The Objectives of this research is to determine the effect of aerobic exercise program on health status and physical fitness in patients after the stem cell transplantation. This research design is one-group pretest-posttest design. Sixteen subjects were selected from one university hospital in Seoul for the study. they was carried out aerobic exercise three to five times a week for 12 weeks. The period of data collection was from February to July, 2000. The collected data was analysed by descriptive analysis, paired t-test, content analysis SAS program was used for the statistical analysis. The results are as follows: 1. There was a significant improvement in the Physical functioning, Vitality and Reported change (t=2.39, p=0.03: t=2.35, p=0.03: t=2.58, p=0.02) but no change was observed in the Role physical. General health perception, Bodily pain, Social functioning, Role emotional and Mental health. 2. There was a significant improvement in the physical fitness (higher V02 max, t=2.43, p=0.02: lower systolic pressure, t=-4.09, p=0.001: lower diastolic pressure, t=-3.43, p=0.002: lower pulse rate, t=-3.43, p = 0.004: higher muscle sustaining power, t=2.79, p=0.015: higher muscle power, t=5.18 p=0.000: higher power of beginning, t=5.55, p=0.001: higher the sense of equilibrium, t=3.57, p=0.003: higher Hemoglobin, t=5.92, p=0.000: higher Hematocrit, t=5.38, p=0.000). Therefore, this study will provide a theoretical background for patients after stem cell transplantation to understand the importance of physical exercise and maintain physical exercise: and for other researches to refer to the results for exercise protocol of rehabilitation program.
Blood Pressure ; Data Collection ; Exercise* ; Heart Rate ; Hematocrit ; Humans ; Mental Health ; Physical Fitness* ; Rehabilitation ; Research Design ; Seoul ; Stem Cell Transplantation* ; Stem Cells*

PURPOSE: The purpose of this research is to identify factors influencing anticipatory nausea and vomiting in cancer patients. METHODS: The conceptual framework was derived from Roy's Adaptation Model. The subjects for this study were 66 adult patients with various types of cancers, who were scheduled for a third cycle of chemotherapy or above. RESULTS: 47% of the patients experienced anticipatory nausea and vomiting. CONCLUSION: The study identified two factors, psychological symptoms (p=.002) and severity of post-chemotherapy nausea and vomiting(p=.004), which are directly related to anticipatory nausea and vomiting. These two factors accounted for 39.5% of the anticipatory nausea and vomiting. Identified environmental cues were awareness of hospital setting, sensory stimuli, and experience of chemotherapy which induced nausea and vomiting. Strategies for relieving anticipatory nausea and vomiting taken by cancer patients were religion, reminiscence, distracting imagery, positive thinking, relaxation and physical exercise.
Adult ; Cues ; Drug Therapy ; Exercise ; Humans ; Nausea* ; Psychology ; Relaxation ; Thinking ; Vomiting*

PURPOSE: The Purpose of this research was to develop the integrative exercise program for the elderly. METHOD: The first step was to survey the elder's health status and general health problems. The second step was to design the exercise type, intensity, time and frequency. RESULT: 1. Elders who implement the integrative exercise program had weaker health status, lower physical performance and more depression than any other places. 2. The integrative exercise program developed the preparation stage composed of stretching and Yudongkong-Ki exercise, the central stage was composed of range of motion exercise, muscle strength exercise and aerobic exercise with favorite and popular Korean music. The finishing stage was composed of joint rounding and Yudongkong-Ki exercise. The exercise intensity was RPE(rating perceived exertion) 10-11, maximal pulse rate 40-60%, duration started from 20min to 50min and frequency is 2-3times/wk. CONCLUSION: The integrative exercise program developed by the researcher is tailored exercise that is more applicable to individual cases in community settings. Eventually, the program is safely applicable to the elders, and is expected to improve the elders' physical function and quality of life.
Aged* ; Depression ; Exercise ; Heart Rate ; Humans ; Joints ; Muscle Strength ; Music ; Quality of Life ; Range of Motion, Articular

No abstract available.
Hepatitis*

PURPOSE: The purpose of this research was to determine the effect of an exercise program on the health status and depression in the elderly. METHOD: The research design was a nonequivalent control group pre-post test design. The exercise program (experimental group) consisted of 22 elderly over a period exercising for 12weeks, 3 days/week. The phone counselling about exercise and health(control group) was applied for 12 weeks for 10-15minutes/day/week. To identify the health status SF-36 was utilized and the GDS was used for depressionanalysis. The data was collected from May 2001 to July 2001. RESULT: The effect of the exercise appeared significant in the subarea of health status (physical function, physical role, mental health, general health) and depression. The effect of the phone counselling was appeared significant in subarea of health status - bodily pain. The effect of the exercise and the phone counselling did not appear significant. CONCLUSION: The exercise designed for the elderly promotes health in the elderly and further evaluation about the effect on exercise and phone counselling is needed.

We observed 285 cases of culture proved shigellosis from Jan. 1978 to July 1981 at W.M.B.H. in Busan. We specially observed the clinical and bacteriological response to Oxolinic acid in 59 cases from Jan. to July 1981. The following results were obtained. 1. The most commonly isolated shigella strains was Sh. flexneri (85.3%) followed by Sh. sonnei (7.4%), Sh. boydii (4.2%) and Sh. dysenteriae(3.2%). 2. Antibiotic sensitivity test revealed that more than 90% of strains were resistant to Tetracycline, Chloramphenicol and Ampicillin. Resistance strains to Gentamycin and Oxocid were found in less than 12.2% and 14.3% respectively. 3. The multiple antibiotic resistant strains were observed in about 80% of 59 strains, which were resistant to 3~5 antibiotics. The most of these strains were resistant to Ampicillin, Chloramphenicol and Tetracycline. In 3 cases it was resistant to all kinds of antibiotics but oxolinic acid. 4. Oxolinic acid showed growth-inhibitory zone of more than 11 mm with the concentration of 2mcg/ml in 95% and M.I.C. value of less than 0.76mcg/ml in 90%. 5. After administration of Oxolinic acid, there was clinical response within 2 days in 76.5% and conversion to negative stool culture within 2days in 68.8%. 6. Compared with placebo group, there was parallel clinical and bacteriologic effectiveness between Oxolinic acid and Rifampin.
Ampicillin ; Anti-Bacterial Agents ; Asthma* ; Busan ; Chloramphenicol ; Dermatitis, Atopic* ; Dysentery, Bacillary ; Gentamicins ; Oxolinic Acid ; Rifampin ; Shigella ; Tetracycline

We observed 285 cases of culture proved shigellosis from Jan. 1978 to July 1981 at W.M.B.H. in Busan. We specially observed the clinical and bacteriological response to Oxolinic acid in 59 cases from Jan. to July 1981. The following results were obtained. 1. The most commonly isolated shigella strains was Sh. flexneri (85.3%) followed by Sh. sonnei (7.4%), Sh. boydii (4.2%) and Sh. dysenteriae(3.2%). 2. Antibiotic sensitivity test revealed that more than 90% of strains were resistant to Tetracycline, Chloramphenicol and Ampicillin. Resistance strains to Gentamycin and Oxocid were found in less than 12.2% and 14.3% respectively. 3. The multiple antibiotic resistant strains were observed in about 80% of 59 strains, which were resistant to 3~5 antibiotics. The most of these strains were resistant to Ampicillin, Chloramphenicol and Tetracycline. In 3 cases it was resistant to all kinds of antibiotics but oxolinic acid. 4. Oxolinic acid showed growth-inhibitory zone of more than 11 mm with the concentration of 2mcg/ml in 95% and M.I.C. value of less than 0.76mcg/ml in 90%. 5. After administration of Oxolinic acid, there was clinical response within 2 days in 76.5% and conversion to negative stool culture within 2days in 68.8%. 6. Compared with placebo group, there was parallel clinical and bacteriologic effectiveness between Oxolinic acid and Rifampin.
Ampicillin ; Anti-Bacterial Agents ; Asthma* ; Busan ; Chloramphenicol ; Dermatitis, Atopic* ; Dysentery, Bacillary ; Gentamicins ; Oxolinic Acid ; Rifampin ; Shigella ; Tetracycline

Hepatoblastoma is a primary embryonic liver tumor usually found in children. It extremely rarely occurs in adults. We report a case of hepatoblastoma in a 56 year old man with chronic hepatitis B of 10years duration. Laboratory investigation of the patient on admission showed a marked elevation of alpha-fetoprotein in serum. Ultrasonography and Computerized tomography scan revealed a primary tumor, 6x7cm in size, in the right lobe. The tumor removed by a right lobectomy. Complete removal of the tumor is the treatment which is potentially curative provided that lesion is confined within the liver capsule. The literature revealed and a case of this tumor reviewed.
Adult* ; alpha-Fetoproteins ; Child ; Hepatitis B, Chronic ; Hepatoblastoma* ; Humans ; Liver ; Middle Aged ; Ultrasonography

Many ocular findings have been shown in patients with chronic renal failure. There has been no systematic study on ocular manifestations in patients with chronic renal failure. The medical records of 349 patients with chronic renal failure, who were referred to ohthalmologic department, were reviewed. Of 349 patients, 109 were renal transplanted patients, 118 were hemodialysis, and 122 were CAPD. Sixty-five % were male, 35% were female, and their mean age was 42 years old. For renal transplanted patients, 47% had a visual acuity of 1.0 or better, while 6% had worse than finger counting. Nineteen % and 15% of hemodialysis, and 19% and 24% of CAPD patients had a visual acuity of 1.0 or better and worse than finger counting, respectively. Hypertension was the most common associated systemic disease. Primary causes of renal failure were chronic glomerulonephritis(44.4%), diabetic nephropathy(17.2%), hypertensive nephropathy(4.6%), and CRF NOS(29.5%). Hypertensive retinopathy(45.6%) was the most common ocular manifestation of all patients with renal failure. Others were cataract, diabetic retinopathy, ischemic optic neuropathy and retinal detachment. These results suggest that ocular complications are common in patients with chronic renal failure and therefore, close follow up has to be performed after renal transplantation and during dialysis.
Adult ; Cataract ; Diabetic Retinopathy ; Dialysis ; Female ; Fingers ; Follow-Up Studies ; Humans ; Hypertension ; Hypertensive Retinopathy ; Kidney Failure, Chronic* ; Kidney Transplantation ; Male ; Medical Records ; Optic Neuropathy, Ischemic ; Peritoneal Dialysis, Continuous Ambulatory ; Renal Dialysis ; Renal Insufficiency ; Retinal Detachment ; Visual Acuity

PURPOSE: The evolution of cirrhosis from chronic inflammatory liver disease represents a dysmorphogenic "response to injury". It is important to understand how inflammatory cytokines, known to be associated with such responses, influence the growth of different cell populations within the liver. The purpose of this work is to establish a role of serum interleukin-6 (IL-6) in liver regeneration following partial hepatectomy in N-nitrosodieth ylamine (DEN)-induced cirrhotic rats. METHODS: Male Sprague-Dawley rats were used for this study. Liver cirrhosis was induced using DEN (100 mg/kg) given once a week for 6 weeks. In Group I (n=18), 70% partial hepatectomy was accomplished and then the resected liver weight, regenerated liver weight, serum IL-6, and serum GOT/GPT was determined on postoperative days 1, 2, and 4 and at intervals. In Group II (n=19), partial hepatectomy was carried out and Laennec, a hepatocyte growth promoter, was injected on preoperative 1 day and postoperative days 1 and 2. RESULTS: The value of serum GOT in Group I was 415 IU/ml on the first postoperative day and peaked at 1870 IU/ml on the third day. In Group II, the level of serum GOT was 404 IU/ml on the first postoperative day and peaked at 593 IU/ml on the third day, then decreased gradually thereafter. The value of serum IL-6 was 106.54 pg/ml on the first postoperative day, 130.59 pg/ml on the 14th postoperative day in Group I, however in Group II, it was 40 pg/ml on thefirst postoperative day and then decreased to 29.18 pg/ml on the 14th postoperative day. The percentages of regenerated weights of liver at intervals following the 70% partial hepatectomy was 55.1% on the first postoperative day, and 102.3% on the 4th week in Group I and 60.4% on the first postoperative day, 95.8% on the first week postoperatively, and 116.1% on the 2nd week in Group II. CONCLUSION: As the value of serum IL-6 was sustained below 40 pg/ml, which was the value on the first postopeative day following partial hepatectomy with Laennec treatment, the resected liver was rapidly regenerated and restored to normal liver function. In cirrhotic liver, regenerative activity was related to serum IL-6 level, so downregulation of serum IL-6 might be helpful to the regeneration of resected liver.
Animals ; Cytokines ; Down-Regulation ; Fibrosis ; Hepatectomy* ; Hepatocytes ; Humans ; Interleukin-6* ; Liver Cirrhosis ; Liver Diseases ; Liver Regeneration* ; Liver* ; Male ; Rats* ; Rats, Sprague-Dawley ; Regeneration ; Weights and Measures