No abstract available.
Eosinophils* ; Humans ; Parotid Gland* ; Radiotherapy*

To examine AZT resistance of HIV-1 isolates from AZT treated or untreated Korean, several biological characteristics such as syncytium formation, HIV-1 reverse transcriptase activity and the p24 antigen production in MT-2 cells infected with 4 HRT_1 isolates were determined. As controls, we tested HIV-1 HTLV-IIIB and pre-drug isolate as AZT susceptible strains, in addition to HIV-1 RTMC/MT-2 and post-drug isolate as AZT resistant strains. When the inoculum size of HIV-1 was 300 TCID50well and 100 TCID50/well, the AZT susceptibility of AZT untreated HIV-1 isolates 8806 and 9571 were similar to that of HIV-1 HTLV-IIIB and AZT-susceptible HIV-1 strains. When we evaluated AZT resistance of isolates HRs-1 8812 and 9113 treated with AZT for 36 months by observation of syncytium formation, HIV-1 8812 showed resistance simillar to that of HIV-1 RTMC/MT-2 strain forming syncytium up to AZT 1microgram/ml, and HIV-1 9113 showed resistance identical with that of AZT-resistant HIV-1 strain which formed syncytium up to AZT 10 microgram/ml. Especially, when we evaluated AZT resistance by HIV-1 reverse transcriptase activty and the p24 antigen production, HIV-1 isolates 8812 and 9113 showed much higher resistance (>10 - 200 fold) compared with HN-1 RTMC/MT-2 and AZT-resistant HIV-1 strain.
Giant Cells ; HIV-1* ; Korea* ; Population Characteristics ; RNA-Directed DNA Polymerase ; Zidovudine*

PURPOSE: The purpose of this study was to review sexual abuse prevention education program for Korean elementary school students.METHODS: Whittemore and Knafl's integrative review methods were used and Gough's weight of evidence was employed as a quality appraisal tool. Articles published in Korean or English were identified through electronic search engines and scholarly web sites using three keywords: “elementary school student”, “sexual abuse”, and “prevention education”. Peer-reviewed articles published between 2000 and 2018 were included in this review.RESULTS: Twelve articles met the inclusion criteria and were appraised as being high-quality. Among the 12 selected studies, seven were descriptive, while five were intervention studies. Sexual abuse prevention education programs were effective in improving perceptions, knowledge, attitudes, and preventive behaviors among elementary school students. However, deficiencies were found in the variety of educational methods, utilization of experts, and standardization of the content of sexual abuse prevention education.CONCLUSION: We need to provide various educational methods that are appropriate for specific developmental stages, and the sexual abuse prevention content should draw upon the current sexual education program administered to this population. Furthermore, parents and trained teachers or school health teachers should be included to provide effective education programs for elementary students.
Child ; Child Abuse, Sexual ; Education ; Humans ; Korea ; Parents ; School Health Services ; Search Engine ; Sex Offenses

We reported two cases of clinically typical melasma presenting with unusual histopathologic findings. In one case, the epidermal melanocytes were markedly increased in number and protruded into the dermis, and in the other case, increased epidermal pigmentation as well as dermal melanocytosis were found. We suggested that the various treatment modalities of melasma should be applied depend on its histopathologic finding.
Melanosis/*pathology ; Melanocytes/pathology ; Humans ; Female ; Epidermis/pathology ; Dermis/pathology ; Adult

Congenital self-healing reticulohistiocytosis (CSHRH) is a rare Langerhans cell disorder usually showing spontaneous resolution within 3-4 months. By electron microscopy, the identification of Birbeck granules and laminated dense bodies in the infiltrated cells is mandatory for the diagnosis of CSHRH. However, in some reported cases, Birbeck granules could not be demonstrated and only cytoplasmic dense bodies were seen. If the lesion is more advanced, Birbeck granules are transformed to lysosomes, i.e., 'unique phagosomes', in which they are degraded. A 2-month-old Korean girl presented with congenital, numerous red-brown pigmented papules on the left side of trunk and upper extremity without systemic symptoms. A biopsy specimen demonstrated papillary dermis containing epidermotropic infiltrates of histiocytes with abundant eosinophilic cytoplasm. Some had kidney-shaped nuclei and PAS-positive cytoplasmic inclusions. Immunohistochemically, infiltrating cells expressed S-100 protein and ultrastructurally, no Birbeck granules but many dense laminated bodies and unique phagosomes were found. It was ten months since the skin lesions developed that they have started resolving.
Biopsy ; Cytoplasm ; Dermis ; Diagnosis ; Eosinophils ; Female ; Histiocytes ; Humans ; Inclusion Bodies ; Infant ; Lysosomes ; Microscopy, Electron ; Phagosomes ; S100 Proteins ; Skin ; Upper Extremity

The purpose of this study is to explore and describe the lived experience of adolescents with physical handicap by means of the Colaizzi's phenomenological method. The participants were 15 adolescents, 10-19 years old, who were experiencing physical handicap. Significant statements from data were extracted. From these formulated meanings, 27 themes, 10 clusters of theme and 4 categories were constructed. Major theme clusters that were emerged from the analysis are 'denial', 'despair', 'social isolation', 'being despised', 'not being treated as a member of society', 'getting the power in love around people', 'accepting the physical handicap', 'feeling the joy and one's life worth living', 'depending on the religion', and 'the feeling of achievement by the effort and the service'. In order to help the adolescents with physical handicap overcome their difficulty and cope to the social environment, nurses need to understand the essential theme clusters of the experience of adolescents with physical disability.
Adolescent* ; Humans ; Love ; Social Environment ; Child Health

The purpose of this study is to explore and describe the lived experience of adolescents with physical handicap by means of the Colaizzi's phenomenological method. The participants were 15 adolescents, 10-19 years old, who were experiencing physical handicap. Significant statements from data were extracted. From these formulated meanings, 27 themes, 10 clusters of theme and 4 categories were constructed. Major theme clusters that were emerged from the analysis are 'denial', 'despair', 'social isolation', 'being despised', 'not being treated as a member of society', 'getting the power in love around people', 'accepting the physical handicap', 'feeling the joy and one's life worth living', 'depending on the religion', and 'the feeling of achievement by the effort and the service'. In order to help the adolescents with physical handicap overcome their difficulty and cope to the social environment, nurses need to understand the essential theme clusters of the experience of adolescents with physical disability.
Adolescent* ; Humans ; Love ; Social Environment ; Child Health

No abstract available.
Humans ; Inpatients*

PURPOSE: The purpose of this study was to identify the relationship between self-esteem and meaning of life in higher grade elementary school students. METHODS: Four hundred eighty four elementary school students in their 4 ~ 6th-grade at S, G and C City were recruited by convenient sampling. Data were collected from August to October, 2008 using a self-reported questionnaire. The collected data were analyzed by the SPSS/WIN 12.0 program with mean, standard deviation, t-test, ANOVA, Duncan's test, and Pearson's correlation. RESULTS: The average score of meaning of life was 3.07 +/- 0.38 and that of self-esteem was 3.43 +/- 0.62. There were significant differences in self-esteem according to variables region and religion, and in meaning of life scores according to variables region, grade, sex and religion. There was a significant positive correlation between self-esteem and meaning of life. CONCLUSION: Self-esteem and meaning of life should be considered as important factors for healthy development in the elementary school period. Self-esteem should be considered as a main content in developing programs for finding meaning of life for higher grade elementary school students.
Humans ; Religion and Sex ; Self Concept ; Surveys and Questionnaires

Restriction of eye movement after surgery is an unusual but troublesome complication. A patient presented with a limitation of abduction after a 5 mm resection of medial rectus muscle and an 8 mm recession of lateral rectus muscle. Since the forced duction test was positive, restrictive factors were suggested to be implicated. A reparative operation was performed at the postoperative 9 month, and the forced duction test was negative after releasing the resected medial rectus muscle. The patient showed an improved abduction after recessing the resected muscle. Even after an uneventful surgery, resection of an extraocular muscle may cause restriction of ocular rotation caused by muscle scarring to the sclera or by an increased tightness of the muscle.
Adolescent ; Case Report ; Exotropia/*surgery ; *Eye Movements ; Human ; Male ; Ocular Motility Disorders/*etiology/*physiopathology ; Oculomotor Muscles/*physiopathology/*surgery ; Ophthalmologic Surgical Procedures/*adverse effects ; Postoperative Period