Objective To investigate the influence of bifidobacterium on inflammatory response of brain traumatic injury patients.Methods According to the sequence of patients'admission time,a total of 60 patients with traumatic brain injury were randomly divided into the research group and the control group,30 cases in each group.The research group was fed intestinal nutrient solution combined with bifidobacterium,and 1 × 108cfu/d bacteria every day.The control group was skimpily given enteral nutrient solution.The WBC counts,C-reactive protein (CRP) and interleukin-6 (IL-6),GCS score and infection status,ICU length of stay and 30 days mortality in the 1 st,5th,10th,15th day of enteral nutrition were recorded by health care professionals.Results The leukocyte count,CRP and inflammatory factors IL-6 of the research group were significantly lower than those in the control group in the 15th day of enteral nutrition[(8.02 ± 2.47) × 109/L vs (10.54 ± 3.98) × 109/L,(28.02 ± 9.43) mg/L vs (70.54 ± 13.92) mg/L,(61.02 ± 22.43) ng/L vs (83.52 ± 14.94) ng/L; t =5.474,6.231,9.343,P =0.029,0.049,0.001] ;The GCS score of the two groups gradually increased,and which of the first 10 days had no significant differ ence between the two groups.In the 15th day of enteral nutrition,GCS score of the research group was significantly higher than the control group [(12.02 ± 2.12) point vs (10.12 ± 4.94) point,t =9.744,P =0.000].The incidence rate of infection of research group was significantly lower than that of the control group,but ICU length of stay shortened (16/30 vs 27/30,x2 =9.610,P =0.002).No significant difference was observed in 30-day mortality between the two groups.Conclusion Adding an appropriate amount of probiotics in enteral nutrition on regular basis can significantly reduce the body's inflammatory response and the incidence of infection in patients,shorten hospitalization days.

Objective To evaluate the angiographic findings and the therapeutic effect of thrombolysis in AMI (acute myocardial infarction) patients. Method A retrospective study were carried out in consecutive eighty-four inpatients with AMI treated with intravenous thrombolysis and coronary angiography was taken within a week after illness onset from January 2000 to August 2007. The patients were divided into successful recanalization group and non-recanalization group. Single factor χ2 test and multi-factor logistic regression analysis were applied to observe the relationship among the angiographic features of IRA (infarct-related artery including the number of stnosis, the location of stenosis, the severity of stenosis and the morphological changes) and treatment effect of intravenous urokinase thrombolysis. Results (1) Single factor χ2 test showed that location and the extent of lesion of IRA were eligible to enter the logistic regression formula (P ＜ 0.05),whereas the number of lesions and the severity of IRA's stenosis were not eligible to enter the logistic regression formula (P ＞ 0. 05). (2) Multi-factor logistic regression analysis showed that the extent of lesion of IRA was the only factor that had a negative impact on the therapeutic effect of intravenous thrombolysis.Conclusions The study shows that the extent of lesion of IRA is the only factor that has a negative impact on the therapeutic effect of intravenous thrombolysis; The number, the location of lesion and the severity of stenosis of IRA have no impact on the therapeutic effect of intravenous thrombolysis in AMI.