No abstract available.
Eosinophils* ; Humans ; Parotid Gland* ; Radiotherapy*

To examine AZT resistance of HIV-1 isolates from AZT treated or untreated Korean, several biological characteristics such as syncytium formation, HIV-1 reverse transcriptase activity and the p24 antigen production in MT-2 cells infected with 4 HRT_1 isolates were determined. As controls, we tested HIV-1 HTLV-IIIB and pre-drug isolate as AZT susceptible strains, in addition to HIV-1 RTMC/MT-2 and post-drug isolate as AZT resistant strains. When the inoculum size of HIV-1 was 300 TCID50well and 100 TCID50/well, the AZT susceptibility of AZT untreated HIV-1 isolates 8806 and 9571 were similar to that of HIV-1 HTLV-IIIB and AZT-susceptible HIV-1 strains. When we evaluated AZT resistance of isolates HRs-1 8812 and 9113 treated with AZT for 36 months by observation of syncytium formation, HIV-1 8812 showed resistance simillar to that of HIV-1 RTMC/MT-2 strain forming syncytium up to AZT 1microgram/ml, and HIV-1 9113 showed resistance identical with that of AZT-resistant HIV-1 strain which formed syncytium up to AZT 10 microgram/ml. Especially, when we evaluated AZT resistance by HIV-1 reverse transcriptase activty and the p24 antigen production, HIV-1 isolates 8812 and 9113 showed much higher resistance (>10 - 200 fold) compared with HN-1 RTMC/MT-2 and AZT-resistant HIV-1 strain.
Giant Cells ; HIV-1* ; Korea* ; Population Characteristics ; RNA-Directed DNA Polymerase ; Zidovudine*

PURPOSE: The purpose of this study was to review sexual abuse prevention education program for Korean elementary school students.METHODS: Whittemore and Knafl's integrative review methods were used and Gough's weight of evidence was employed as a quality appraisal tool. Articles published in Korean or English were identified through electronic search engines and scholarly web sites using three keywords: “elementary school student”, “sexual abuse”, and “prevention education”. Peer-reviewed articles published between 2000 and 2018 were included in this review.RESULTS: Twelve articles met the inclusion criteria and were appraised as being high-quality. Among the 12 selected studies, seven were descriptive, while five were intervention studies. Sexual abuse prevention education programs were effective in improving perceptions, knowledge, attitudes, and preventive behaviors among elementary school students. However, deficiencies were found in the variety of educational methods, utilization of experts, and standardization of the content of sexual abuse prevention education.CONCLUSION: We need to provide various educational methods that are appropriate for specific developmental stages, and the sexual abuse prevention content should draw upon the current sexual education program administered to this population. Furthermore, parents and trained teachers or school health teachers should be included to provide effective education programs for elementary students.
Child ; Child Abuse, Sexual ; Education ; Humans ; Korea ; Parents ; School Health Services ; Search Engine ; Sex Offenses

PURPOSE: To investigate the relationships among mother's perception of her own newborn, her caring-confidence level, and her child-rearing attitude; and to provide data for developing effective nursing education programs on maternal newborn care. METHOD: Explorative survey questionnaires were completed by 159 married mothers of newborns from November 2003 to March 2004. Data were analyzed using SPSS/Win 10.0 by t-test and Pearson's Correlation coefficient. RESULTS: The mean scores of the mother's perception of her own newborn, her caring-confidence level, and her child-rearing attitude were .26, 3.13, and 3.43 respectively. There was a positive correlation between mother's perception of her own newborn and her child-rearing attitude. There was a significant correlation between mothers caring-confidence level and her child-rearing attitude. Score of caring-confidence was significantly different depending on the availability of helper and history of delivery. CONCLUSION: Availability of helper and history of delivery significantly affected mothers caring-confidence. This in turn, along with mothers perception of her own newborn, enhanced mothers child-rearing attitude. Thus, an effective education for mothers should include these factors.
Education ; Education, Nursing ; Humans ; Infant, Newborn* ; Mothers* ; Child Health ; Surveys and Questionnaires

PURPOSE: The objective of this study was to understand the caring experience of families with terminal cancer patients. METHOD: This was designed to be an inductive and descriptive study. Forty-seven families with terminal cancer patients were interviewed in depth and collected data were examined through content analysis. RESULT: The main categories of difficulties found in this study were "suffering of patient", "emotional suffering of family", "bereavement of patient", "difficulties in coping", "problems in treatment", "incurable situation", "family problems", "relationship with other people", "economic problems", "spiritual problems", "problems in the future", "informing patients of their condition", "preparing death", "emotional unstability", "meaninglessness", "unkindness of medical teams", "poor environment for treatment", "difficulties in hospital environment" and "economic burden". CONCLUSION: The main point found from this result was that families taking care of terminal cancer patients are suffering emotionally from watching the patients' pains and had difficulties in coping with the patients' situation and treatment. In addition, they had negative experiences in medical teams attitude and hospital environment. This result can be used as an important guide for nurses to assess families' needs in the terminal care setting.
Humans ; Terminal Care

No abstract available.
Humans ; Inpatients*

Congenital self-healing reticulohistiocytosis (CSHRH) is a rare Langerhans cell disorder usually showing spontaneous resolution within 3-4 months. By electron microscopy, the identification of Birbeck granules and laminated dense bodies in the infiltrated cells is mandatory for the diagnosis of CSHRH. However, in some reported cases, Birbeck granules could not be demonstrated and only cytoplasmic dense bodies were seen. If the lesion is more advanced, Birbeck granules are transformed to lysosomes, i.e., 'unique phagosomes', in which they are degraded. A 2-month-old Korean girl presented with congenital, numerous red-brown pigmented papules on the left side of trunk and upper extremity without systemic symptoms. A biopsy specimen demonstrated papillary dermis containing epidermotropic infiltrates of histiocytes with abundant eosinophilic cytoplasm. Some had kidney-shaped nuclei and PAS-positive cytoplasmic inclusions. Immunohistochemically, infiltrating cells expressed S-100 protein and ultrastructurally, no Birbeck granules but many dense laminated bodies and unique phagosomes were found. It was ten months since the skin lesions developed that they have started resolving.
Biopsy ; Cytoplasm ; Dermis ; Diagnosis ; Eosinophils ; Female ; Histiocytes ; Humans ; Inclusion Bodies ; Infant ; Lysosomes ; Microscopy, Electron ; Phagosomes ; S100 Proteins ; Skin ; Upper Extremity

We reported two cases of clinically typical melasma presenting with unusual histopathologic findings. In one case, the epidermal melanocytes were markedly increased in number and protruded into the dermis, and in the other case, increased epidermal pigmentation as well as dermal melanocytosis were found. We suggested that the various treatment modalities of melasma should be applied depend on its histopathologic finding.
Melanosis/*pathology ; Melanocytes/pathology ; Humans ; Female ; Epidermis/pathology ; Dermis/pathology ; Adult

PURPOSE: This study is to identify the present situation of children's hospice and to find the developing strategies for child hospice system in Korea. METHOD: The data was collected from both literatures and the recent data provided by the government. The direction of future of children's hospice cared in Korea was predicted based on the literature analysis and the report and policy of government. RESULT: In Korea, the system of the child hospice is not processing. There are the importance differences between children and adult in that the characteristics and approach of the hospice care. All medical personnel and the people related to hospice care including children and their family should be recognized the necessity of the children's hospice care. The following strategies is needed for setting up the child hospice: the principles and standards, recognizing of the necessities, developing of educational program for the specialist and the systemic children's hospice program, and the organization of child hospice. CONCLUSION: Directions suggested from this study have the importance of child hospice to establish and develop well in Korea for both children with life-threatening disease and their families.
Adult ; Child ; Hospice Care* ; Hospices* ; Humans ; Korea* ; Specialization ; Child Health

PURPOSE: The purpose of this study was to identify the relationship between self-esteem and meaning of life in higher grade elementary school students. METHODS: Four hundred eighty four elementary school students in their 4 ~ 6th-grade at S, G and C City were recruited by convenient sampling. Data were collected from August to October, 2008 using a self-reported questionnaire. The collected data were analyzed by the SPSS/WIN 12.0 program with mean, standard deviation, t-test, ANOVA, Duncan's test, and Pearson's correlation. RESULTS: The average score of meaning of life was 3.07 +/- 0.38 and that of self-esteem was 3.43 +/- 0.62. There were significant differences in self-esteem according to variables region and religion, and in meaning of life scores according to variables region, grade, sex and religion. There was a significant positive correlation between self-esteem and meaning of life. CONCLUSION: Self-esteem and meaning of life should be considered as important factors for healthy development in the elementary school period. Self-esteem should be considered as a main content in developing programs for finding meaning of life for higher grade elementary school students.
Humans ; Religion and Sex ; Self Concept ; Surveys and Questionnaires