Objective To study intermediate and long term efficacy of uterine arterial embolization (UAE)with sodium alginate microspheres(KMG)at diameters 500-700μm in treatment of diffuse adenomyosis.Methods Totally 40 patients with standard difluse adenomyosis were enrolled and treated with UAE.KMG at diameters 500-700 μm for vascular embolization were used to embolize the arteries.The degree of dysmenorrhea,amount of menorrhea and uterine volume,as well as the level of serum CA125,follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E2)were investigated before andafter UAE.Results The follow up rates were 100%(40/40),100%(40/40),80%(32/40),68%(27/40),58%(23/40)after uterine arterial UAE 12,24,36,48 and 60 months respectively.The early,intermediate and long-term effective rates were 90%(36/40),88%(28/32),83%(19/23).The degree of dysmenorrhea,the amount of menorrhea and the uterine volume,as well as serum CA125 all decreased significantly 3 mouths after UAE at varying degrees(P＜0.05).Compared with other follow-up time,thedegree of dysmenorrhea and the amount of menorrhea declined to their lowest point at 6 month after UAE (P＜0.01).Paralleled with the decrease of volume of uterine,serum CA125 also decreased significantly and reached the lowest level 12 months later compared with other follow-up times(P＜0.01).Even at the 12th month after UAE serum CA125was not normal and FSH,LH and E2 did not change all the times after UAE(P>0.05).No recurrence was found during the 60 months after UAE.Condusion KMG used in UAE at diameters 500-700 μm has good intermediate and long term effectiveness in treatment of diffuse adenomyosis with no side effects.

Objective To explore the effects of humanistic care on preoperative negative emotions in patients undergoing eye surgery, so as to alleviate the negative emotion and promote the rehabilitation process of the operation. Methods From October 2016 to February 2017, totals of 120 patients who were undergoing eye surgery from each of the 2 wards of the ophthalmology department in the First Affiliated Hospital of Zhengzhou University were recruited in the research. All the patients were randomly divided into control group and observation group by coin tossing method. Routine nursing was applied in the control group, while on the basis of the control group, humanistic care was given to the observation group. The intervention effects were evaluated by the general information questionnaire, the Self-Perceived Burden Scale (SPBS), Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS). Results There was no statistical difference in negative emotions between the two groups before intervention (P>0.05). The scores of negative emotions all had a certain decrease after intervention. The scores of SPBS, SAS and SDS were (28.49±5.92), (45.49±6.49) and (41.22±5.62) in the observation group after intervention respectively; while those scores were (34.95±6.56), (58.57±8.56) and (54.53±6.45) in the control group respectively. The scores of the observation group were all lower than those of the control group, and the differences were statistically significant (t=10.49, 6.45, 7.34; P< 0.01). Conclusions Humanistic care can obviously reduce patients' self-perceived burden, anxiety, depression and improve patients negative emotions.