1.Simultaneous Determination of Estazolam and Diazepam in Serum With HPLC
Li ZHANG ; Lin HE ; Shiming SUN ; Jing TAN
China Pharmacy 1991;0(02):-
OBJECTIVE:To establish HPLC method for simultaneous determination of estazolam and diazepam in serum METHODS:The mobile phase consisted of methanol-water-triethylamine-acetic acid(55∶45∶0 5∶0 35)and the ?max was 254nm Phenytoin was adopted as the internal standard The drugs were extracted by diethyl ether under the alkaline condition RESULTS:The calibrating curves of estazolam and diazepam were linear in the ranges of 0 52~38 62?g/ml and 0 50~40 16?g/ml respectively CONCLUSION:The method was appropriate for determination of estazolam and diazepam qualitatively and quantitatively in intoxication accident
2.Chemical constituents from Cucubalus baccifer
Yongxian CHENG ; Jun ZHOU ; Shiming DENG ; Ninghua TAN ;
Chinese Traditional and Herbal Drugs 1994;0(05):-
Object To study the chemical constituents of our folk herb, Cucubalus baccifer L Methods The components were separated on Diaion HP 20 and silica gel column chromatography and the structures were identified by spectral evidence Results Six compounds from ethyl acetate extracts were elucidated as 6? methoxy piperidin 2 one (Ⅰ), pterolactam (Ⅱ), 5, 7, 4′ trihydroxyflavone (Ⅲ), 4 hydroxy 3 methoxybenzopropanyl acid (Ⅳ), 4 hydroxybenzoaldehyde (Ⅴ), and 4 hydroxybenzoic acid (Ⅵ) Conclusion Compound Ⅰ was a new naturally occurring compound and others were first isolated from this plant
3.Progress of TSC-22 gene research.
Journal of Central South University(Medical Sciences) 2011;36(7):592-596
Transformation growth factor β -inducible gene 22 (TSC-22) is a putative negative growth regulation and tumor suppressor gene. It has the ability to combine with other transcription factors to regulate the cell growth and apoptosis. TSC-22 is lowly expressed in many types of tumors,which may be related to the tumorgenesis and development.
Animals
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Genes, Tumor Suppressor
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Humans
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Leucine Zippers
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genetics
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Neoplasms
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physiopathology
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Repressor Proteins
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genetics
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physiology
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Transcription Factors
4.Discussion of teaching reform in medical imaging based on the optimized integration of imaging diagnostics course
Lilian TAN ; Shiming LIU ; Zhiming LI ; Mingsong XU ; Deji CHEN ; Jindai JIANG
Chinese Journal of Medical Education Research 2012;11(2):184-186
According the development requirement of medical imaging skill,centered on diseases,we discussed the teaching reform of imaging diagnostics course,including the optimized integration of the course,bilingual teaching,teaching methods,format of subject test and strengthening practice teaching,hoping to improve the whole team' professional quality.