1.Prevalence of Chlamydia Infection in Infertile Women: Application of Polymerase Chain Reaction for Detection of Chlamydia trachomatis DNA.
Seok Hyun KIM ; Eun Kyong KIM ; Byung Chul JEE ; Chang Suk SUH ; Young Min CHOI ; Jung Gu KIM ; Shin Wong MOON ; Jin Yong LEE
Korean Journal of Obstetrics and Gynecology 2000;43(3):475-480
OBJECTIVE: Endocervical infection of Chlamydia trachomatis is one of the most common sexually transmitted diseases(STD) in women, and it usually disseminates into the upper genital tract, especially at the uterine exploration. This study was performed to investigate the prevalence rate of endocervical Chlamydia trachomatis in infertile women with the application of polymerase chain reaction(PCR) for the detection of Chlamydia trachomatis DNA. METHODS: From March, 1996 to October, 1999, endocervical swabs were obtained in 101 infertile patients at SNUH. Chlamydia trachomatis DNA was extracted and amplified by a commercially available Amplicor Chlamydia trachomatis PCR kit(Roche Diagnostics, Branch burg, USA). The clinical characteristics of infertile patients were reviewed and analyzed. RESULTS: The mean age was 31.0 years old, and the mean duration of infertility was 43.4 months. The prevalence rate of endocervical Chlamydia trachomatis in infertile patients was 4.0%(4/101). There was no significant difference in the prevalence rate of Chlamydia trachomatis infection among the different infertility factor groups: 7.1%(2/28) in tubal-peritoneal factor group, 8.3%(1/12) in cervical factor group, and 8.3%(1/12) in unexplained infertility group. Two patients suffered from chronic cervicitis. CONCLUSION: The application of PCR for the detection of Chlamydia trachomatis DNA was a rather rapid and accurate diagnostic method. Therefore, it could be recommended as a diagnostic test applicable to the routine infertility work-up.
Chlamydia Infections*
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Chlamydia trachomatis*
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Chlamydia*
;
Diagnostic Tests, Routine
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DNA*
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Female
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Humans
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Infertility
;
Polymerase Chain Reaction*
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Prevalence*
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Uterine Cervicitis
2.Maternal and Fetal Outcome of Malignancies Diagnosed during Pregnancy.
Sang Soo SEO ; Eun Kyoung CHUN ; Byoung Jae KIM ; Moon Hong KIM ; Ju Wong ROH ; Jae Won KIM ; Joong Shin PARK ; Jong Kwan JUN ; Noh Hyun PARK ; Yong Sang SONG ; Bo Hyun YOON ; Soon Beom KANG ; Hee Chul SYU ; Hyo Pyo LEE
Korean Journal of Perinatology 2000;11(4):445-454
No abstract available.
Pregnancy*
3.Transthoracic Fine Needle Aspiration Cytology of the Lung.
Min Suk KIM ; In Ae PARK ; Sun Hoo PARK ; Sung Shin PARK ; Hwal Wong KIM ; Kyung Chul MOON ; Young Ah KIM ; Hye Seung LEE ; Ki Wha PARK ; Jeong wook SEO ; Hyun Soon LEE ; Eui Keun HAM
Korean Journal of Cytopathology 1999;10(1):13-19
The authors analysed 2,653 cases of transthoracic fine needle aspiration cytology of the lung to evaluate the diagnostic accuracy and its limitation. A comparison was made between the original cytologic and the final histologic diagnoses on 1,149 cases from 1,074 patients. A diagnosis of malignancy was established in 38.3% benign in 48.1%, atypical lesion in 2.3%, and inadequate one in 11.9% of the cases. Statistical data on cytologic diagnoses were as follows; specificity 98.9%: sensitivity of procedure, 76.8%: sensitivity of diagnosis, 95.5%: false positive 5 cases: false negative 18 cases: predictive value for malignancy, 98.8%: predictive value for benign lesion, 79.5%: overall diagnostic efficiency, 87.5%: typing accuracy in malignant tumor, 80%.
Biopsy, Fine-Needle*
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Diagnosis
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Humans
;
Lung*
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Sensitivity and Specificity