1.Erratum: Prescribing Patterns of Codeine among Children under aged 12 in Korea.
Hyo Ju PARK ; Han Na SHIN ; Ju Young SHIN
Korean Journal of Clinical Pharmacy 2016;26(1):96-96
Erratum agreed to by all authors, editor in chief, publisher, and scientific society.
2.Clinical Review of Ten Years' Pediatric Surgical Diseases.
Soo Jin Na CHOI ; Sang Young CHUNG ; Shin Kon KIM
Journal of the Korean Association of Pediatric Surgeons 1998;4(2):110-116
A clinical review was made on 2,191 cases of general pediatric surgery under the age of 15 years which were operated upon at the Divisionof Pediatric Surgery, Department of Surgery, Chonnam University Hospital from January 1988 to December 1997. The number of operations in pediatric age were 13,144 (13.2%) out of total 99,555 operations at Chonnam University Hospital and the most prevalent age group was under 1 year of age (14.3%). The number of operations in Divisionof General Pediatric Surgery were 2,191 (16.7%) out of total 13,144 operations in pediatric age and the incidence of patients under 1 year of age in general pediatric surgery was 42.9% (941/2,191). The prevalent diseases under 1 month of age were anorectal malformations (20.6%) and hypertrophic pyloric stenosis (20.3%) and between 1 month to 1 year of age were inguinal hernia (32.4%) and intussusception (19.6%). The total motality rate in neonatal intensive care unit was 31.3%. Gastroschisis presented highest mortality.
Gastroschisis
;
Hernia, Inguinal
;
Humans
;
Incidence
;
Infant, Newborn
;
Intensive Care, Neonatal
;
Intussusception
;
Jeollanam-do
;
Mortality
;
Pyloric Stenosis, Hypertrophic
3.Implementing a Sepsis Resuscitation Bundle Improved Clinical Outcome: A Before-and-After Study.
Jeongmin KIM ; Sungwon NA ; Young Chul YOO ; Shin Ok KOH
Korean Journal of Critical Care Medicine 2014;29(4):250-256
BACKGROUND: Unlike other diseases, the management of sepsis has not been fully integrated in our daily practice. The aim of this study was to determine whether repeated training could improve compliance with a 6-h resuscitation bundle in patients with severe sepsis and septic shock. METHODS: Repeated education regarding a sepsis bundle was provided to the intensive care unit and emergency department residents, nurses, and faculties in a single university hospital. The educational program was led by a multidisciplinary team. A total of 175 adult patients with severe sepsis or septic shock were identified (88 before and 87 after the educational program). Hemodynamic resuscitation bundle and timely antibiotics administration were measured for all cases and mortality at 28 days after sepsis diagnosis was evaluated. RESULTS: The compliance rate for the sepsis resuscitation bundle before the educational program was poor (0%), and repeated training improved it to 80% (p < 0.001). The 28-day mortality was significantly lower in the intervention group (16% vs. 32%, p = 0.040). Within the intervention group, patients for whom the resuscitation bundle was successfully completed had a significantly lower 28-day mortality than other patients (11% vs. 41%, p = 0.004). CONCLUSIONS: Repeated education led by a multidisciplinary team and interdisciplinary communication improved the compliance rate of the 6-h resuscitation bundle in severe sepsis and septic shock patients. Compliance with the sepsis resuscitation bundle was associated with improved 28-day mortality in the study population.
Adult
;
Anti-Bacterial Agents
;
Compliance
;
Critical Pathways
;
Diagnosis
;
Education
;
Emergency Service, Hospital
;
Hemodynamics
;
Humans
;
Intensive Care Units
;
Interdisciplinary Communication
;
Mortality
;
Resuscitation*
;
Sepsis*
;
Shock, Septic
4.Study on the therapeutic effects of interferon and gamma-globulin in experimental Pneumocystis carinii pneumonia.
Dae Whan SHIN ; Dae Young KANG ; Young Ha LEE ; Young Eun NA ; Keon Jung YUN
The Korean Journal of Parasitology 1992;30(3):219-226
This study was performed to observe the therapeutic effects of interferon-gamma(IFN-gamma) and gamma-globulin(gamma-globulin) in experimental Pneumocystis carinii pneumonia of immune suppressed mice. After 9 weeks, trimethoprim-sulfamethoxazole(TMP-SMZ; 10-50 mg/mouse/day), mouse IFN-gamma(5 x 10(4) units/mouse/day) and mouse gamma-globulin(20 mg/mouse/day) were administered to the mice for 3 weeks by the experimental group. The therapeutic efficacy was evaluated by body weights, histopathologic and electron microscopic findings of the lungs, and number of P. carinii cysts by Gomori's methenamine silver stain. Body weights of the mice were significantly increased in the group of combination therapy of TMP-SMZ with IFN-gamma or gamma-globulin, and in the group of TMP-SMZ treatment (p < 0.05), however, little effect was found in the group of gamma-globulin alone. Histopathologic findings of P. carinii pneumonia were much improved in the group of combination therapy of TMP-SMZ with IFN-gamma. Treatment with either TMP-SMZ or IFN-gamma significantly reduced the number of cysts in the P. carinii pneumonia, but gamma-globulin alone was ineffective. In electron microscopic findings of P. carinii pneumonia, the number of trophozoites and cysts were reduced by treatment with either TMP-SMZ or IFN-gamma, and most of the cysts were empty or containing one or two intracystic bodies. The present results suggested, that combination therapy of TMP-SMZ with IFN-gamma had synergistic effects in treatment of P. carinii pneumonia in experimental mice.
Drug-Synergism
;
Drug-Therapy,-Combination
;
English-Abstract
;
Gamma-Globulins-administration-and-dosage
;
Interferon-Type-II-administration-and-dosage
;
Mice-
;
Trimethoprim-Sulfamethoxazole-Combination-administration-and-dosage
;
*Gamma-Globulins-therapeutic-use
;
*Interferon-Type-II-therapeutic-use
;
*Pneumonia,-Pneumocystis-carinii-therapy
;
Gamma-Globulins
;
Trimethoprim-Sulfamethoxazole-Combination
;
Interferon-Type-II
5.Reconstruction of median sternotomy dehiscence.
Jong Pil PARK ; Ji Won JEONG ; Young Jin SHIN ; Jae Hyeon YOO ; Myeong Hoon NA
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(4):666-672
Complications after a median sternotomy incision, which is used currently in most open heart surgery, are serious, although it is infrequent. Reconstruction of the sternal defect resulting from dehiscence of median sternotomy is still big challenge to the most plastic surgeons. Since vascularized greater omentum was transposed to eliminate mediastinal wound problems, many vascularized regional muscle flaps became mainstay in reconstruction of median sternotomy wound. We treated 13 patients with median sternotomy dehiscence between October of 1993 and March of 1998. In two patients, the wound problems were so confined to superficial tissue that debrided and closed primarily. Eleven patients with deep wound infection were managed with vigorous debridement of all necrotic tissues and resultant defects were covered with regional muscle flaps: rectus myocutaneous flap(3) and bilateral pectoralis advancement flap(8). We used the pectoralis major advancement flaps without counter incision at humeral insertion site and the dissections were limited only medial to the anterior axillary line to preserve the axillary fold. In five patients with larger defects, we elevated muscle and cutaneous flaps separately to make these flaps more mobile. Large portion of two rectus abdominis flaps could not survive, whereas pectoralis advancement flaps had mo special wound problems. Only one patient developed fistula due to remained wire, regardless to flap surgery.
Debridement
;
Fistula
;
Humans
;
Omentum
;
Rectus Abdominis
;
Sternotomy*
;
Thoracic Surgery
;
Wound Infection
;
Wounds and Injuries
6.Pulmonary paragonimiasis: CT findings.
Shin Ho KOOK ; Sang Gyeong SUH ; Sun Young NA ; Hae Su KWON ; Won Ja OH
Journal of the Korean Radiological Society 1992;28(5):711-714
Though the incidence of paragonimiasis has been remarkably decreased since 1970, it is still not a rare disease in Korea. Major problems in the diagnosis of pulmonary paragonimiasis on chest radiography are its differentiation from pulmonary tuberculosis and lung cancer. Chest radiographic findings have been described in detail, but little have been reported on CT findings. We reviewed CT findings of 10 patients with pulmonary paragonimiasis. The characteristic CT findings were similar to those on chest radiography, such as air-space consolidation (70%), nodular mass (50%), pleural effusion (40%), cystic lesion (30%), small low density within the mass (30%), linear density (20%), pneumothorax(20%), and burrow track (20%). CT depicted the cystic lesions and the burrow tracks more clearly and showed the small worm-retaining cysts within the mass that were not detectable on chest radiography. In conclusion, all of these CT findings are useful in the diagnosis of pulmonary paragonimiasis especially when differentiation from tuberculosis or lung canceris difficult on chest radiography.
Diagnosis
;
Humans
;
Incidence
;
Korea
;
Lung
;
Lung Neoplasms
;
Paragonimiasis*
;
Pleural Effusion
;
Radiography
;
Radiography, Thoracic
;
Rare Diseases
;
Thorax
;
Tuberculosis
;
Tuberculosis, Pulmonary
7.Identification and cDNA Cloning of the Leptin Receptor Long from ( OB-Rb ) from Rat Splenocytes.
Jung Hyun PARK ; Sung Kyu JU ; Shin Young NA ; Kwan Hee YOU ; Kil Lyong KIM
Korean Journal of Immunology 2000;22(1):31-38
No abstract available.
Animals
;
Clone Cells*
;
Cloning, Organism*
;
DNA, Complementary*
;
Leptin*
;
Rats*
;
Receptors, Leptin*
8.Tuberculin skin test and measles vaccination.
Mi Sung CHUNG ; Young Mi KIM ; Hyung Ja PARK ; Shin Na KIM
Journal of the Korean Pediatric Society 1993;36(4):537-542
Although the incidence of tuberculosis in Korea in general has declined in recent years, it remains an importat health problem, especially in children. Inspite of the recent controversy over the necessity of tuberculin skin test prior to measles vaccination, this brief report shows 13.8% of positive skin test at 9 and 15 months of age at the time of measles vaccination. We feel, in Korea, practicing tuberculin skin test prior to measles vaccination is good way of detecting asymptomatic infection in young age who needs preventive therapy.
Asymptomatic Infections
;
Child
;
Humans
;
Incidence
;
Korea
;
Measles*
;
Skin Tests*
;
Skin*
;
Tuberculin*
;
Tuberculosis
;
Vaccination*
9.Study on the treatment of childhood acute lymphoblastic leukemia.
Sang Oh NA ; Hee Young SHIN ; Hyo Seop AHN ; Sang Kyu PARK
Journal of the Korean Cancer Association 1992;24(3):390-400
No abstract available.
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
10.A statistical study of dermatoses in soldiers from 1987-1989.
Jin Ho CHUNG ; Jong Hee NA ; Moon Soo YOON ; Young Il CHUN ; Yoo Shin LEE
Korean Journal of Dermatology 1991;29(2):203-213
A statistical study of soldiers who visited the outpatient ciepartment of the Capital Armed Forces General Fiospital from 1987 to 1989 was performed. The results were as follows : 1. The total number of outpatients was 9969 with peak clinic visits in June(11.2%) and the lowest number of clinic visits in February(6.4% ). 2. The most frequent age was 22 years(20.7% ). Soldiers between 19 and 24 years old comprised 68.1% of total patients. 3. By rank 69.3% of the outpatients were private', 16.0% sergeant and 14,4% officers. 4. The most common dermatoses were dermatophytosis, contact dermatitis, scabies, acne, seborrheic dermatosis, urticaria, alopecia, condyloma acuminatum, verruca, folliculitis, psoriasis, insect bite reactions, pityriasis rosea, herpes zoster and corns. 5. Frequent diseases, which occured during summer season, included dermatophytosis, contact dermatitis and inser,t bites. The incidence of scabies, pityriasis prsea was increased during winter and that of psoriasis was increased during spring.
Acne Vulgaris
;
Alopecia
;
Ambulatory Care
;
Arm
;
Callosities
;
Dermatitis, Contact
;
Folliculitis
;
Herpes Zoster
;
Humans
;
Incidence
;
Insect Bites and Stings
;
Military Personnel*
;
Outpatients
;
Pityriasis
;
Pityriasis Rosea
;
Psoriasis
;
Scabies
;
Seasons
;
Skin Diseases*
;
Statistics as Topic*
;
Tinea
;
Urticaria
;
Warts
;
Young Adult
;
Zea mays