No abstract available.
Enzyme-Linked Immunosorbent Assay* ; Hantaan virus*

Sensitivity to estrogen has been described previously. The clinical picture is varied with pruritus, either generalized or localued or as urticaria. The hallmark of estrogen dermatitis is the cyclic premenstrual flare. The patient reported here had cyclic erythema multiforme-like lesions and showed a positive intradermal skin test to estrogen. A 20-year-old female patient presented with a periodic 5 year duration of skin lesions on both hands. The eruption commenced in the second half of the menstrual cycle, worsened through the luteal phase but the lesion almost disappeared during menstruation. An intradermal skin test to estrone showed positive results. However, a skin test with medroxyprogesterone acetate was negative. After systemic steroid and antihistamine therapy, the lesions were found to be significantly improved.
Dermatitis* ; Erythema ; Erythema Multiforme ; Estrogens* ; Estrone ; Female ; Hand ; Humans ; Luteal Phase ; Medroxyprogesterone Acetate ; Menstrual Cycle ; Menstruation ; Pruritus ; Skin ; Skin Tests ; Urticaria ; Young Adult

The study comprises 127 inpatients with drug eruption, treated at the Department of Dermatology, Seoul National University Hospital, during a 10-year period. The results are summarized as follows: 1. Out of 1,434 dermatologic inpatients, 127(8. 9%) patients were diagnosed as drug eruption. 2. The cutaneous manifestations of drug eruptions in the order of frequency were as follows: exanthematous eruption, urticaria, erythema multiforme, Stevens Johnson syndrome, TEN, exfoliative dermatitis, fixed drug eruption and purpura. 3. Antibiotics and antimicrobials were the most common causative agents followed by antipyretics and analgesics, CNS depressant drugs and herb drugs. 4. The 5 most common drugs causing drug eruptions were ampicillin, acetyl salicylic acid, diphenylhydantoin, sulfonamide and phenacetin.
Ampicillin ; Analgesics ; Anti-Bacterial Agents ; Antipyretics ; Dermatitis, Exfoliative ; Dermatology ; Drug Eruptions* ; Erythema Multiforme ; Humans ; Inpatients ; Phenacetin ; Phenytoin ; Purpura ; Salicylic Acid ; Seoul ; Stevens-Johnson Syndrome ; Urticaria

A 36-year-old female patient with sarcoidosis is presented showing lupus pernio, papular skin lesions, cervical lymph node enlargement and lung lesions. Diagnosis was confirmed by characteristic histologic findings of noncaseating granulomas in skin and cervical lymph node, supported by compatible clinical and laboratory features. Methatrexate was administered orally, which resulted in considerable improvement of skin lesions.
Adult ; Diagnosis ; Female ; Granuloma ; Humans ; Lung ; Lymph Nodes ; Methotrexate ; Sarcoidosis ; Skin

No abstract available.
Rectal Prolapse*

Cancer has become a major cause of death in Korea since 1989. Despite the major advances in the treatment of cancer, prevention and early detection is the most effective strategy to decrease the mortality from cancer. The indicence of invasive cervical cancer has declined since the 1950s, and indirect evidence suggests that this decline is the result of the institution of screening with cervical smear. However, cervical cancer continues to be a major health problem in the developing world today, where screening is not universal. Among Korean women, the incidence of cervical cancer is still high and was the 3rd most common cancer following stomach and breast cancer in 2000. If preinvasive conditions would be included, the disease would be the most frequent. The first organized screening programmes were initiated in 1949 at British Columbia, Canada. Since then, cervical cancer screening programmes have been implemented in almost all developed countries. In Korea, opportunistic screening began in the late 1950s, and organized screening began in 1998 by Health Insurance without a consensus meeting. The guidelines for the screening of cervical cancer were developed by National Cancer Center and the Koean Society of Obstetrics and Gynecology in May, 2001 ; and the national screening programmes were developed by the Supporting Evaluation Board of National Cancer Screening Program in December, 2001. This article introduces these programmes.
Breast Neoplasms ; British Columbia ; Canada ; Cause of Death ; Consensus ; Developed Countries ; Early Detection of Cancer ; Female ; Gynecology ; Humans ; Incidence ; Insurance, Health ; Korea ; Mass Screening* ; Mortality ; Obstetrics ; Papanicolaou Test ; Stomach ; Uterine Cervical Neoplasms* ; Vaginal Smears

A clinical study was made on 148 cases of cutaneous malignant tumors that visited the Department of Dermatology at Seoul National University Hospital during a 11-year period from 1973 to 1983. The results were summarized as follows: 1) The incidence of cutaneous malignant tumors in the total number of outpatients visiting the Department of Derrnatology was 0. 025g. 2) There were 90 cases of male (60. 8p,) and 58 cases of female (39. 2g). The ratio of male to female was l. 55: l. Among the 148 cases of cutaneous malignant tumors, the most frequently observed type was basal cell carcinoma, 58 cases (3j.2 p:). The next most frequent types were squamous cell carcinoma, 42 cases(28. 4g) and malignant melanoma, ]1 cases (7. 4g). We described the clinical characteristics of the patients with basal cell carcinoma, squamous cell carcinoma and malignant melanoma that have been observed.
Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Dermatology ; Female ; Humans ; Incidence ; Male ; Melanoma ; Outpatients ; Seoul

A histopathological observation of drug-induced morbilliform eruption and erythema multiforme was made on 32 patients with drug eruption, We found that many histopathologic features of drug-induced morbilliform eruption of basal cell layer with infiltration of derrnoepidermal junction and necrosis of epidermal keratinocyte were similar to those of drug induced erythema multiforme. Therefore, it seems possible to regard the histopathologic features of druginduced morbilliform eruption and erythema multiforrne as a cornmon tissuc reaction with spectral expression.
Drug Eruptions ; Erythema Multiforme* ; Erythema* ; Humans ; Keratinocytes ; Necrosis

No abstract available.
Hemophilia A*

Simple congenital lymphedema is a congenital form of chronic lymphedema of unknown etiology which affects a part or all of the one extremity, especially the lower extremities, at or immediately after birth. A clinical classification of lymphedema was offered by Allen and Ghormley in 1935, based on a study of 300 cases of lymphedema of which 12 cases are simple congenital lymphedema. They classified the cases of lymphedema into two divisions: noninflammatory and inflammatory, with a tabulation of primary and secondary causes. One caes I reporting is classified as being of congenital origin and naturally comes under the noninflammatory group. On May 1960, a 3 year old girl entered to the Department of Orthopaedic Surgery, Kyungpook National University Hospital because of lymphedema of right leg. Since at birth, there were no history of skin infection, cellulitis and lymphangitis etc. Gross appearance of the skin of the affecte leg revealed leather like consistency and thickening. One week of preoperative preparation of the patient was sustained absolute bed rest with elevation of affected limb to ease drainage of lymphatic fluid. The two staged operation of Homans procedure were performed under general anesthesia, first to medical half and second to remaining lateral half of the affected leg. The end result was relatively good in decreasing the circumfence of affected leg but it was not quite acceptable in its cosmetic effect. The literature on primary lymphedema is reviewed.
Anesthesia, General ; Bed Rest ; Cellulitis ; Classification ; Drainage ; Extremities ; Female ; Gyeongsangbuk-do ; Humans ; Leg ; Lower Extremity ; Lymphangitis ; Lymphedema ; Parturition ; Skin