The significance of Scotch-tape anal swab technique was evaluated in three communities of Korea, one in orphanage institute and two in rural populations, from November to December, 1975. Based on the epidemiological concept that the prevalence rate of Enterobius vermicularis infection in a community as "the proportion in the population who harboured E. vermicularis at certain point of time", the present authors treated the whole surveyed population with pyrantel pamoate disregard to the results of Scotch-tape anal swab and collected pinworms expelled in stool specimens during 2 consecutive days after the chemotherapy. Although the present authors could not collect the younger adult worms less than 3.54 mm in length after chemotherapy, the positive rates of pinworm collection in three surveyed communities were 80.6%, 92.5% and 91.4% respectively whereas the positive rates of single Scotch-tape anal swab were 52.4%, 53.6% and 57.1% respectively. These results denote that results of single anal swab do not represent the prevalence rate of Enterobius infection in a community. The results of successive two anal swabs and estimation of positivity in a population using Neyman's "Best asymptotically normal estimate" revealed 62.9% in the third trial group of this study and probability of finding eggs in single slide was 0.869. Comparing with the pinworm collection rate after the chemotherapy in this group the estimated positive rate was by far lower than that of pinworm collection(89.3%). The positive results of single anal swab did not correspond to the pinworm collection in average 9.1% of anal swab positive cases and the negative results did not correspond to pinworm collection in 81.3% of anal swab negative cases, when the data from three surveyed communities were amalgamated. These results must come from the principle of anal swab that detect the terminated parasitism. With rare exceptions, the anal swab negative cases harbour relatively fewer number of Enterobius than those of positive cases. And the mean number of E. vermicularis collected from anal swab negative cases was 9.1 whereas the number in anal swab positive cases was 31.5. By analyzing the data on the relationship between bathing interval and anal swab positive conversion, it was assumed that the positive rate of anal swab in a community represent the rate of appearance of gravid female Enterobius vermicularis through anus during approximately past two days prior to examination.
parasitology-helminth-nematoda ; Enterobius vermicularis ; chemotherapy ; pyrantel pamoate ; diagnosis

Since the pattern of the frequency distribution of a parasite within a host showed an overdispersed pattern, various statistical models such as Poisson, negative binomial and lognormal distributions have been applied on the population dynamics in host-parasite relations. The observed data on the number of metacercariae of Clonorchis sinensis in a suitable intermediate host, Pseudorasbora parva which were collected from an endemic area, Juk-Rim River, Kim-Hae Goon, South Kyong-Sang Do were applied on the statistical models. The results obtained are as follows: By the calculation of the raw data, 258(94.9 percent) out of 272 fish showed positive to the metacercarial infection of C. sinensis. The mean number of metacercaria in a fish was 335.1. The standard deviation was 250.6 and the mode was observed between 250 and 299. The frequency distribution pattern of metacercariae of C. sinensis within the fish host in surveyed area was fitted to the lognormal distribution (0.05 parasitology-helminth-trematoda ; Clonorchis sinensis ; metacercaria ; Pseudorasbora parva ; frequency distribution ; host

To understand the mode of transmission in clonorchiasis, a survey was made in Kim-hae Goon, South Kyong-sang Do (=Province). The mathematical analysis of the age prevalence was done on the egg positive rates. And another analysis for the comparison was also made to the cited data from two areas, North Kyong-sang Do and Ko-yang Goon, Kyong-gi Do. Some catalytic models of H. Muench (1959) were applied to the observed age prevalence. Because the both parameters, such as force of infection(a) and loss of positivity(b) were considered to be constant for a long period in the surveyed area, the two stage catalytic model by Muench was chosen to the analysis. In the surveyed area, Kim-hae Goon where the egg positive rates were 56.2 percent and 61.2 percent (by Kim, 1974), the constant values of 'a' were found to be 0.051 and 0.089 respectively. In other words, the force of infection was 51, 89 per 1,000 susceptibles. The values of 'b' were found to be 0.006 and 0.005. This means that the rates of disappearance from egg positive cases to negative were 6 and 5 per annum per l,000 positive cases in above area. Therefore, the two catalytic curves were expressed by the following equations, y = 1.133 {e(-0.006t) - e(-0.051t)} and y = 1.047 {e(-0.005t) - e(-0.089t)} respectively. In the cases of North Kyong-sang Do and Ko-yang Goon, Kyong-gi Do where the egg positive rates of clonorchis shown as 27.7 percent and 15.2 percent by Shin (1964) and Kim (l974), the curves were expressed by y = 1.769 {e(-0.010t) - e(-0.034t)} and y = 2.857 {e(-0.020t) - e(-0.027t)} respectively. From the above mathematical analyses by age prevalence in clonorchiasis, it was considered that the mode of transmission of clonorchiasis in the surveyed area, Kim-hae Goon presented more rapid pattern than those of North Kyong-sang Do and Ko-yang Goon, Kyong-gi Do.
parasitology-helminth-trematoda ; clonorchiasis-Clnorchis sinensis ; epidemiology ; transmission

Mathematical models such as the negative binomial, Poisson and Polya-Eggenberger distributions were applied to the observed data of the number of metacercariae of Paragonimus iloktsuenensis in crab hosts, Sesarma dehaani which were collected in Hadong, South Kyong-sang Do, Korea. From the above analysis, it was found that the pattern of density of metacercariae of this lungfluke among the crab hosts was well fitted to the negative binomial distribution, rather than to the Poisson or Polya-Eggenberger distribution.
parasitology-helminth-trematode ; Paragonimus iloktsuenensis ; epidemiology ; mathematics ; metacercaria ; crab ; Sesarma dehaani

Glutathione S-transferase (28GST) with molecular mass of 28 kDa is an antioxidant enzyme abundant in Clonorchis sinensis. In adult C. sinensis, 28GST was localized in tegumental syncytium, cytons, parenchyma, and sperm tails examined by immunoelectron microscopy. C. sinensis 28GST was earlier found to neutralize bioreactive compounds and to be rich in eggs. Accordingly, it is suggested that 28GST plays important roles in phase II defense system and physiological roles in worm fecundity of C. sinensis.
Animals ; Clonorchis sinensis/*enzymology ; Glutathione Transferase/*metabolism/physiology ; Immunohistochemistry ; Microscopy, Immunoelectron ; Molecular Weight ; Support, Non-U.S. Gov't

No abstract available.
Breast Neoplasms* ; Breast* ; Oncogenes*

Isolated avulsion fracture of the tibial attachment of the posterior cruciate ligament has been thought very rare. We also had experienced only nine cases of above injury in our center during 5.5 years from January, 1976 to June, 1981. Eight cases of them were followed for an average of the thirteen months, but one of them was eliminated from the study because follow-up study was impossible for the case. The purposes of this paper are to present eight cases of isolated avulsion fracture of the tibial attachment of the posterior cruciate ligament and to discuss the causes and mechanisms of the injury and the method of screw fixation for the avulsed fracture fragment. Seven were injured by traffic accident and one by fall on the knee. All cases seemed to be injured by the force directed against the flexed knee which violently stroke the anterior surface of the proximal end of the tibia or inferior portion of the knee and drove it backwards. We found the tear of posterior capsule only in one patient who was seeming injured by extensive force. All cases were treated operatively by means of screw fixation, and excellent results were obtained in five cases, good in two, and fair in one case.
Accidents, Traffic ; Follow-Up Studies ; Humans ; Knee ; Methods ; Posterior Cruciate Ligament ; Stroke ; Tears ; Tibia

No abstract available.
Knee* ; Magnetic Resonance Imaging*

No abstract available.
Lung* ; Pneumonia*

PURPOSE: This study was designed to evaluate the clinical charateristics, surgical treatment and outcome of carcinoid tumors of the rectum. METHODS: A retrospective review of the charts of all patients treated for rectal carcinoid tumors at Kangbuk Samsung Medical Center between Jan 1989 and April 1998. Thirteen patients with rectal carcinoids tumors were treated. Follow-up data, histopathological information and surgical procedures were obtained from case notes. RESULTS: There were 10 men and 3 women. The ages ranged from 28 to 60 years (mean 41.1 years for all, 43.8 years for men and 32 years for women). Eight patients (61.5%) had no symptoms. Of the five patients, four complained of rectal bleeding (30.8%), and one complained of defecational difficulty (7.7%). Size of rectal carcinoid tumor was less than 1 cm in 7 patients (53.8%), between 1 cm and 2 cm in 2 patients (15.4%), in four patients (30.8%) larger than 2 cm. Three patients were treated in Abdominoperineal resection. Two patients underwent stapled low anterior resection. The remaining 8 patients underwent conservative resection (3 colonoscopic polypectomy and electrocauterization, 2 colonoscopic snaring biopsy, 2 transanal resection and one Mason's operation). The depth of invasion was contained within sutmucosa in 3 patients. Liver metastasis was found in 2 patients. Average follow-up time was 35.6 months. Two patients died of mutiple mestastasis (liver, bone, peritoneum) 9 and 30months later. CONCLUSION: We concluded that tumors smaller than 1 cm could be managed by local treatment whereas larger than 2 cm should be managed by radical treatment.
Biopsy ; Carcinoid Tumor* ; Female ; Follow-Up Studies ; Hemorrhage ; Humans ; Liver ; Male ; Neoplasm Metastasis ; Rectum ; Retrospective Studies ; SNARE Proteins