapeutics ; dopamine ; Child

Study on 2 subject groups: control group including 48 healthy persons and case group: 34 patients (20 male, 14 female) with septic shock, all of them treated at Bach Mai Hospital from January 2003 to November 2003, aged from 16 to 75 year old. Subjects in control group underwent clinical and Doppler ultrasound examinations, had medical records. In case group, patients underwent clinical and paraclinical examinations for diagnosis and treatment followed by regime of the department. Results: 15/34 septic shock patients have cured and discharged (44.1%), 19 patients died (55.9%). At the first stage of septic shock, cardiac output (CO) and cardiac index (CI) increased (CO=6.461.85L/min; CI=4.351.24L/min/m2) but ejection fraction decreased (EF=50.69.27%), with 13 patients had EF<50% (38.2%). Before treatment, the CO and EF of survival group were lower than the dead group. During treatment, end-diastolic left ventricular volume increased along with EF, and heart rate reduced gradually to normal in survival group. These changes weren’t observed in the dead group.
Shock ; Septic ; Ventricular Function ; Left