1.Recognition and Practice of Traditional Chinese Medicine in Intestinal Graft-Versus-Host Disease
Yiwen FANG ; Shisi SHAO ; Baodong YE
Journal of Zhejiang Chinese Medical University 2024;48(9):1110-1115
[Objective]To summarize Professor QIN Danping's experience in applying traditional Chinese medicine to treat intestinal graft-versus-host disease.[Methods]Through following Professor QIN's outpatient service,collecting and sorting out medical cases,the academic characteristics of Professor QIN in treatment of intestinal graft-versus-host disease were summarized from the aspects of disease cognition,syndrome evolution and clinical treatment,and the medical cases were attached to support it.[Results]It is believed that the patient of transplant is the subject,the transplanted allogeneic hematopoietic stem cells are the objects and spleen deficiency is the basis.After transplantation,the object enter the body to produce dampness,heat,cold,stasis and toxin,which act on the intestine to cause disease.The pathogenesis of the disease is root deficiency and branch excess.Treatment emphasizes both symptoms and root causes,invigorating the spleen and supplementing Qi is basic treatment principle,dispelling dampness,regulating cold and heat,regulating Qi and dissolving stasis are manifestations,to make the vital Qi and evil Qi mutually inclusive and the disease achieve stable.The medical cases mentioned were acute gastrointestinal graft-versus-host disease and chronic intestinal graft-versus-host disease,were treated by strengthening the spleen and clearing dampness-heat,harmonizing stomach and stopping diarrhea,regulating cold and heat,strengthening the spleen to control diarrhea separately,and both cases achieved significant effect.[Conclusion]Professor QIN aims at making the ontology and foreign body mutually inclusive,adopts"strengthening the body resistance and resolving pathogen"as the core in the treatment of intestinal graft-versus-host disease,improves clinical symptoms and alleviates the intestinal mucosal inflammation,which is worth further exploration.
2.Cryptogenic Multifocal Ulcerous Stenosing Enteritis Treated by Integrated Traditional Chinese and Western Medicine: A Case Report
Lu XU ; Danping QIN ; Shisi SHAO ; Yao HUANG ; Qiang YANG
Journal of Traditional Chinese Medicine 2024;65(9):970-975
Cryptogenic multifocal ulcerous stenosing enteritis(CMUSE) is a rare and difficult disease characte-rized by chronic recurrent intestinal obstruction and gastrointestinal bleeding caused by multiple ulcers and strictures of the small intestine. There is still a lack of mature and systematic guidance for the treatment of the disease. This paper reported a case of CMUSE mainly manifested as fatigue, abdominal distention, and edema of both lower limbs , who is treated by integrated traditional Chinese and western medicine. In western medicine treatment, hormone and symptomatic treatment are mainly used. In traditional Chinese medicine treatment, the method of fortifying spleen and reinforcing healthy qi is taken as the basis; during the active stage of the disease, the method of moving qi and removing stagnation, clearing and removing dampness and heat, astringing and engendering flesh should be combined with, while during the remission stage, it is advised to unite with the method of diffusing lung and moving water, regulating and harmonizing zang-fu (脏腑) organs; simultaneously, replenishing qi and invigorating blood can be used throughout the treatment, and attach importance to the maintenance therapy of the traditional Chinese medicine immunomo-dulatory agent Tripterygium glycosides. After more than 2 years of treatment, the patient's clinical symptoms were significantly relieved, and all indicators basically restored to normal, having a stable condition.